A5078962748- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Cyclopropane Reaction Mechanisms
- Oxidative Organic Chemistry Reactions
- Radical Photochemical Reactions
- Synthesis and Biological Evaluation
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Electrochemical Analysis and Applications
- Synthesis of Organic Compounds
- Chemical Synthesis and Analysis
- Sulfur-Based Synthesis Techniques
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Reactions
- Catalytic C–H Functionalization Methods
- CO2 Reduction Techniques and Catalysts
- Synthesis and Characterization of Heterocyclic Compounds
- Inorganic and Organometallic Chemistry
- Synthetic Organic Chemistry Methods
- Synthesis of heterocyclic compounds
- Ionic liquids properties and applications
- Crystallography and molecular interactions
- Synthesis and Reactions of Organic Compounds
- Electrocatalysts for Energy Conversion
- Vanadium and Halogenation Chemistry
N.D. Zelinsky Institute of Organic Chemistry
2016-2025
Russian Academy of Sciences
1987-2015
Universidad de Alcalá
1997-2014
Université de Rennes
1992-1993
Centre National de la Recherche Scientifique
1992-1993
The data on the use of mediator oxidation systems activated by electric current (anodic or parallel anodic and cathodic) in organic electrosynthesis are considered generalised. Electrochemical activation these permits successful application catalytic versions easy scaling mediator-promoted processes. Chemical environmental advantages electrochemical processes catalysed demonstrated. Examples inorganic mediators for various classes compounds under conditions electrolysis given.
After the appearance of green chemistry concept, which was introduced in vocabulary early 1990s, its main statements have been continuously developed and modified. Currently, there are 10–12 cornerstones that should form basis for an ideal chemical process. This review analyzes accumulated experience achievements towards design products processes reduce or eliminate use generation hazardous substances. The presents views leading Russian scientists specializing various fields this subject,...
Abstract Electrochemically induced multicomponent transformation of salicylaldehydes and two different CH acids in alcohols an undivided cell the presence sodium bromide as electrolyte results efficient selective formation diversely functionalized, medicinally privileged 2‐amino‐4 H ‐chromene scaffolds 65–86% yields. The developed electrocatalytic system affords distinction between according to their reactivity, offers approach scaffold with a predefined arrangement desired substituents....
We describe an approach towards the synthesis of previously unknown 3-benzoyl-1′,3′,6-trimethyl-2′H,3H,4H-spiro[furo[3,2-c]pyran-2,5′-pyrimidine]-2′,4,4′,6′(1′H,3′H)-tetraone. The presented method is based on cyclization 5-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-phenylethyl)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione. It was shown that reaction proceeds through stage bromination starting compound followed by O-nucleophilic attack. structures obtained were established 1H, 13C...
An electrochemically induced catalytic tandem Knoevenagel-Michael reaction of two equivalents 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one with various aromatic aldehydes in ethanol an undivided cell the presence sodium bromide as electrolyte results formation corresponding 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) 80-96% yields. The application this efficient electrocatalytic method to synthesis biologically prominent represents a facile and convenient approach realization reaction.
Data on methods of electrochemical synthesis cyclopropanes are summarized and described systematically. Direct to afford in both cathodic anodic processes considered. Among indirect such as the employing electrogenerated bases also those involving metal complexes, attention is focused most promising for functionally substituted cyclopropanes, namely, electrocatalytic cascade multicomponent transformations CH acids joint electrolysis activated alkenes or carbonyl compounds presence alkali...
The combined electrolysis of barbituric acids and benzylidenemalononitriles or benzylidenecyanoacetates in methanol an undivided cell the presence sodium bromide results efficient MIRC (Michael-initiated ring-closure) formation corresponding spirocyclopropylbarbiturates 45–93% yield. electrocatalytic reaction proceeds smoothly under neutral mild conditions with bearing both electron-donating electron-withdrawing groups. NMR single X-ray diffraction studies indicate that transformation...
The electrocatalytic transformation of aldehydes and pyrazolin-5-one stereoselectively leads to (<italic>R</italic>*,<italic>R</italic>*)-bis(spiro-2,4-dihydro-3<italic>H</italic>-pyrazol-3-one)cyclopropanes in 65–80% yields.