- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Gaze Tracking and Assistive Technology
- Sleep and Wakefulness Research
- Neurological disorders and treatments
- Genomics and Rare Diseases
- Sleep and related disorders
- Neural dynamics and brain function
- Machine Learning in Healthcare
- Amyotrophic Lateral Sclerosis Research
- Biomedical Ethics and Regulation
- Brain Tumor Detection and Classification
- Advanced Memory and Neural Computing
- Neural and Behavioral Psychology Studies
- Circadian rhythm and melatonin
- Epilepsy research and treatment
- Restless Legs Syndrome Research
University of Tübingen
2019-2021
Shanghai Maritime University
2017
Abstract Patients in the transition from locked-in (i.e., a state of almost complete paralysis with voluntary eye movement control, blinks or twitches face muscles, and preserved consciousness) to total including eye-muscles loss gaze-fixation, combined are left without any means communication. An auditory communication system based on electrooculogram (EOG) was developed enable such patients communicate. Four amyotrophic lateral sclerosis completely state, ALSFRS-R score 0, unable use...
The dataset presented here contains recordings of electroencephalogram (EEG) and electrooculogram (EOG) from four advanced locked-in state (LIS) patients suffering ALS (amyotrophic lateral sclerosis). These could no longer use commercial eye-trackers, but they still move their eyes used the remnant oculomotor activity to select letters form words sentences using a novel auditory communication system. Data were recorded during variable range visits (from 2 10), each visit comprised 3.22 ±...
Persons in the completely locked-in state (CLIS) suffering from amyotrophic lateral sclerosis (ALS) are deprived of many zeitgebers circadian rhythm: While cognitively intact, they paralyzed, eyes mostly closed, with artificial ventilation and nutrition, social communication extremely restricted or absent. Polysomnographic recordings eight patients CLIS, however, revealed presence regular episodes deep sleep during night time all patients. It was also possible to distinguish an alpha-like a...
Abstract Persons with their eye closed and without any means of communication is said to be in a completely locked-in state (CLIS) while when they could still open eyes actively or passively have some are (LIS). Two patients CLIS communication, one patient the transition from LIS who Amyotrophic Lateral Sclerosis were followed at regular interval for more than 1 year. During each visit, resting-state EEG was recorded before brain–computer interface (BCI) based sessions. The analyzed...
Abstract To develop a more reliable brain–computer interface (BCI) for patients in the completely locked-in state (CLIS), here we propose Pavlovian conditioning paradigm using galvanic vestibular stimulation (GVS), which can induce strong sensation of equilibrium distortion individuals. We hypothesized that associating two different sensations caused by two-directional GVS with thoughts “yes” and “no” individuals would enable us to emphasize differences brain activity associated yes no hence...