This study aimed to evaluate the prognostic impact of permanent pacemaker (PPM) implantation within first year after mitral valve (MV) surgery combined with Cox-maze procedure, focusing on long-term outcomes, including overall mortality, infective endocarditis (IE) and ischaemic stroke. We conducted a retrospective cohort using data from National Health Insurance Service (NHIS) in South Korea, identifying 10 127 patients who underwent MV procedure between 2005 2020. Patients were classified...

This study was conducted to directly compare the effects of pulsatile and nonpulsatile blood flow in extracorporeal circulation upon renal tissue perfusion by using a measurement system. A total cardiopulmonary bypass circuit constructed accommodate twelve Yorkshire swine, weighing 20 approximately 30 kg. Animals were randomly assigned group 1 (n = 6, centrifugal pump) or 2 T-PLS pump). probe (Q-Flow 500) inserted into parenchymal tissue, maintained for an hour at pump rate L/min after...

Fe/NiO/MgO/Ag(001) films were grown epitaxially, and the Fe NiO spin orientations determined using x-ray magnetic dichroism. We find that spins are aligned perpendicularly to in-plane spins. Analyzing both out-of-plane components of layer, we demonstrate unambiguously antiferromagnetic undergo a continuous reorientation transition from directions with increasing MgO thickness.

The Twin-Pulse Life Support System (T-PLS) is a novel pulsatile extracorporeal life support system developed in Korea. It has been reported that the T-PLS achieves higher levels of tissue perfusion kidney during short-term circulation and provides more blood flow to coronary artery than nonpulsatile pumps. However, these results lack pulsatility quantifications thus make it hard analyze effects upon hemodynamic performance. We have adopted concepts energy, energy equivalent pressure (EEP),...

How much flow is required by a nonpulsatile pump to match the coronary blood equivalent that of pulsatile pump? A cardiopulmonary bypass circuit from right atrium ascending aorta was constructed in ventricular fibrillation model using 13 Yorkshire swine. The animals were randomly divided into two groups: CONTROL (pulsatile T-PLS, n = 7) or EXPERIMENTAL (nonpulsatile Biopump, 6). hemodynamic data at mid-LAD level measured with meter baseline and every 20 minutes after initiation. started 2...

Background In sudden cardiac arrest, the effective maintenance of coronary artery blood flow is paramount importance for myocardial preservation as well recovery and patient survival. The purpose this study was to directly compare effects pulsatile versus non-pulsatile circulation in a arrest condition. Methods A cardiopulmonary bypass circuit constructed ventricular fibrillation model using fourteen Yorkshire swine weighing 25–35 kg each. animals were randomly assigned group I (n=7,...

An extracorporeal life support system (ECLS) with a conventional membrane oxygenator requires driving force for the blood to pass through hollow fiber membranes. We hypothesized that if gravity-flow is installed in circuit, twin sacs of pulsatile ECLS (the Twin-Pulse Life Support, T-PLS) can be placed downstream oxygenator. This would increase pump output by doubling pulse rate at given pumpsetting while maintaining effective pulsatility. The purpose this study was determine optimal circuit...

We examined the pulsatility generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination in terms of energy equivalent pressure (EEP) and surplus hemodynamic (SHE). In five cardiac-arrested pigs, outflow cannula CP was inserted into ascending aorta, inflow right atrium. A 30-ml IABP subsequently placed descending aorta. Extracorporeal circulation maintained for 30 minutes using a flow 75 ml/kg per minute alone or IABP/CP with measured internal carotid artery. The...

We measured heating of isotonic saline by three fluid warmers in six experiments: at 5 °C or 20 delivered 30, 50 100 ml.min−1. At the flow rates, enFLOW®, buddy lite™ and ThermoSens® systems heated to mean (SD) temperatures of: 41.1 (0.5) °C, 37.7 (0.6) 39.1 °C; 40.3 (0.8) 33.9 (1.6) 39.3 (0.7) 37.1 24.0 (1.3) 37.6 (1.0) respectively, p < 0.0001 for each experiment. The times taken heat were: 16.6 (1.7) s, 258.4 (58.9) s 134.2 (79.6) s; 16.9 (1.8) 256.2 (62.2) 182.5 (74.5) 21.5 (1.5) 275.9...

At his final admission, 2 years after MVR, he returned for fever and oliguria of nearly weeks' standing.Routine blood tests showed the total number leukocytes to be 2. 3 10 9 cells/L.Neutrophil ratio was 78.3%, eosinophilic count normal.The serum creatinine value 142 mmol/L.TTE bioprosthetic valve in good condition; however, left ventricular apex attached with a single hyperechoic group about 1 cm diameter.It had significant activity (Figure 2,C).This time, infective endocarditis...

Most patients needing implantation of a ventricular assist device (VAD) require repeated sternotomy; some after cardiac surgery, and others later for heart transplantation. The purpose this study was to establish the right thoracotomy technique as an alternative VAD reduce sternotomy-related morbidity mortality. We performed in animals, preclinical cadaver fitting tests, clinical case. A total 20 various animals underwent bi-VAD (BVAD, n = 17) left (LVAD, 3). chest cavity entered through...

We compared the coronary artery blood flow and hemodynamic energy between pulsatile extracorporeal life support (ECLS) a centrifugal pump (CP)/intra-aortic balloon (IABP) combination in cardiac arrest. A total cardiopulmonary bypass circuit was constructed for six Yorkshire swine weighing 30 to 40 kg. The outflow cannula of CP or ECLS (T-PLS) inserted into ascending aorta, inflow T-PLS placed right atrium. 30-ml IABP subsequently descending aorta. Extracorporeal circulation maintained...

Background Despite advance in off-pump coronary artery bypass (OPCAB) grafting, there are large debating issues regarding survival benefit between OPCAB and on-pump grafting (CABG). The aim of this study is to address appropriateness approach patients with ischemic heart disease having multiple vessels using South Korea national cohort data. Methods To evaluate the safety efficacy OPCAB, we accessed all causes death, late repeat revascularization, hospitalization for cerebrovascular accident...

Ho Sung Son, M.D., Lee, Laleng Mawia Darlong, M.S., Jae Seong Jung, Kyung Sun, Kwang Taik Kim, Hee Jung Kanghoon Seung Hun and Jong Tae Lee. Korean J Thorac Cardiovasc Surg 2014;47:124-8. https://doi.org/10.5090/kjtcs.2014.47.2.124

In this study, we developed a small pneumatic actuator that can be used as an extracorporeal biventricular assist device. It incorporated bellows-transforming mechanism to generate blood-pumping pressure. The cylindrical unit is 88 +/- 0.1 mm high, has diameter of 150 mm, and weighs 2.4 0.01 kg. vitro, maximal outflow at the highest pumping rate (PR) exceeded 8 L/min when two 55 mL blood sacs were under afterload pressure 100 Hg. At beats per minute (bpm), hydraulic efficiency was 9.34%...

Abstract To evaluate the performance and safety of a newly developed blood warmer ( T hermo S ens), we tested its heating capability under various conditions using isotonic saline hemolysis analysis with swine blood. The following two in vitro tests were performed: (i) investigate device, inflow outflow temperatures measured at flow rates (30, 50, 100 mL/min) cold (5°C) room temperature (20°C) (0.9%). Several parameters including highest outlet, time required to reach temperature,...

Extracorporeal membrane oxygenation (ECMO) has become increasingly accepted as a life-saving procedure for patients with severe acute respiratory distress syndrome (ARDS). This study investigated the relationship between cumulative fluid balance (CFB) and outcomes in adult ARDS treated ECMO.We retrospectively analyzed data of who received ECMO December 2009 2019 at Korea University Anam Hospital. CFB was calculated during first 7 days after initiation. The primary endpoint 28-day...

Background: A substantial proportion of cardiac arrhythmias are paroxysmal in nature, and 12-lead electrocardiography (ECG) Holter monitoring often fail to detect arrhythmias. We designed evaluated a watch-type, electrocardiograph-recording, wearable device (w-ECG) overcome the limitations ECG monitoring. Methods: prospectively enrolled 96 patients with symptoms assumed be related Electrocardiography recording was performed both w-ECG Detection any arrhythmia primary outcome endpoint...

We examined the relationship between blood transfusion and long-term adverse events to evaluate clinical impact of red cell (RBC) on patients undergoing cardiac valve surgery.From National Health Insurance Service database, individuals heart surgery were verified, including aortic (AV), mitral (MV), tricuspid (TV), complex valves (more than 2 surgeries). The interested outcomes incidence death, ischemic stroke, hemorrhagic admission for myocardial infarction during follow-up. Associations...

Blood viscosity during operation of ventricular assist device (VAD) can be changed by various conditions such as anemia. It is known generally that the blood affect vascular resistance and lead to change flow. In this study, effect fluid variation on hemodynamic energy was evaluated with a pulsatile pump in mock system. Six solutions were used for experiments, which composed water glycerin had different viscosities 2, 2.5, 3, 3.5, 4, 4.5 cP. The at outlet cannula measured. Experimental...

Percutaneous placement of extracorporeal membrane oxygenation (ECMO) cannulas has many benefits. However, limb ischaemia still remains as an unresolved problem. We experienced interesting case that was caused by external compression the superficial femoral artery venous cannula. A 73-year old woman underwent veno-arterial ECMO due to sudden cardiac arrest with percutaneous cannulations at right common vein and left artery. Three hours after cannulation, patient's lower extremity cool pale,...

Abstract: Nonpulsatile blood pumps are mainly used in extracorporeal life support systems. Although pulsating flow is known to be physiological, a pulsatile pump not commonly applied circuit with membrane oxygenator because of damage the cells. The hypothesis that placement pressure‐relieving compliance chamber might reduce cell trauma was tested. An constructed an acute lung injury model dogs by oleic acid infusion. animals were divided into three groups. In group I ( n = 6) nonpulsatile...

Abstract The bellows‐type pneumatic ventricular assist device (VAD) generates pressure with compression of bellows instead using an air compressor. This VAD driver has a small volume that is suitable for portable devices. However, improper setup can not only cause lack adequate flow generation, but also durability problems. In this study, regulation system optimal operation the been developed. conditions according to various afterload aiming rates were investigated, and estimation algorithm...