A5023020652- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Radiopharmaceutical Chemistry and Applications
- Renal and related cancers
- Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Global Cancer Incidence and Screening
- Frailty in Older Adults
- Multiple and Secondary Primary Cancers
- Medical Imaging Techniques and Applications
- Statistical Methods in Clinical Trials
- Renal and Vascular Pathologies
- Radiation Dose and Imaging
- Economic and Financial Impacts of Cancer
- Sarcoma Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Esophageal Cancer Research and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Occupational and environmental lung diseases
- Soft tissue tumor case studies
Martini-Klinik
2020-2023
Universität Hamburg
2020-2023
University Medical Center Hamburg-Eppendorf
2020-2023
University of Lucerne
2023
Université de Montréal
2020-2022
Luzerner Kantonsspital
2021
Intermediate risk prostate cancer (IR PCa) may exhibit a wide array of phenotypes, from favorable to unfavorable. NCCN criteria help distinguishing between versus unfavorable subgroups. We studied and attempted improve this classification.Within the SEER database 2010-2016, we identified 19,193 IR PCa patients treated with radical prostatectomy. A multivariable logistic regression model predicting was developed externally validated, in addition head-to-head comparison stratification.Model...
Abstract Background To investigate the effect of frailty on short‐term postoperative outcomes and total hospital charges (THCs) in patients with non‐metastatic upper urinary tract carcinoma, treated radical nephroureterectomy (RNU). Methods Within National Inpatient Sample (NIS) database we identified 11 258 RNU (2000‐2015). We used Johns Hopkins frailty‐indicator to stratify according status. Time trends multivariable logistic, Poisson linear regression models were applied. Results Overall,...
We hypothesized that the residency status (rural area [RA] vs urban clusters [UC] areas [UA]) affects stage and cancer-specific mortality (CSM) in contemporary newly diagnosed prostate cancer (PCa) patients of all stages, regardless treatment.Newly PCa with available were abstracted from Surveillance, Epidemiology, End Results database (2004-2016). Propensity-score (PS) matching, cumulative incidence plots, multivariate competing-risks regression (CRR) models used.Of 531,468 6653 (1.3%)...
Relative to urban populations, rural patients may have more limited access care, which undermine timely bladder cancer (BCa) diagnosis and even survival.We tested the effect of residency status (rural areas [RA < 2500 inhabitants] vs. clusters [UC ≥ urbanized [UA, ≥50,000 inhabitants]) on BCa stage at presentation, as well cancer-specific mortality (CSM) other cause (OCM), according US Census Bureau definition. Multivariate competing risks regression (CRR) models were fitted after matching...
The distribution of metastatic sites in upper tract urothelial carcinoma (UTUC) is not well-known. Consequently, the effects sex and age on location metastases also unknown. This study sought to investigate age- sex-related differences patients with UTUC.Within Nationwide Inpatient Sample database (2000-2015), we identified 1,340 UTUC. Sites metastasis were assessed according (≤63, 64-72, 73-79, ≥80 years) sex. Comparison was performed trend chi-square tests.Of UTUC, 790 (59.0%) men (median...
Abstract Objective Our objective was to investigate age- and sex-related differences in the distribution of metastases patients with metastatic bladder cancer. Methods Within National Inpatient Sample database (2008–2015), we identified 7040 Trend test Chi-square analyses were used evaluate relationship between age site metastases, according sex. Results Of cancer, 5226 (74.2%) men 1814 (25.8%) women. Thoracic, abdominal, bone brain present 19.5 vs. 23.0%, 43.6 46.9%, 23.9 18.7% 2.4 2.9%...
No AccessJournal of UrologyAdult Urology1 Nov 2020The Impact Race and Age on Distribution Metastases in Patients with Prostate CancerThis article is commented by the following:Editorial CommentEditorial Comment Lara Franziska Stolzenbach, Giuseppe Rosiello, Marina Deuker, Claudia Collà-Ruvolo, Luigi Nocera, Zhe Tian, Derya Tilki, Alberto Briganti, Fred Saad, Felix K. H. Chun, Markus Graefen, Pierre I. Karakiewicz StolzenbachLara Stolzenbach *Correspondence: Martini-Klinik Cancer Center,...
Abstract Background The United States Census Bureau recommends distinguishing between “Asians” vs. “Native Hawaiians or Other Pacific Islanders” (NHOPI). We tested for prognostic differences according to this stratification in patients with prostate cancer (PCa) of all stages. Methods Descriptive statistics, time-trend analyses, Kaplan–Meier plots and multivariate Cox regression models were used test at diagnosis, as well specific mortality (CSM) the Bureau’s definition either non-metastatic...
Misclassification rates defined as upgrading, upstaging, and upgrading and/or upstaging have not been tested in contemporary Black patients relative to White who fulfilled criteria for very-low-risk, low-risk, or favorable intermediate-risk prostate cancer. This study aimed address this void.Within the SEER database (2010-2015), we focused on with very low, intermediate risk cancer underwent radical prostatectomy had available stage grade information. Descriptive analyses, temporal trend...
Bladder cancer is the second most common genitourinary malignancy in United States. The incidence of bladder rises with age, and it two times more Caucasians than African-Americans (23.1 vs. 12.6 cases/100,000 persons). We aimed to investigate racial age-related differences distribution metastasis a large, contemporary cohort metastatic patients.Within National Inpatient Sample database (2008-2015) we identified 5,767 patients cancer. Trend test, Chi-square test multivariable logistic...
<b><i>Objective:</i></b> The aim of the study was to investigate differences in stage at presentation and cancer-specific mortality (CSM) between rural area (RA) urban (UA) residence status nonmetastatic upper urinary tract urothelial carcinoma (UTUC) patients. <b><i>Methods:</i></b> Newly diagnosed T<sub>1–3</sub>N<sub>0</sub>M<sub>0</sub> UTUC patients with available were abstracted from Surveillance,...