A5066204700- Connective tissue disorders research
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Vascular anomalies and interventions
- Intraocular Surgery and Lenses
- Cardiovascular Issues in Pregnancy
- Trauma Management and Diagnosis
University of Oslo
2018-2020
Oslo University Hospital
2018-2019
Sunnaas sykehus
2019
Abstract Background To explore survival, causes of death, and the prevalence cardiovascular events in a Norwegian Marfan syndrome (MFS) cohort. MFS is heritable connective tissue disorder associated with reduced life expectancy–primarily due to aortic pathology. Methods A follow‐up study 84 adults, initially investigated 2003–2004. In 2014–2015, 16 were deceased, 47 68 survivors consented new clinical investigations. Analyses performed for deceased at follow‐up. Standardized mortality ratios...
Long-term follow-up of Marfan syndrome (MFS) patients.Investigate changes in ocular features MFS patients fulfilling the Ghent-2 criteria following a period 10 years.Repeated cross-sectional study with two observations.Eighty-four were investigated 2003-2004 (baseline). Forty-four these (52%) examined after years.A comprehensive examination performed at baseline and follow-up.Development or progression ectopia lentis (EL).At follow-up, mean age was 50.1 ± 11.9 years (range: 30-80 years), 74%...
Abstract The age‐dependent penetrance of organ manifestations in Marfan syndrome (MFS) is not known. aims this follow‐up study were to explore how clinical features change over a 10‐year period the same Norwegian MFS cohort. In 2003–2004, we investigated 105 adults for all 1996 Ghent nosology. Ten years later, performed investigations survivors ( n = 48) who consented. Forty‐six fulfilled revised criteria. Median age: females 51 years, range 32–80 years; males 45 30–67 years. New aortic root...
Abstract Background Marfan syndrome, a rare hereditary connective tissue disorder caused by mutations in fibrillin-1, can affect many organ systems, especially the cardiovascular system. Previous research has paid less attention to health-related quality of life and prospective studies on this topic are needed. The aim study was assess changes after 10 years Norwegian syndrome cohort. Methods Forty-seven patients ≥ 18 were investigated for all manifestations 1996 Ghent nosology completed...