Hengchang Zang

ORCID: 0000-0003-2751-0281
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About
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Research Areas
  • Spectroscopy and Chemometric Analyses
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Traditional Chinese Medicine Analysis
  • Advanced Chemical Sensor Technologies
  • Analytical Chemistry and Chromatography
  • Water Quality Monitoring and Analysis
  • Metabolomics and Mass Spectrometry Studies
  • Chromatography in Natural Products
  • Mineral Processing and Grinding
  • Proteoglycans and glycosaminoglycans research
  • Pharmacological Effects of Natural Compounds
  • Traditional Chinese Medicine Studies
  • Meat and Animal Product Quality
  • Supramolecular Self-Assembly in Materials
  • Polydiacetylene-based materials and applications
  • Osteoarthritis Treatment and Mechanisms
  • Natural product bioactivities and synthesis
  • Crystallization and Solubility Studies
  • Fault Detection and Control Systems
  • Plant-based Medicinal Research
  • Essential Oils and Antimicrobial Activity
  • Analytical Methods in Pharmaceuticals
  • Protein Interaction Studies and Fluorescence Analysis
  • Phytochemicals and Antioxidant Activities
  • Bee Products Chemical Analysis

Shandong University
2016-2025

National Medical Products Administration
2021-2025

Yangzhou University
2024-2025

Shandong Provincial Hospital
2025

Shandong First Medical University
2025

Chinese Research Academy of Environmental Sciences
2025

Xinjiang Institute of Ecology and Geography
2022

Chinese Academy of Sciences
2022

ZheJiang Institute For Food and Drug Control
2013

Sun Chemical (United States)
2013

This study aims to evaluate the efficacy and therapeutic mechanism of bufalin on lung adenocarcinoma (LUAD) through a comprehensive strategy integrating network pharmacology, metabolomics molecular biology verification.The putative targets were discerned from PharmMapper Swiss Target Prediction database. LUAD-related obtained by target filtering GeneCard database data mining GEO PPI was constructed screen core targets, their clinical significance assessed several public databases. GO KEGG...

10.1016/j.compbiomed.2023.106777 article EN cc-by-nc-nd Computers in Biology and Medicine 2023-03-11

10.1016/j.saa.2019.117183 article EN Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 2019-05-28

Supramolecular peptide assemblies have been widely used for the development of biomedical, catalytical, and optical materials with chiral nanostructures in view intrinsic chirality peptides. However, assembly pathway transformation behavior various peptides remain largely elusive especially transient under out-of-equilibrium conditions. Herein, N-fluorenylmethoxycarbonyl-protected phenylalanine-tyrosine dipeptide (Fmoc-FY) was as a platform, which showed that proceeds multistep evolution....

10.1002/anie.202314368 article EN Angewandte Chemie International Edition 2023-11-08

Despite standard treatment for non-small cell lung cancer (NSCLC) being surgical resection, recurrence and complications, such as induction of malignant pleural effusion (MPE) significant postoperative pain, usually result in failure. In this study, an alginate-based hybrid hydrogel (SOG) is developed that can be injected into the resection surface lungs during surgery. Briefly, endoplasmic reticulum-modified liposomes (MSLs) pre-loaded with signal transducer activator transcription 3...

10.1016/j.ajps.2024.100925 article EN cc-by-nc-nd Asian Journal of Pharmaceutical Sciences 2024-05-03

Chondroitin sulfate (CS) plays important roles in the complement system. However, CS structure is complicated due to different sources and number positions of groups. The objective this study was prepare low molecular weight chondroitin sulfates (LMWCSs) investigate biological activity anti-complement capacity. A series LMWCSs prepared from characterized by ultraviolet-visible (UV) spectroscopy, high-performance liquid chromatography (HPLC), size exclusion chromatography-multiangle laser...

10.3390/ijms17101685 article EN International Journal of Molecular Sciences 2016-10-11

Abstract In order to understand the hydration effect of hyaluronic acid (HA) in aqueous solution, near-infrared (NIR) spectroscopy was used investigate HA solutions at different concentrations and temperature. As concentration raised, there a nonlinear change absorption value first overtone region OH, indicating changes water. A reconstructed spectrum based on principal component analysis (PCA) established analyzed with concept aquaphotomics. The results showed that acted as structure maker...

10.1038/s41598-020-58417-5 article EN cc-by Scientific Reports 2020-01-28

Confusing low-molecular-weight hyaluronic acid (LMWHA) from degradation and enzymatic hydrolysis (named LMWHA–A LMWHA–E, respectively) will lead to health hazards commercial risks. The purpose of this work is analyze the structural differences between then achieve a fast accurate classification based on near-infrared (NIR) spectroscopy machine learning. First, we combined nuclear magnetic resonance (NMR), Fourier transform infrared (FTIR) spectroscopy, two-dimensional correlated NIR (2DCOS),...

10.3390/molecules28020809 article EN cc-by Molecules 2023-01-13

A simple, sensitive and accurate method based on high performance liquid chromatography (HPLC) with diode array detector (DAD) was developed validated for systematic quality evaluation of one type traditional Chinese medicine preparations named Xinkeshu (XKS) tablet. In this study, the chromatographic fingerprints XKS tablet were first, 23 peaks selected as common to evaluate similarities among different batches samples, which manufactured in a long time span three years. Additionally,...

10.1016/j.jpha.2012.05.006 article EN cc-by-nc-nd Journal of Pharmaceutical Analysis 2012-06-18
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