A5033998037- Neurogenetic and Muscular Disorders Research
- Diet and metabolism studies
- Congenital Anomalies and Fetal Surgery
- Obesity, Physical Activity, Diet
- RNA modifications and cancer
- Child Nutrition and Feeding Issues
- Diet, Metabolism, and Disease
- Nutritional Studies and Diet
- Long-Term Effects of COVID-19
- Cystic Fibrosis Research Advances
- Adipose Tissue and Metabolism
- Nutrition and Health in Aging
- Sleep and related disorders
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- Metabolism and Genetic Disorders
- Telemedicine and Telehealth Implementation
- Circadian rhythm and melatonin
- Metabolism, Diabetes, and Cancer
- Dietary Effects on Health
- Clinical Nutrition and Gastroenterology
- Liver Disease Diagnosis and Treatment
- Consumer Attitudes and Food Labeling
- Child Nutrition and Water Access
- Vestibular and auditory disorders
University of Milan
2018-2025
IRCCS Istituto Auxologico Italiano
2023-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2025
Fondazione IRCCS Istituto Neurologico Carlo Besta
2019
As the coronavirus pandemic spreads, more and people are infected with severe acute respiratory syndrome 2. The short- medium-term effects of infection have been described, but description long-term sequelae is lacking in literature.Patients healed from disease 2019 (COVID-19) February 2020 to May were considered for inclusion this study, regardless severity during phase. Eligible patients consecutively contacted a semistructured interview was administered between March 2021 by trained...
The relationship between SARS-CoV-2 infection and dizziness is still unclear. aim of this study to assess the prevalence characteristics vertigo among patients with mild-to-moderate COVID-19. Patients discharged from emergency rooms a confirmed diagnosis were assisted by daily telephone calls until nasopharyngeal swab negativization, specific symptoms concerning balance disorders investigated through targeted questions posed experienced physicians. included 1512 subjects (765 females, 747...
Both abdominal obesity and its visceral component are independently associated with cardiometabolic diseases. Among the non-modifiable modifiable determinants, lifestyle plays a central role, while chronotype is an emerging factor. Evening type (E-Type), more active efficient in last part of day, has been health-impairing style, resulting higher risk diseases than morning (M-Type). However, no study examined contribution to fat distribution, even considering adherence Mediterranean diet...
Abstract Background Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by muscle and weakness. SMA type 1 (SMA1) the most severe form: affected infants are unable to sit unaided; 2 (SMA2) children can sit, but not able walk independently. The Standards of Care has improved quality life increasing availability disease-modifying treatments progressively changing natural history; so, clinical assessment nutritional status become even more crucial. Aims this multicenter...
The question whether the new cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs aimed at restoring CFTR protein function might improve glucose metabolism is gaining attention, but data on effect of lumacaftor/ivacaftor treatment (LUMA/IVA) tolerance are limited. We evaluated variation in and insulin secretion CF patients homozygous for Phe508del mutation after one-year with LUMA/IVA comparison to same genotype who did not receive such treatment.We performed a...
Inadequate sleep quality is a significant risk factor for overweight and obesity, which in turn may predispose individuals to adverse health outcomes. The aim of the present study was evaluate moderating effect physical activity on relationship between BMI adults with obesity. In current cross-sectional study, 589 white European participants (mean age 50 ± 12.2 years; 65% women; mean 31.4 5.5 kg/m 2 ) were recruited from International Center Assessment Nutritional Status Italy October 2021...
Abstract Objective Impaired metabolic flexibility is associated with prediabetes. However, its assessment reference methods impractical in routine clinical practice. This study investigates the relationship between fasting respiratory exchange ratio (RER), measured through indirect calorimetry, and glucose metabolism individuals Methods The involved two cohorts: 1) a cross-sectional cohort of 10,176 to assess association RER parameters 2) matched longitudinal 86 patients impaired glucose,...
Introduction: The relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and thyroid hormones has been established, but the direct effects of TSH on liver, potentially leading to steatosis, insulin resistance remain unclear. Objective: To investigate association levels with MASLD resistance. Methods: We conducted a cross-sectional study 8825 euthyroid individuals. Subjects were volunteers or patients referred International Center for Nutritional Status...
Men are more likely than women to have subthreshold overeating disorders. Lifestyle plays a role as determinant, while chronotype is an emerging factor. Chronotype explains the natural preferences of wakefulness and activity throughout day: evening chronotypes (E-Types), those most productive in evening, been linked with unhealthy dietary patterns higher propensity substance addiction morning types (M-Types).We carried out cross-sectional study on 750 overweight or obese adults (70% females,...
Objective: Few data are available on the Italian elderly population with regard to adherence Mediterranean diet (MD) and cognitive impairment. Our aim was investigate MD its association function in an urban sample.Methods: A cross-sectional study of 279 participants aged ≥ 65 years (80 men, 199 women) carried out at a nutritional center. Adherence evaluated using 14-item questionnaire. Cognitive assessed Mini-Mental State Examination (MMSE).Results: The clinical assessments performed...
The classical ketogenic diet (cKD) is an isocaloric, high fat, very low-carbohydrate that induces ketosis, strongly influencing leptin and ghrelin regulation. However, not enough known about the impact of a long-term cKD. This study evaluated effects 12-month cKD on concentrations in children, adolescents adults affected by GLUT1-Deficiency Syndrome or drug resistant epilepsy (DRE). We also investigated relationship between nutritional status, body composition variations. carried out...
The classic ketogenic diet (KD) is a high-fat, low-carbohydrate that mimics starvation state with sufficient caloric intake to sustain growth and development. KD an established treatment for several diseases, it currently evaluated in the management of insulin-resistant states, although insulin secretion after meal has never been investigated. We measured 12 healthy subjects (50% females, age range 19–31 years, BMI 19.7–24.7 kg/m2) cross-over administrations Mediterranean both satisfying...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic found Italy unprepared to cope with the large concentrated numbers of patients infected disease 2019 (COVID-19) who often required hospital admission and in many cases intensive care. This very quickly overwhelmed Italian Healthcare System. paper describes Active Home Surveillance System (Operations Center for Discharged Patients; COD19) Hospital Care (COD20) presents clinical data collected level user satisfaction...
We aimed to investigate the correlation between body composition (BC) and spinal muscular atrophy (SMA)-specific motor function assessments.Patients with SMA types I or II, aged 1 10 years, were recruited in this cross-sectional study. The protocol included anthropometric measurements, dual-energy X-ray absoprtiometry assess fat mass (FM), lean (LM), fat-free (FFM), FM FFM indexes (FMI, FFMI), assessments (Children's Hospital of Philadelphia Infant Test Neuromuscular Disorders scale for...
The classic ketogenic diet (cKD) is an isocaloric, high fat, low-carbohydrate that induces the production of ketone bodies. High consumption dietary fatty acids, particularly long-chain saturated could impair nutritional status and increase cardiovascular risk. purpose this study was to evaluate long-term effects a 5-year cKD on body composition, resting energy expenditure, biochemical parameters in children affected by Glucose Transporter 1 Deficiency Syndrome (GLUT1DS).This prospective,...
Spinal muscular atrophy (SMA) is a neuromuscular disease associated with nutritional status derangement and altered body composition. New drugs are changing the natural history of disease, so now more than ever important to focus on correct assessment in SMA. We implemented standardization process for anthropometric measurement as part our ongoing longitudinal study growth patterns SMA patients. It features procedural manual, included this communication, observers training reliability...
Differences in body fat distribution may be a reason for the sex-, age-, and ethnicity-related differences prevalence of fatty liver disease (FL). This study aimed to evaluate sex- age-related contribution visceral (VAT) subcutaneous (SAT) abdominal fat, measured by ultrasound, index (FLI) large sample overweight obese Caucasian adults, identify VAT SAT cut-off values predictive high FL risk. A cross-sectional on 8103 subjects was conducted. Anthropometrical measurements were taken...