Skin ageing is an inevitable process characterized by loss of elasticity and decreased dermal volume. Nanofat injection a new technique used for long-lasting skin rejuvenation, while hyaluronic acid (HA) widely to improve rejuvenation temporarily. This work aimed compare the effect nanofat versus subcutaneous injections on aged thin female rats. Four equal groups 40 rats were included in this study. Group I (GpI) was control adult, GpII one. GpIII received single (SC) 0.1 ml cross-linked HA,...

Abstract: Methotrexate (MTX) is a drug used in treatment of various malignancies. Unfortunately, it leads to life-threatening complications including hepatorenal toxicity. Previous studies revealed the protective effects metformin (MET) on toxicity other models addition its anticancer effects. The current study investigates effect MET MTX-induced and possible mechanisms involved this which can be overwhelmed by MET. Thirty male rats were divided into 3 groups: normal control, MTX treated...

Lactoferrin (LF) was previously suggested to have a protective effect against liver fibrosis by preventing hepatic stellate cells (HSCs) activation. The of LF on heat shock protein 47 (HSP47) has not yet been studied so this study designed investigate HSP47 as potential target for management and comparing it with silymarin (SM) in thioacetamide (TAA)-induced model. Rats were divided into four groups; normal control, TAA (TAA-treated), (LF + TAA-treated), SM (SM TAA-treated). After 6 weeks,...

Ethylene glycol is an alcohol widely used in industry as antifreeze. It affects the normal gastric mucosal defense mechanisms, inducing surface ulcerations. L-arginine a precursor of nitric oxide that exhibits multiple biological properties; among them acceleration wound healing, especially stomach. Caspase-3 immunohistochemistry, and semithin ultrathin section examinations were to investigate possible protective effect on ethylene glycol-induced damage rats. Three animal groups used: group...

You have accessJournal of Urology1 Apr 2008EVALUATION OF THE CHEMOPROTECTIVE ROLE N-ACETYLCYSTEINE AGAINST CISPLATIN-INDUCED NEPHROTOXICITY: NEW ASPECT AN OLD DRUG Magdy A Sabaa, Amany Abdin, Eman Draz, and Naglaa Sarhan SabaaMagdy Sabaa More articles by this author , AbdinAmany Abdin DrazEman Draz SarhanNaglaa View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)60338-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked...

Muscle injuries present frequently in sports medicine. Healing with conventional therapy is often inadequate, leading to incomplete functional recovery due fibrosis. Generating substantial interest the potential for emerging technologies such as platelet-rich plasma (PRP) enhance soft-tissue healing and decrease time of became mandatory. The aim this work was evaluate role PRP promoting experimentally induced skeletal muscle injury adult male albino rat model. 48 rats were used divided into...

Introduction Fibronectin is an extracellular matrix glycoprotein that binds to membrane receptor integrin and components such as collagen, fibrin, heparin sulfate proteoglycans. It plays a major role in cell adhesion, growth, migration, differentiation, it important for processes wound healing embryonic development. Altered fibronectin expression, degradation, organization have been associated with number of pathologies including cancer fibrosis. Aim the study This was conducted evaluate...

Introduction Carbon tetrachloride (CCl4) has long been known as a model toxicant. Antioxidants are used to antagonize the deleterious action of free radicals. Numerous reports suggest that both curcumin and ginger have antioxidant effects. Aim work This was carried out compare between possible protective roles on renal corpuscles CCl4-treated adult male albino mice using light electron microscopes. Materials methods A total 45 were for this study divided into four groups: group I served...

Abstract Background Chemotherapy-induced cardiomyopathy (CIC) is a common side effect affecting patients with breast cancer treated anthracyclines chemotherapeutic agents. Vitamin D receptor gene polymorphism seemed to play crucial role in developing CIC, as vitamin deficiency was found increase the risk of many diseases including colon, breast, prostate and ovarian cancer. Purpose The current study primarily investigate (ApaI, TaqI, BsmI FokI) on incidence CIC adult local/advanced or...

An atrophic scar is a prevalent cosmetic condition. It happens as result of diminished production connective tissue, and inadequate compensation dermal collagen that throughout the process tissue regeneration following injuries. Various techniques may be employed for dealing with scars, including subcision, peeling chemicals, dermabrasion, punch grafting, application filler materials to improve depressed areas. Subcision, or subcutaneous incisionless operations, kind surgery targets various...