A5064809548- Menopause: Health Impacts and Treatments
- Phytoestrogen effects and research
- Nutritional Studies and Diet
- Diet and metabolism studies
- Antioxidant Activity and Oxidative Stress
- Maternal Mental Health During Pregnancy and Postpartum
- Obesity, Physical Activity, Diet
- Estrogen and related hormone effects
- Tryptophan and brain disorders
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Menstrual Health and Disorders
- Breastfeeding Practices and Influences
- Stress Responses and Cortisol
- Pregnancy-related medical research
- Eating Disorders and Behaviors
- Maternal and Perinatal Health Interventions
- Hair Growth and Disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Hearing, Cochlea, Tinnitus, Genetics
- Neonatal skin health care
- Coffee research and impacts
- Cardiovascular Issues in Pregnancy
- Nutrition, Health and Food Behavior
- Fatty Acid Research and Health
Institute of Science Tokyo
2024
Tokyo Medical and Dental University
2014-2023
The University of Tokyo
2022
This study aimed to investigate the effects of grape seed proanthocyanidin extract (GSPE) on blood pressure and vascular endothelial function in middle-aged Japanese adults with prehypertension. We conducted a randomized, double-blind, placebo-controlled 6 men 24 women aged 40–64 years old. The participants were randomized receive tablets containing either low-dose (200 mg/day) or high-dose (400 GSPE, placebo, for 12 weeks. Systolic diastolic pressures (SBP DBP, respectively), brachial...
Many studies have demonstrated the effectiveness of isoflavones on menopausal symptoms; however, these mostly used high dosages. Because high-dose isoflavone may result in endometrial hyperplasia, we investigated whether low-dose aglycone alleviates symptoms similarly to dosages.We conducted a randomized, double-blind, placebo-controlled study 90 healthy women aged 40-60 years who had at least one symptom Menopausal Symptom Scale (MSS). The participants were randomized receive active tablets...
Oxidative stress is known to be a factor in various diseases. In this study, we investigated whether physical and psychological symptoms of menopause, cardiovascular parameters, body composition, lifestyle factors are associated with oxidative middle-aged women. This cross-sectional study used baseline data collected previous that examined the effects dietary supplement on variety health parameters 95 women aged 40 60 years. Participants had been assessed for age, menopausal status, factors....
This study was undertaken to evaluate the prevalence and predictors of storage lower urinary tract symptoms (LUTS) in perimenopausal postmenopausal women attending a menopause clinic.The records 351 aged 40 76 years who enrolled health nutrition education program at clinic were analyzed cross-sectionally. The frequency, nocturia, urge incontinence, stress incontinence estimated based on women's responses Menopausal Health-Related Quality Life Questionnaire. Effects background...
This study aimed to investigate the links between coffee (CF)/green tea (GT) consumption and body composition/cardiovascular parameters in middle-aged Japanese women. We conducted a cross-sectional of 232 women aged 40–65 years who had been referred menopause clinic Tokyo Medical Dental University Hospital November 2007 August 2017. Body composition, cardiovascular parameters, CF/GT frequency were evaluated on their initial visits, using composition analyzer, vascular screening system,...
Preventing adverse pregnancy outcomes is crucial for maternal and child health. Periodontal disease a risk factor many systemic diseases including outcomes, such as preterm birth low weight. In addition, the administration of periodontopathic bacterium
Lecithin is a complex mixture of phospholipids which compose lipid bilayer cell membranes. Lipid replacement therapy, or administration for the purpose repairing dmaged membranes, had been shown to alleviate fatigue. The present study aimed investigate effect soy lecithin on fatigue in middle-aged women, as well other menopausal symptoms and various health parameters.This randomized, double-blind, placebo-controlled included 96 women aged 40 60 years who complained participants were...
Objectives: Many middle-aged women are affected by sleep disturbance. We investigated how subjective insomnia is associated with objective parameters and other background characteristics.Methods: This cross-sectional study used baseline data obtained from 95 aged 40–59 years who participated in another assessing the effects of a dietary supplement. Participants wore an actigraph unit for 3 days to collect information concerning physical activities were then evaluated body composition,...
Women in the menopausal transition and postmenopausal period are affected with vasomotor symptoms, urogenital atrophy, sexual dysfunction, somatic cognitive difficulty, sleep disturbance, psychological problems. It is important to gain a better understanding of complexity diversity climacteric disturbance order optimize treatments for individual patients. The aim this study was identify subgroups Japanese perimenopausal women attending menopause clinic based on their physical symptom...
Background: Although muscle and joint pains are among the most common symptoms in menopausal transition, their underlying mechanisms not precisely known. This study aimed to investigate factors associated with myalgia arthralgia middle-aged women.Methods: We analyzed a cross-sectional manner first-visit records of 305 Japanese women aged 40–59 years who enrolled health nutrition education program at menopause clinic. The prevalence was estimated according participants' responses Menopausal...
Tomato-based food products have health-promoting and disease-preventing effects. Some tomato juice ingredients may health benefits for middle-aged women, including women with menopausal symptoms cardiovascular diseases. We investigated the net effect of intake on several parameters in this age group.An open-label, single-arm study was conducted, involving 95 (40-60-years-old) who had at least one symptom. The participants refrained from foods drinks rich tomato-based 2 weeks prior to during...
This study aimed to investigate the relationship between consumption of various nutrients and bone mineral density (BMD) in middle-aged women. cross-sectional survey was conducted based on clinical records 157 women aged 38–76. Their lumbar spine BMD measured with dual-energy X-ray absorptiometry dietary habits were assessed brief-type self-administered diet history questionnaire. Participants divided into premenopausal (n = 46) postmenopausal 111) groups correlation Z-score (Z-score)...
This study aimed to investigate the prevalence of, and risk factors associated with, feeling of unattractiveness in peri- postmenopausal women.The records 351 women aged 40-76 who enrolled a health nutrition education program at menopause clinic were analyzed cross-sectional manner. Perceptions estimated according responses for item 'feeling less attractive than before' on Menopausal Health-Related Quality Life Questionnaire. Age, menopausal status, body composition, cardiovascular...
The prevalence of cardiovascular diseases increases with age, especially in postmenopausal women. In this study, we investigated the dietary patterns associated body mass and fat Japanese middle-aged women.Cross-sectional.This study used baseline data collected a previous 88 women aged 40-60 years. Participants were assessed for menopausal status, lifestyle factors, composition, habits using brief-type self-administered diet history questionnaire, which provides information on amounts nearly...
This study investigated the nutritional factors that are associated with anxiety and depressive symptoms in Japanese middle-aged elderly women. We conducted a cross-sectional 289 participants aged ≥40 years (mean age = 52.0 ± 6.9 years). Their dietary habits, menopausal status symptoms, varied background factors, such as body composition, lifestyle cardiovascular parameters, were assessed. evaluated using Hospital Anxiety Depression Scale (HADS), where scores of 0–7 points, 8–10 11–21 points...
Abstract Aim This study examined the relationship between postpartum hair loss and psychological symptoms. Methods questionnaire‐based, cross‐sectional included women who had delivered at two facilities completed questionnaire 10–18 months after delivery. Study protocols were sent by mail in parts. Baseline characteristics information regarding pregnancy, delivery, childcare, obtained via a questionnaire. Psychological symptoms assessed Whooley Questions, Generalized Anxiety Disorder 2‐item,...
Although dizziness is one of the most common symptoms menopause, underlying mechanism not precisely known. Therefore, this study aimed to investigate prevalence of, and factors associated with, in peri- postmenopausal women.We conducted a cross-sectional which we analyzed first-visit records 471 Japanese women aged 40 65 years who enrolled health nutrition education program at menopause clinic. The was estimated according participants' responses Menopausal Health-Related Quality Life...
Milk is known to contain various nutrients that may have health benefits for postmenopausal women who are at an increased risk of cardiovascular and musculoskeletal diseases. We investigated the association between normal/high- low-fat milk consumption body composition in Japanese aged 40 60 years. This cross-sectional study used baseline data collected a previous examined effects dietary supplement on variety parameters 85 Participants had been assessed age, menopausal status, lifestyle...
Objectives: This study investigated the links between severity of vasomotor symptoms (VMS) and dietary consumption a variety nutrients.Method: A cross-sectional analysis first-visit records 262 women aged 40–65 years was conducted. The their hot flushes (HF) night sweats (NS) nutrients were evaluated using Menopausal Health-Related Quality Life Questionnaire brief-type self-administered Diet History Questionnaire, respectively. relationships HF/NS intake analyzed separately for 43 major...
Limited data have been reported on the use of proprotein convertase subtilisin/kexin type 9 (PCSK 9) inhibitors during pregnancy in women with familial hypercholesterolemia (FH). Here, we present first case initiating evolocumab (PCSK9 inhibitor) a compound heterozygous FH mother. The patient was 34-year-old primipara severe dyslipidemia and history coronary artery bypass surgery. An elevated low-density lipoprotein cholesterol (LDL-C) level 420 mg/dL detected trimester persistently...
The aim of this study was to investigate the effects unsalted tomato juice intake on cardiovascular risk markers in local Japanese residents. Four hundred and eighty-one residents Kuriyama, Japan, were enrolled study. Throughout year study, they provided with as much wanted. Participants screened for markers, such blood pressure (BP), serum lipid profile, glucose tolerance, before after period. Of participants, 260 participated a detailed their lifestyle factors. average ages 184 male 297...
Abstract This study investigated the relationship between subjective forgetfulness and dietary intake of various nutrients in middle‐aged senior women. A cross‐sectional first‐visit records 245 Japanese women aged 40 or over was performed. The severity classified according to Menopausal Health‐Related Quality Life Questionnaire: none mild (“unforgetful”) moderate severe (“forgetful”). Dietary consumption estimated using brief‐type self‐administered diet history questionnaire. associations 43...
Objective: This cross-sectional study investigated chilliness, which is the most prevalent sexual-vasomotor symptom in middle-aged Japanese women.Methods: First-visit records of 475 women (age 40–65 years) enrolled health and nutrition education program at a menopause clinic were analyzed. Chilliness was estimated based on responses to Menopausal Symptom Scale. Effects age, menopausal status, body composition, cardiovascular parameters, resting energy expenditure, physical fitness, symptoms,...
Objective: This study aimed to investigate whether depressive symptoms at postpartum are associated with oxidative stress and antioxidant activity, as well the during pregnancy.Methods: longitudinal enrolled 84 women in their second trimester of pregnancy. Their were assessed using Edinburgh postnatal depression scale (EPDS), activity reactive oxygen metabolites/8-hydroxy-2′-deoxyguanosine biological potential (BAP) around 26 36 weeks (time points 1 2) gestation, 3–6 days month 3 4)...
Although postpartum hair loss is believed to be common, there little reliable information.