N. Takahashi

ORCID: 0000-0003-2775-1712
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Research Areas
  • Synthetic Organic Chemistry Methods
  • Algebraic Geometry and Number Theory
  • Catalytic Alkyne Reactions
  • T-cell and B-cell Immunology
  • Stability and Control of Uncertain Systems
  • Homotopy and Cohomology in Algebraic Topology
  • Studies on Chitinases and Chitosanases
  • Statistical and numerical algorithms
  • Enzyme Production and Characterization
  • Synthesis and Characterization of Heterocyclic Compounds
  • Cell Adhesion Molecules Research
  • Advanced Control Systems Optimization
  • Chemokine receptors and signaling
  • Synthesis and Reactions of Organic Compounds
  • Cybersecurity and Information Systems
  • Biofuel production and bioconversion
  • Phytochemical compounds biological activities
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Bioactive Compounds and Antitumor Agents
  • Formal Methods in Verification
  • nanoparticles nucleation surface interactions
  • Synthesis of heterocyclic compounds
  • Scientific Research and Discoveries
  • Advanced Algebra and Geometry
  • Advanced Synthetic Organic Chemistry

Kyoto University
1993-2020

University of Miyazaki
2003-2017

Kaken Pharmaceutical (Japan)
2011

Nihon University
2009

Nagoya University
1974

A direct, concise, and atom-economical synthetic method for the generation of fused indoles, using a gold-catalyzed cascade cyclization diynes, has been developed. The reaction gave various such as aryl-annulated[a]carbazoles, dihydrobenzo[g]indoles, azepino- or oxepinoindole derivatives in good to excellent yields, through an intramolecular 5-endo-dig hydroamination followed by 6- 7-endo-dig cycloisomerization, without producing theoretical byproduct. Three resulting indoles exhibited...

10.1021/jo102507c article EN The Journal of Organic Chemistry 2011-01-21

Chitinase from T. kodakarensis (TkChiA) catalyzes the hydrolysis of chitin. The enzyme consists two catalytic and three binding domains (ChBD1, ChBD2 ChBD3). ChBD3 can bind to not only chitin but also cellulose. In both domains, intervals side chains tryptophan residues, which are located on molecular surface, correspond twice length lattice A model with crystalline implies that residues a glutamate residue interact hexose ring by CH-π interactions amide group hydrogen bond, respectively.

10.1002/1873-3468.12055 article EN FEBS Letters 2016-01-01

10.1007/bf00935607 article EN Journal of Optimization Theory and Applications 1974-01-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Potential Anticancer Agents. IX. Lawsone Derivatives Containing an Alkylating Function1,2W. R. VAUGHAN, M. S. HABIB, McELHINNEY, N. TAKAHASHI, and J. A. WATERSCite this: Org. Chem. 1961, 26, 7, 2392–2396Publication Date (Print):July 1, 1961Publication History Published online1 May 2002Published inissue 1 July 1961https://pubs.acs.org/doi/10.1021/jo01351a059https://doi.org/10.1021/jo01351a059research-articleACS PublicationsRequest reuse...

10.1021/jo01351a059 article EN The Journal of Organic Chemistry 1961-07-01

The authors propose a novel fault simulation technique for multiple faults. In order to handle large number of faults, sets faults are represented by Boolean functions, in which shared binary decision diagrams (BDDs) used as an internal representation functions. also dropping method, prime dropping, is efficiently execute simulation. have succeeded simulating 39 million double circuit 2300 gates with about 20 Mbyte storage.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML"...

10.1109/iccad.1991.185329 article EN 2002-12-10

This note extends guaranteed cost control based on the linear upper bound to case with cross product terms in performance index and shows that design problem can result solvability of stochastic algebraic Riccati equation (SARECP). It is shown there exists a solution under stabilizability, detectability assumption system perturbations are not too large.

10.1109/sice.2002.1195211 article EN 2003-12-22

Abstract A new method to prepare diverse fused indoles as well naphthofuran derivatives is reported.

10.1002/chin.201123108 article EN ChemInform 2011-05-12

We synthesized C8-vinylpyrene-substituted 2′-deoxyguanosine VPyG and studied the photoinduced reversible E–Z isomerization. When E-isomer was irradiated with visible light (>420 nm), E- to Z-isomerization took place very rapidly, while upon irradiation UV-light (∼365 Z-isomer converted E-isomer. illuminated 365– 400 nm light, no fluorescence observed, showed a strong emission, indicating that could be useful switching molecule.

10.1093/nass/nrp097 article EN Nucleic Acids Symposium Series 2009-09-01

For an algebraic number field $K$ and a prime $p$, let $\widetilde{K}/K$ be the maximal multiple $\mathbb{Z}_p$-extension. Greenberg's generalized conjecture (GGC) predicts that Galois group of unramified abelian pro-$p$ extension $\widetilde{K}$ is pseudo-null over completed ring $\mathbb{Z}_p[\![\mathop{\mathrm{Gal}}\nolimits(\widetilde{K}/K)]\!]$. We show GGC holds for some imaginary quartic fields containing quadratic numbers.

10.48550/arxiv.2001.11768 preprint EN other-oa arXiv (Cornell University) 2020-01-01

For an algebraic number field [Formula: see text] and a prime text], let be the maximal multiple text]-extension. Greenberg’s generalized conjecture (GGC) predicts that Galois group of unramified abelian pro-[Formula: extension is pseudo-null over completed ring text]. We show GGC holds for some imaginary quartic fields containing quadratic numbers.

10.1142/s1793042121500305 article EN International Journal of Number Theory 2020-09-23

Abstract Die cyclischen Ketone (I) liefern nach Umsetzung mit Li‐Alkoholaten (II) und CS 2 die β‐Ketodithiocarboxylate (III), Methyliodid (IV) in Abhängigkeit von der Substitution entweder zu den Dithiooarbonsäureestern (V) oder α‐Ketoketendithioacetalen (VI) weiterreagieren.

10.1002/chin.198226131 article DE Chemischer Informationsdienst 1982-06-29
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