About
Contact & Profiles
A5017240491
Research Areas
- Genomics and Chromatin Dynamics
- Chromosomal and Genetic Variations
- Pluripotent Stem Cells Research
Center for Excellence in Molecular Cell Science
2023
University of Chinese Academy of Sciences
2023
Chromosomes occupy discrete spaces in the interphase cell nucleus, called chromosome territory. The structural and functional relevance of territory remains elusive. We fused 15 17 mouse haploid embryonic stem cells (haESCs), resulting distinct changes territories cognate chromosomes, but with little effect on gene expression, pluripotency gamete functions haESCs. karyotype-engineered haESCs were successfully implemented generating heterozygous (2n = 39) homozygous 38) models. Mice...
10.1038/s41421-022-00511-1
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Cell Discovery
2023-01-24
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