A5079543628- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Clinical Nutrition and Gastroenterology
- Organ Transplantation Techniques and Outcomes
- Management of metastatic bone disease
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Renal Transplantation Outcomes and Treatments
- Organ and Tissue Transplantation Research
- Neurofibromatosis and Schwannoma Cases
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Liver physiology and pathology
- Spinal Dysraphism and Malformations
- Bone Tumor Diagnosis and Treatments
- Spinal Hematomas and Complications
- Trauma Management and Diagnosis
- Pelvic and Acetabular Injuries
- Liver Disease and Transplantation
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Pituitary Gland Disorders and Treatments
- Transplantation: Methods and Outcomes
- Brain Metastases and Treatment
- Abdominal Surgery and Complications
North Bristol NHS Trust
2023
Clinique de Genolier
2019-2022
GenISys (Germany)
2022
University of Lausanne
2014-2020
University Hospital of Lausanne
2006-2019
Hôpital Orthopédique de la Suisse Romande
2008-2018
University of California, Los Angeles
2015
École Polytechnique Fédérale de Lausanne
2011
American College
2009
Society of Critical Care Medicine
2009
Background: The Institute of Medicine calls for the use clinical guidelines and practice parameters to promote "best practices" improve patient outcomes. Objective: 2007 update 2002 American College Critical Care Clinical Guidelines Hemodynamic Support Neonates Children with Septic Shock. Participants: Society members special interest in neonatal pediatric septic shock were identified from general solicitation at Educational Scientific Symposia (2001–2006). Methods: Pubmed/MEDLINE literature...
This retrospective study critically analyzed the long-term functional outcomes and tumor recurrence rates for surgically treated craniopharyngiomas.This used an outcome classification system that included functioning vision, independent versus dependent living, Karnofsky Performance Scale scores, academic levels, work status, psychological status. Tumor were with respect to extent of surgical resection adjunctive radiotherapy.For 121 patients, a mean follow-up period 10 years, overall "good...
Abstract OBJECTIVE The goal of this report is to illustrate the use radial artery grafts as bypass conduits in management complex intracranial aneurysms and describe a new “pressure distension technique” eliminate postoperative vasospasm, which was common problem early our experience. METHODS This study included series 17 patients who were surgically treated between 1994 January 2001 for aneurysms. Five without pressure technique; 12 patients, technique used reduce vasospasm. Fourteen had...
With advances in microsurgery and molecular biology, the mouse model for organ transplantation has become increasingly popular. However, knowledge about these models is limited, as only a small number of centers have experience with murine models. In this study, we compared rejection pattern after liver, kidney, heart, bowel three different strain combinations: (1) C57BL/6 (H2b)-->BALB/c (H2d), (2) BALB/c (H2d)-->CBA (H2k), (3) C57BL/6-->C3H/HeN (H2k). Our study demonstrated that allograft...
Improved microsurgical techniques for kidney transplantation in the mouse are described. Left renal is performed with end-to-side anastomoses of donor vein to inferior vena cava and aortic cuff aorta. Urinary tract reconstruction accomplished by suturing ureter a bladder patch recipient bladder. With these modifications, it possible achieve success rates as high 90%. This stable reproducible model provides useful tool study immunological mechanisms allograft rejection at molecular level.
In addition to its role in absorbing nutrients, the intestinal mucosa provides an important barrier against toxins and bacteria bowel lumen. The present study evaluated gut function following orthotopic (in continuity) grafting rats. Graft histology, permeability, bacterial translocation grafted mesenteric lymph nodes, host's liver, spleen were assessed on 3rd, 5th, 7th postoperative days. group received no immunosuppression after allotransplantation. two control groups included rats with...
Abstract Unlike other solid organ transplants, intestinal transplantation (IT) remains a highly experimental procedure. Rejection, sepsis, and graft‐versus‐host disease have been the major barriers to successful IT in humans. These problems can be studied rat model, but this requires reliable surgical technique that will produce high survival rates excellent graft function. Herein, we review 400 consecutive rats describe important technical aspects of surgery. Technical modifications helped...
To date, it has not been possible to reliably prevent intestinal allograft rejection in large animals. This study was undertaken determine if continuous i.v. cyclosporine (CsA) followed by p.o. CsA would outbred piglets with orthotopic, in-continuity allografts. Untreated recipients (n=7) died of (2), interstitial pnuemontitis (3), or technical complications (2) at 5.3±1 days. Intestinal treated 8 mg/kg/day and steroids (n=3) (mean survival 11.3±3.2 days). 20 plus for 21 days, 25 (n=6)...
No AccessJournal of Urology1 Apr 1950Cysto-Urethrography: its Role in Diagnosis neurogenic Bladder* Charles Ney, and John Duff NeyCharles Ney More articles by this author , DuffJohn View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)68809-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1950 The American Urological Association Education Research, Inc.FiguresReferencesRelatedDetailsCited ByBACHELARD M,...
ZHONG, ROBERT; HE, GANG; SAKAI, YOSHIHARU; LI, XIAN-CHANG; GARCIA, BERTHA; WALL, WILLIAM; DUFF, JOHN; STILLER, CALVIN; GRANT, DAVID Author Information
In contemporary surgical clinical practice, spinal instability is often treated with mechanical stabilization techniques in order to protect the cord and nerve roots. These involve placing screws defined regions of vertebrae, typically pedicle, where strongest bone found. The challenge for surgeon accurate placement good purchase avoid damage surrounding vital anatomical structures. This especially critical cervical region, target mass smaller cord, roots vertebral arteries are all at risk....
OBJECTIVE The goal of this report is to illustrate the use radial artery grafts as bypass conduits in management complex intracranial aneurysms and describe a new "pressure distension technique" eliminate postoperative vasospasm, which was common problem early our experience. METHODS This study included series 17 patients who were surgically treated between 1994 January 2001 for aneurysms. Five without pressure technique; 12 patients, technique used reduce vasospasm. Fourteen had anterior...
Two surgical techniques are commonly used for small intestinal transplantation: heterotopic (accessory) grafting (HIT), where the bowel is initially defunctioned with restoration of continuity at a later date, and orthotopic (in continuity) (OIT), immediately anastomosed to native intestine. The present experiments were undertaken compare advantages disadvantages these two models. Graft barrier function (intestinal permeability), histology, graft survival evaluated after transplantation in...
Abstract OBJECTIVE AND IMPORTANCE Invasion of trigeminal and facial perineural spaces is a recognized complication cutaneous malignancies. Centripetal spread along the nerve axis into cavernous sinus gasserian ganglion rare. Metastasis to leptomeninges cauda equina has not been reported. We report unique case central dissemination from an epithelial squamous cell carcinoma (SCC) associated with tumor biomarker. CLINICAL PRESENTATION After excision multiple SCCs basal carcinomas head neck,...
Intracranial hypotension is a rare, and possibly underrecognized, cause of headache in middle age. Occurring spontaneously the vast majority cases, it has been occasionally reported after certain neurosurgical procedures involving craniectomy. We report unique situation which patient developed severe postural typical intracranial hypotension, was complicated by bilateral subdural hematomas, immediately following routine lumbar diskectomy; resolved spontaneously. suggest that an...
Abstract We have recently developed a mouse intestinal transplantation model. The proximal segment of donor jejunum is transplanted into the recipient in heterotopic position. End‐to‐side anastomoses are performed between aorta and portal vein inferior vena cava. Mortality rates were initially high due to shock, arterial thrombosis, postoperative sepsis. Refinements surgical techniques reduced these complications, resulting rate success. Important technical factors included (1) minimizing...
Graft-versus-host disease was studied on the 10th and 14th postoperative days in Lewis x Brown Norway F1 rats (LBN-F1) receiving accessory heterotopic intestinal allografts. LBN-F1 isograft recipients were used as controls. The injected with sheep erythrocytes five before sacrifice. Rats graft-versus-host had progressive loss of normal architecture lymphoid organs. Skin, liver, colon, salivary glands infiltrated immunoblasts patchy areas necrosis. Concurrent these changes, there significant,...
GRANT, DAVID; SOMMERAUER, JOHN; MIMEAULT, RICHARD; GARCIA, BERTHA; GHENT, CAMERON; ZHONG, ROBERT; STILLER, CALVIN; DUFF, JOHN Author Information