A5036801316- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Hemophilia Treatment and Research
- Hemoglobin structure and function
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- Endoplasmic Reticulum Stress and Disease
- Blood Coagulation and Thrombosis Mechanisms
- Heme Oxygenase-1 and Carbon Monoxide
- Blood groups and transfusion
- Neonatal Health and Biochemistry
- Prenatal Screening and Diagnostics
- Chronic Myeloid Leukemia Treatments
- Erythropoietin and Anemia Treatment
- Chronic Lymphocytic Leukemia Research
- Adenosine and Purinergic Signaling
- Blood donation and transfusion practices
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Toxin Mechanisms and Immunotoxins
- Venous Thromboembolism Diagnosis and Management
- HIV/AIDS drug development and treatment
- Child Nutrition and Water Access
- Cancer-related gene regulation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Lymphoma Diagnosis and Treatment
University of California, San Diego
2018-2025
UC San Diego Health System
2023-2024
University of California San Diego Medical Center
2022
Beth Israel Deaconess Medical Center
2014-2018
Tufts Medical Center
2016-2018
Harvard University
2015
University of Connecticut
2013
Christian Medical College & Hospital
2007-2011
UConn Health
2011
Diarrhoea and water-borne diseases are leading causes of mortality in developing countries. To understand the socio-cultural factors impacting on water safety, we documented knowledge, attitudes practices handling usage, sanitation defecation rural Tamilnadu, India, using questionnaires focus group discussions, a village divided into an upper caste Main lower Harijan colony. Our survey showed that all households stored drinking wide-mouthed containers. The quantity supplied was less colony,...
Summary Objective To investigate the effects of nutritional supplementation on outcome and status south Indian patients with tuberculosis (TB) without human immunodeficiency virus (HIV) coinfection anti‐tuberculous therapy. Method Randomized controlled trial effect a locally prepared cereal–lentil mixture providing 930 kcal multivitamin micronutrient supplement during therapy in 81 newly diagnosed TB alone 22 TB–HIV‐coinfected patients, among whom 51 received 52 did not receive supplement....
Abstract Hemoglobin H (HbH) disease is associated with anemia, ineffective erythropoiesis, and iron overload. We report a case of patient HbH/Hb Constant Spring disease, who was maintained on chronic transfusions as an adult due to symptomatic anemia. Over time, he developed overload started chelation therapy but did not have adequate response chelation. then added erythrocytapheresis were able successfully decrease his burden while managing Therapeutic may be effective treatment strategy...
Crizanlizumab was approved by the United States Food and Drug Administration agency in 2019 for decreasing vaso-occlusive events (VOEs) sickle cell disease (SCD). Data regarding use of crizanlizumab real-world setting are limited. Our goal to identify patterns prescriptions our SCD program evaluate benefits barriers its clinic.We conducted a retrospective analysis patients who received at institution between July 2020 January 2022. We compared acute care usage before after initiation...
Anti-IH is a common cold agglutinin that typically clinically insignificant. We present case resulted in hemolysis. A 32-year-old male patient with transfusion-independent beta-thalassemia intermedia presented symptomatic anemia. His blood sample typed as group B, D+ and demonstrated multiple alloantibodies autoantibodies. He was transfused uneventfully, but re-presented 10 days later recurrent, worsening At this time, transfusion of O, phenotype-matched red cells (RBCs) an acute hemolytic...
Haemophilia patients experience painful joint episodes which may or not be associated with haemarthrosis. We sought to validate a questionnaire developed by the Canadian Society using point-of-care musculoskeletal ultrasound (POC MSKUS) confirm haemarthrosis.The comprised of 20 questions (10 each haemarthrosis and arthritis pain) was administered adult haemophilia reporting Treatment Centre (University California San Diego). confirmed presence (or absence) POC MSKUS [Joint Activity Damage...
<sec> <title>BACKGROUND</title> Chronic kidney disease (CKD) is a significant complication in patients with sickle cell (SCD), leading to increased mortality. </sec> <title>OBJECTIVE</title> This study aims investigate the burden of CKD Medicaid-enrolled adults SCD California, examine differences between male and female individuals, assess mortality rates access specialized care. <title>METHODS</title> retrospective cohort used California Sickle Cell Data Collection program identify monitor...
Background Chronic kidney disease (CKD) is a significant complication in patients with sickle cell (SCD), leading to increased mortality. Objective This study aims investigate the burden of CKD Medicaid-enrolled adults SCD California, examine differences between male and female individuals, assess mortality rates access specialized care. Methods retrospective cohort used California Sickle Cell Data Collection program identify monitor individuals SCD. Medicaid claims, vital records, emergency...