- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Radiopharmaceutical Chemistry and Applications
- Cancer, Lipids, and Metabolism
- Medical Imaging Techniques and Applications
- Genital Health and Disease
- Health Promotion and Cardiovascular Prevention
- Sexual function and dysfunction studies
- Urological Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Clinical practice guidelines implementation
- Advanced Radiotherapy Techniques
- Urinary Bladder and Prostate Research
- Viral-associated cancers and disorders
- Global Cancer Incidence and Screening
- MRI in cancer diagnosis
- COVID-19 and healthcare impacts
- PI3K/AKT/mTOR signaling in cancer
- Statistical Methods in Clinical Trials
- Genomics and Rare Diseases
- Male Reproductive Health Studies
St. Antonius Ziekenhuis
2020-2025
Erasmus University Rotterdam
2025
Erasmus MC
2025
University Medical Center Utrecht
2014-2024
Santeon (Netherlands)
2018-2023
No AccessJournal of UrologyAdult Urology1 Jul 2020Nerve Sparing during Robot-Assisted Radical Prostatectomy Increases the Risk Ipsilateral Positive Surgical Margins T. F. W. Soeterik, H. E van Melick, L. M. Dijksman, S. Stomps, J. A. Witjes, and P. Basten SoeterikT. Soeterik *Correspondence: Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands E-mail Address: [email protected] Department Value-Based Healthcare, Santeon, Utrecht, , MelickH. Melick Urology, St. Antonius Hospital,...
Bilateral extended pelvic lymph node dissection at the time of radical prostatectomy is current standard care if indicated; often, however, performed in pN0 disease. With more accurate staging achieved with magnetic resonance imaging-targeted biopsies for prostate cancer diagnosis, indication bilateral may be revised. We aimed to assess feasibility unilateral era modern imaging.We analyzed a multi-institutional data set men cN0 disease diagnosed by biopsy who underwent and dissection. The...
To assess the survival outcomes of adjuvant radiation therapy (aRT) versus observation with or without early salvage RT (Obs±esRT) for cN0M0 pN1 PCa and to create a model clinical decision making. We retrospectively identified 1,103 patients after surgery ( 2000-2021) at 18 referral centers. Kaplan-Meier curves, Cox proportional hazards were used. Overall, 670 (61%) had ISUP 4-5 median number positive nodes was 1. On multivariable analyses, ≥3 (HR 2.03,95% CI 1.22-3.37; p=0.006) 5 1.92,95%...
266 Background: We previously established prognostic nomograms of PSMA-PET standardized by Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE) criteria in a large single-center cohort. Now, we reassess the PROMISE (PPP) international multi-center registry study with overall survival follow-up. Methods: included patients histologically proven prostate cancer who underwent at 20 hospitals Germany, Italy, Sweden, Netherlands, Belgium, Slovakia, Austria, United States and...
To summarize the recent findings on subject of metastasis-directed therapy (MDT) in treatment oligometastatic prostate cancer (omPCa).
Current guidelines do not provide strong recommendations on preservation of the neurovascular bundles during radical prostatectomy in case high-risk (HR) prostate cancer and/or suspicious extraprostatic extension (EPE). We aimed to evaluate when, unilateral HR disease, contralateral nerve sparing (NS) should be considered or not.Within a multi-institutional data set we selected patients with cancer, defined as EPE seminal vesicle invasion (SVI) multiparametric (mp) magnetic resonance imaging...
Abstract Background Prebiopsy magnetic resonance imaging (MRI) increases the detection rate of clinically significant prostate cancer (csPCa). Prostate‐specific membrane antigen‐positron emission tomography/computed tomography (PSMA PET/CT) maximum standardized uptake value (SUVmax) may offer additional in predicting likelihood csPCa biopsy. Methods A single‐center cohort study involving patients with biopsy‐proven PCa who underwent both MRI and PSMA PET/CT between 2020 2021. Logistic...
Patients diagnosed with grade group (GG) 1 prostate cancer (PCa) following treatment for benign disease ("incidental" PCa) are typically managed active surveillance (AS). It is not known how their outcomes compare those observed in patients GG1 on biopsy. We aimed at determining whether long-term oncologic of AS PCa differ according to the type diagnosis: incidental versus biopsy detected.
To evaluate the impact of using clinical stage assessed by multiparametric magnetic resonance imaging (mpMRI) on performance two established nomograms for prediction pelvic lymph node involvement (LNI) in patients with prostate cancer.Patients undergoing robot-assisted extended dissection (ePLND) from 2015 to 2019 at three teaching hospitals were retrospectively evaluated. Risk LNI was calculated four times each patient, tumour (T-stage) digital rectal examination (DRE) and mpMRI, Memorial...