A5094041236- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Properties of Aromatic Compounds
- Catalytic C–H Functionalization Methods
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Biological Evaluation
- Coenzyme Q10 studies and effects
- Photochromic and Fluorescence Chemistry
- Biochemical and biochemical processes
- Phenothiazines and Benzothiazines Synthesis and Activities
- Biochemical Acid Research Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Oxidative Organic Chemistry Reactions
- Radical Photochemical Reactions
N.D. Zelinsky Institute of Organic Chemistry
2023-2024
The intermolecular oxime radical addition to CC bonds was observed and studied for the first time. diacetyliminoxyl proposed as a model reagent study of reactivity towards unsaturated substrates, which is important in light active development synthetic applications radicals. In present work it found that reacts with vinylarenes conjugated dienes give products, whereas unconjugated alkenes can undergo or allylic hydrogen substitution by depending on substrate structure. Remarkably,...
: The synthesis of a series multifunctionalized 4,5-diarylpyridazines via inverse electron-demand Diels-Alder reaction between highly oxygenated diarylacetylenes and unsubstituted 1,2,4,5-tetrazine was developed using polyalkoxybenzenes isolated from industrial essential oils as starting material. proceeded smoothly to afford combretastatin A-4 analogs with pyridazine linker in consistently high yield. In phenotypic sea urchin embryo assay, diarylpyridazine 3,4,5-trimethoxyphenyl 3-amino-4-...
Abstract Based on the parsley seed main component, apiol, efficient approach to polymethoxyquinone C3- and C4-acids was developed. The key step of this is Baeyer–Villiger rearrangement carbonyl-substituted polyalkoxybenzenes derived from extracts. These acids are MeO-analogues natural antioxidants – metabolites ubiquinone idebenone. Due antioxidant properties, they potential therapeutic candidates for treatment mitochondrial dysfunction.