A5028766186- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Advanced Breast Cancer Therapies
- Cancer Treatment and Pharmacology
- Diabetes Management and Research
- Intravenous Infusion Technology and Safety
- Radiopharmaceutical Chemistry and Applications
- Mobile Health and mHealth Applications
- Medical Imaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Cancer Cells and Metastasis
- Lung Cancer Diagnosis and Treatment
- Diabetes and associated disorders
- Head and Neck Cancer Studies
- Pancreatic function and diabetes
Endocrinology Research Center
2024
Ministry of Health of the Russian Federation
2020
Institute of Oncology NN Petrov
2018
BACKGROUND: Previously, we presented the process of developing a clinical decision support system (CDSS) for adjusting insulin pump (IP) settings in children with type 1 diabetes mellitus (T1D) and assessing agreement recommendations it generates expert opinion. The CDSS demonstrated satisfactory forecasting glucose profile rates between experts. AIM: To evaluate effectiveness safety using T1D, testing hypothesis non-inferiority (with limit -5%) relative increase time range (TIR) over 6...
BACKGROUND: Widely available diabetes devices (continuous glucose monitoring, insulin pump etc.) generate large amount of data and development an advanced clinical decision support system (CDSS), able to automatically evaluate optimize therapy, is relevant. AIM: Development a mathematical model CDSS based on it therapy in children with type 1 (T1D) assessment the agreement between recommendations physician (IP) parameters: basal profile (BP), carbohydrate ratio (CR), correction factor (СF)....
Biopsy of signal (sentinel) lymph nodes (LN) has been performed at the N.N. Petrov National Medical Research Oncology Center, Ministry Health Russia, for almost 20 years. In first few years, contrast-visual method (1 % blue isosulfan and triphenyl methane control) was used in 640 patients with early (T1–2N0M0) breast cancer. 150 from this cohort, standard axillary dissection irrespectively results biopsy. The rate false positive responses varied between 4.6 6.6 %. Since 2012, radioisotope...
Background. Breast cancer is a heterogeneous disease with variety of phenotypic forms. Triple-negative breast (TNBC) one the most aggressive subtypes characterized by high sensitivity to chemotherapy and early recurrence. Due lack efficiency standard therapeutic approaches, it appears extremely important search for new regimens neoadjuvant polychemotherapy (NAPCT). Objective: assess different NAPCT treatment stages T1N1–3 T2–4N0–3 locally advanced TNBC compare eribulin paclitaxel in TNBC....
Abstract An open-label single institution study of sentinel lymph node biopsy prior to neoadjuvant chemotherapy is conducted in the N.N. Petrov research institute oncology. So far 30 patients with locally advanced breast carcinoma (T2-4N0) were included. Mammography, US and SPECT are performed hospitalization so as core subsequent IHC staining determine levels ER, PR, KI67 HER2. Sentinel use radiocompound first cycle chemotherapy. Patients receive 4 6 cycles response evaluation after 2,...
Objective: to evaluate the diagnostic accuracy of sentinel lymph node biopsy after neoadjuvant chemotherapy. Materials and methods: study included 264 patients with early (operable) locally advanced breast cancer (cT1N1-3, cT2N0-3, cT3N0-3, cT4N0-3). All patient underwent corebiopsy histological examination ICH (to determine tumor grade (G), expression ER, PR, Ki67, Her2), fine needle aspiration suspicious axillary nodes. Before, during therapy, all undergo: physical (palpation),...