A5037536745- Ionic liquids properties and applications
- Chemistry and Chemical Engineering
- Glycosylation and Glycoproteins Research
- Electrochemical Analysis and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Genomics and Phylogenetic Studies
- Carbohydrate Chemistry and Synthesis
- Microbial Metabolites in Food Biotechnology
- Chemical and Physical Properties in Aqueous Solutions
- Electrochemical sensors and biosensors
- Genomics and Chromatin Dynamics
- Inorganic and Organometallic Chemistry
- Computational Drug Discovery Methods
- Enzyme Catalysis and Immobilization
- Enzyme Production and Characterization
- Chromosomal and Genetic Variations
- Analytical Chemistry and Chromatography
- Microbial Natural Products and Biosynthesis
- X-ray Diffraction in Crystallography
- Nanoparticles: synthesis and applications
- Chemical Synthesis and Reactions
- Crystallization and Solubility Studies
- Nanomaterials for catalytic reactions
- Neuroscience and Neuropharmacology Research
- Biofuel production and bioconversion
N.D. Zelinsky Institute of Organic Chemistry
2016-2025
University of Helsinki
2023
Russian Academy of Sciences
2010-2018
Russian State University for the Humanities
2018
Universität Hamburg
2005-2014
Hamburg University of Technology
2004-2014
Institute of Molecular Genetics
2009-2012
Organometallic reagents and metal catalysts are used ubiquitously in academia industry. Not surprisingly, the biological activity environmental danger of compounds have become topics outstanding importance. In spite rapid development toxicology during last decades, several common historically established "beliefs" still frequently circulating organometallic community. this Tutorial, we discuss existing opinions concerning (1) possibilities toxicity measurements, (2) high toxicities...
The Carbohydrate Structure Databases (CSDBs, http://csdb.glycoscience.ru) store structural, bibliographic, taxonomic, NMR spectroscopic, and other data on natural carbohydrates their derivatives published in the scientific literature. CSDB project was launched 2005 for bacterial saccharides (as BCSDB). Currently, it includes two parts, Bacterial Plant&Fungal CSDB. In March 2015, these databases were merged to single combined information archaeal glycans (the coverage is close complete), as...
Large clusters of coexpressed tissue-specific genes are abundant on chromosomes diverse species. The coordinately misexpressed in diseases also found similar clusters, suggesting that evolutionarily conserved mechanisms regulate expression large multigenic regions both normal development and its pathological disruptions. Studies individual loci suggest silent coregulated embedded repressed chromatin domains, often localized to the nuclear periphery. To test this model at genome-wide scale,...
After the appearance of green chemistry concept, which was introduced in vocabulary early 1990s, its main statements have been continuously developed and modified. Currently, there are 10–12 cornerstones that should form basis for an ideal chemical process. This review analyzes accumulated experience achievements towards design products processes reduce or eliminate use generation hazardous substances. The presents views leading Russian scientists specializing various fields this subject,...
The influence of the structure cations and anions on biological activity ionic liquids is addressed.
Three different types of drug delivery platforms based on imidazolium ionic liquids (ILs) were synthesized in high preparative yields, namely, the models involving (i) binding and IL; (ii) covalent (iii) dual using both approaches. Seven containing salicylic acid (SA-ILs) cation or/and anion prepared, their cytotoxicity toward human cell lines CaCo-2 (colorectal adenocarcinoma) 3215 LS (normal fibroblasts) was evaluated. Cytotoxicity SA-ILs significantly higher than that conventional...
Abstract In diesem Kurzaufsatz haben wir die Umweltprofile häufig verwendeter Übergangsmetalle basierend auf verfügbaren Daten ihrer biologischen Aktivitäten zusammengestellt. Die Analyse dieser Profile deutet darauf hin, dass das Konzept der giftigen Schwermetalle und harmlosen, ungiftigen leichteren Metalle kritisch überdacht werden sollte. Ein Vergleich toxikologischen legt nahe, Palladium‐, Platin‐ Goldverbindungen, oft als toxisch angesehen werden, in Wirklichkeit harmloser sein...
Detailed study on the mechanisms of cytotoxic action various classes ionic liquids including first illustrative guide for designing ILs with targeted biological activity.
A new family of protic ammonium ionic liquids (ILs) with various inorganic anions was synthesized from bio-derived 5-HMF. Starting cellulose biomass, a complete preservation the C6 unit achieved throughout synthetic sequence (no carbon loss). Evaluation green metrics showed significant advantage developed pathway to access ILs natural renewable source, depending on feasible routes 5-HMF manufacturing. The reduced number steps and availability starting materials were key advantages....
Proteins of the PIWI subfamily Aub and AGO3 associated with germline-specific perinuclear granules (nuage) are involved in silencing retrotransposons other selfish repetitive elements Drosophila genome. proteins their 25- to 30-nt PIWI-interacting RNA (piRNAs) considered as key participants piRNA pathway. Using immunostaining, we found a large, nuage-associated organelle testes, piNG-body (piRNA nuage giant body), which was significantly more massive than an ordinary granule. This body...