Yichen Hu

ORCID: 0000-0003-2742-1991
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About
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Research Areas
  • Polysaccharides and Plant Cell Walls
  • Microbial Metabolites in Food Biotechnology
  • Polysaccharides Composition and Applications
  • Food composition and properties
  • Seed and Plant Biochemistry
  • Mycotoxins in Agriculture and Food
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Gut microbiota and health
  • Seaweed-derived Bioactive Compounds
  • Nanoparticle-Based Drug Delivery
  • Traditional Chinese Medicine Analysis
  • RNA Interference and Gene Delivery
  • Proteins in Food Systems
  • Fungal Biology and Applications
  • Cancer therapeutics and mechanisms
  • Postharvest Quality and Shelf Life Management
  • Diet and metabolism studies
  • Curcumin's Biomedical Applications
  • Tea Polyphenols and Effects
  • DNA and Nucleic Acid Chemistry
  • Computational Drug Discovery Methods
  • Protein Hydrolysis and Bioactive Peptides
  • Fermentation and Sensory Analysis
  • Analytical Chemistry and Chromatography

Ministry of Agriculture and Rural Affairs
2019-2025

Chengdu University
2016-2025

Nanchang University
2024-2025

University of Chinese Academy of Sciences
2025

Beijing National Laboratory for Molecular Sciences
2025

Chinese Academy of Sciences
2025

Second Affiliated Hospital of Nanchang University
2024-2025

First Affiliated Hospital of Jiangxi Medical College
2025

Jinhua Central Hospital
2024

Wenzhou Medical University
2024

This study aimed to analyze the therapeutic effect of Rhein on ulcerative colitis (UC) in mice and its possible mechanism. LPS-induced UC cell model DSS-induced mouse were used antiinflammatory vitro vivo, respectively. Network pharmacology analysis was conducted identify potential signaling pathways involved treating UC, results further confirmed through western blotting assay. 16sRNA sequencing performed regulatory gut microbiota mice. As indicated by results, could significantly inhibit...

10.1002/ptr.7429 article EN Phytotherapy Research 2022-03-01

Lotus leaves are often discarded as byproducts in the lotus industry. Polysaccharides regarded one of essentially bioactive components leaves. Therefore, order to promote application functional food industry, deep eutectic solvent (DES) assisted extraction polysaccharides from (LLPs) was optimized, and structural biological properties LLPs extracted by DES hot water were further investigated. At optimal conditions (water content 61.0% DES, temperature 92 °C, liquid-solid ratio 31.0 mL/g time...

10.3390/foods10102330 article EN cc-by Foods 2021-09-30

The leaf of sweet tea (Lithocarpus litseifolius) is widely used as an edible and medicinal plant in China, which rich bioactive polysaccharides. In order to explore promote the application polysaccharides functional food industry, microwave-assisted deep eutectic solvent extraction (MDAE) from leaves was optimized, structural properties biological functions prepared by MDAE (P-DM) were investigated compared with that hot water (P-W). maximum yield (4.16% ± 0.09%, w/w) P-DM obtained under...

10.3390/antiox11081578 article EN cc-by Antioxidants 2022-08-15

Buckwheat sprout is widely consumed as a potential functional and healthy vegetable. Although buckwheat abundant in soluble dietary fibers (SDFs), the information about their structural properties biological functions remains unclear, which largely limits applications foods. Therefore, to promote rational usage of SDFs from sprouts food industry, physicochemical were investigated. Results revealed that rich (41.2–43.3, mg/g). isolated both common Tartary possessed similar chemical...

10.1016/j.lwt.2023.114944 article EN cc-by-nc-nd LWT 2023-06-01

The low targeted drug delivery efficiency, including poor tumor accumulation and penetration uncontrolled release, leads to the failure of cancer therapy. Herein, a multifunctional supramolecular nanoplatform loading triptolide (TPL/PBAETK@GA NPs) was fabricated via host–guest interaction between glycyrrhetinic-acid-modified poly(ethylene glycol)-adamantanecarboxylic acid moiety reactive oxygen species (ROS)/pH cascade-responsive copolymer poly(β-amino esters)-thioketal (TK)-β-cyclodextrin....

10.1021/acsami.3c16022 article EN ACS Applied Materials & Interfaces 2024-02-05

Periplaneta americana, a magic medicinal insect being present for over 300 million years, exhibits desirable therapeutic outcome gastrointestinal ulcer treatment. Nowadays, P. americana ethanol extract (PAE) has been shown to ameliorate ulcerative colitis (UC) by either single-use or in combination with other agents clinics. However, its underlying mechanisms are still seldom known. Herein, we investigated the anti-UC activity of PAE alleviating intestinal inflammation and regulating...

10.3389/fphar.2018.00944 article EN cc-by Frontiers in Pharmacology 2018-08-22
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