A5091732254- Organic Chemistry Cycloaddition Reactions
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Reactions
- Synthesis of heterocyclic compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Radical Photochemical Reactions
- Synthesis and biological activity
- Organic and Molecular Conductors Research
- Oxidative Organic Chemistry Reactions
- Multicomponent Synthesis of Heterocycles
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Synthesis and Biological Evaluation
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Coenzyme Q10 studies and effects
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Chemical Synthesis and Analysis
- Click Chemistry and Applications
- Membrane Separation and Gas Transport
- Vanadium and Halogenation Chemistry
- Biochemical Acid Research Studies
- Molecular spectroscopy and chirality
- Chemical Reaction Mechanisms
N.D. Zelinsky Institute of Organic Chemistry
2012-2024
Siberian State University of Telecommunications and Informatics
2023
Kyiv National University of Technologies and Design
2019
Russian Academy of Sciences
1986-2016
Sulfonylated N-unsubstituted enamines were synthesized through a chain of chemical and electrochemical transformations via sulfonylation vinyl azides. The disclosing the synthesis was based on unique property azido group, which is its ability to eliminate N2 molecule. Furthermore, formal paradox observed: double bond reacts retained. Electrosynthesis proceeded in an undivided cell equipped with graphite anode stainless steel cathode; NH4I used as supporting electrolyte.
A series of both novel and reported combretastatin analogues, including diarylpyrazoles, -isoxazoles, -1,2,3-triazoles, -pyrroles, were synthesized via improved protocols to evaluate their antimitotic antitubulin activity using in vivo sea urchin embryo assay a panel human cancer cells. systematic comparative structure-activity relationship studies these compounds conducted. Pyrazoles 1i 1p, isoxazole 3a, triazole 7b found be the most potent antimitotics across all tested causing cleavage...
Copper(<sc>i</sc>) halides were used as mediators in the synthesis of β-hydroxysulfones <italic>via</italic> oxysulfonylation styrenes using sulfonylhydrazides.
Solid-state batteries are the next step on way of developing lithium power sources because combination high energy density (up to 500 W/kg and 1000 W/l) better safety. Yet their major drawbacks interfacial resistance poor interface contacts between solid electrolyte active material. One possible solutions problem is produce an material whose particles would be coated with a electrolyte. Titanium-aluminum-lithium phosphate Li1,3Al0.3Ti1.7(PO4)3 (LATP) which exhibits one highest conductivity...
This article presents a novel approach for synthesizing new 5,8-dimethoxy derivative of esculetin via the selective cleavage methylene bridge in sabandin—naturally occurring and easily synthetically accessible methoxylated coumarin. A high selectivity is achieved by using acetoxylation methylenedioxy group with lead tetraacetate. Natural coumarin sabandin as starting compound was prepared few simple steps from 5-allyl-4,7-dimethoxybenzo[d][1,3]dioxole (apiol), which readily available parsley...
Metathesis polytricyclononenes were synthesized via ROMP polymerization in the presence of 1-st generation Grubbs catalyst and their gas-transport properties studied for first time. The aim this work was to evaluate influence Me3E-groups (E = C, Si, Ge) on gas permeation parameters materials. New metathesis poly(3-tert-butyltricyclononene-7) poly(3-trimethylgermyltricyclononene-7) obtained with high yields (up 95%) high-molecular weights (Mw∼3–7×105 g mol−1). glass transition temperatures...
: The synthesis of a series multifunctionalized 4,5-diarylpyridazines via inverse electron-demand Diels-Alder reaction between highly oxygenated diarylacetylenes and unsubstituted 1,2,4,5-tetrazine was developed using polyalkoxybenzenes isolated from industrial essential oils as starting material. proceeded smoothly to afford combretastatin A-4 analogs with pyridazine linker in consistently high yield. In phenotypic sea urchin embryo assay, diarylpyridazine 3,4,5-trimethoxyphenyl 3-amino-4-...
An effective method is developed for the construction of 12-membered thiacrown ethers [8-substituted 1,4-dioxa-7,10-dithiacyclododecanes (5a-c)] which involves homolytic cycloaddition 3,6-dioxaoctane-1,8-dithiol (3) to alkynes 4a-c induced by tripropylborane in presence oxygen.