A5049460519- Tissue Engineering and Regenerative Medicine
- Connective tissue disorders research
- Atherosclerosis and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
- Congenital heart defects research
- Connective Tissue Growth Factor Research
- Macrophage Migration Inhibitory Factor
- Pluripotent Stem Cells Research
- Pulmonary Hypertension Research and Treatments
- Lipoproteins and Cardiovascular Health
- Celiac Disease Research and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Reproductive Biology and Fertility
- Cardiac Fibrosis and Remodeling
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Parathyroid Disorders and Treatments
- Apelin-related biomedical research
- Immune Response and Inflammation
- Vascular Anomalies and Treatments
- Protease and Inhibitor Mechanisms
- Helicobacter pylori-related gastroenterology studies
- Angiogenesis and VEGF in Cancer
- IL-33, ST2, and ILC Pathways
- Wnt/β-catenin signaling in development and cancer
- Pancreatitis Pathology and Treatment
Peking University
2025
Peking University Third Hospital
2025
Wuhan University
2022-2024
Zhongshan Hospital of Xiamen University
2024
Renmin Hospital of Wuhan University
2022-2024
Oocyte maturation is crucial for female fertility and embryonic development, encompassing nuclear cytoplasmic maturation. Supportive cells of follicles, such as granulosa cells, are essential oocyte growth Oocytes can achieve without during in vitro (IVM). However, there still a higher chance incomplete these oocytes with mature nuclei compared cultured cells. have lower fertilization rates developmental potential than ones, although underlying mechanisms poorly understood. Identifying key...
Abstract Targeting cardiac remodeling is regarded as a key therapeutic strategy for heart failure. Kielin/chordin‐like protein (KCP) secretory with 18 cysteine‐rich domains and associated kidney liver fibrosis. However, the relationship between KCP remains unclear. Here, we aimed to investigate role of in induced by pressure overload explore its potential mechanisms. Left ventricular (LV) expression was measured real‐time quantitative PCR , western blotting, immunofluorescence staining...
Cardiovascular diseases have been identified as vital factors in global morbidity and mortality recent years. The available evidence suggests that various cytokines pathological proteins participate these complicated changeable diseases. thrombospondin (TSP) family is a series of conserved, multidomain calcium-binding glycoproteins cause cell-matrix cell-cell effects via interactions with other extracellular matrix components cell surface receptors. TSP has five members can be divided into...
Cardiac dysfunction is one of the most common complications sepsis and associated with adverse outcomes high mortality patients. IL-12p40, subunit IL-12 IL-23, has been shown to be involved in a variety inflammation-related diseases, such as psoriasis inflammatory bowel disease. However, role IL-12p40 lipopolysaccharide (LPS)-induced cardiac remains obscure. This study aimed explore LPS-induced its potential mechanisms.In this study, mice were treated LPS expression was determined. Then,...
Patients with ulcerative colitis (UC) are at an increased risk of developing IgG4 related diseases (IgG4-RD). However, the molecular mechanisms not known. This study aimed to investigate potential and drugs treat both UC IgG4-RD. GSE42911 GSE40568 datasets were intersected generate common differentially expressed genes (DEGs). The DEGs then subjected Gene Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) analysis. After a protein-protein interaction network (PPI) analysis, hub...