- Enzyme Production and Characterization
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
- Enzyme Structure and Function
- Microbial Metabolic Engineering and Bioproduction
- Microbial Metabolites in Food Biotechnology
- Phytase and its Applications
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Amino Acid Enzymes and Metabolism
- Studies on Chitinases and Chitosanases
- Peptidase Inhibition and Analysis
- Bacteriophages and microbial interactions
- Food composition and properties
- Protein Structure and Dynamics
- Polar Research and Ecology
- Algal biology and biofuel production
- Protein Hydrolysis and Bioactive Peptides
- Chromium effects and bioremediation
- Bacterial Genetics and Biotechnology
- Anaerobic Digestion and Biogas Production
- Advanced Proteomics Techniques and Applications
- Bioeconomy and Sustainability Development
- Methane Hydrates and Related Phenomena
- Enzyme function and inhibition
Universität Hamburg
2016-2025
Hamburg University of Technology
2016-2025
Biobase (Germany)
2023-2025
HeidelbergCement (United States)
2006
Deutsche Nationalbibliothek
2006
Novozymes (Denmark)
2004
Novo Nordisk (Denmark)
2000
University of Göttingen
1978-1992
From a hot spring of the Azores islands novel thermophilic bacterium belonging to Thermotogales order was isolated. This strain, which grows optimally at 70(deg)C and pH 6.5, is first known extreme thermophile that able degrade native feathers high temperatures. The enzyme system converts feather meal amino acids peptides. On basis physiological, morphological, 16S rDNA studies new isolate found be member identified as Fervidobacterium pennavorans. strain highly related islandicum...
The euryarchaea Picrophilus torridus and oshimae are able to grow around pH 0 at up 65°C, thus they represent the most thermoacidophilic organisms known. Several features that may contribute survival strategy of P. were deduced from analysis its 1.55-megabase genome. has smallest genome among nonparasitic aerobic microorganisms growing on organic substrates simultaneously highest coding density thermoacidophiles. An exceptionally high ratio secondary over ATP-consuming primary transport...
The increasing awareness of man-made environmental impact our modern highly industrialized societies has led to an demand natural products representing additionally a key element within the transition towards circular bioeconomy. In this sense, macroalgae constitute renewable and abundant resource with high usage potentials in wide range very diverse applications. addition respective useable bioactive compounds varying between species more significantly three taxonomic groups, are...
The cultivation of the hyperthermophile Pyrococcus furiosus, thermoacidophile Sulfolobus shibatae and halophile Marinococcus M52 in dialysis membrane reactors resulted cell yields 2.6 g 1−1, 114 1−1 132 (cell dry weight), respectively. In case P. furiosus neither hydrogen (up to 160 μmol 1−1) nor metabolic products were found be responsible for growth cessation at a temperature 90°C. low yield an agitation speed above 1800 rpm demonstrates sensitivity hydrodynamic stress. oxygen transfer...
One of the most thermostable and thermoactive enzymes ever described has been characterized from a hyperthermophilic archaebacterium Pyrococcus furiosus. The enzyme system this bacterium was capable hydrolyzing starch forming mixture various oligosaccharides. Unlike amylases aerobic bacteria does not require metal ions for activity or stability. is catalytically active over very broad temperature range, namely between 40°C 140°C. half life peculiar during autoclaving at 120°C 2 h.
The stability and reusability of soluble enzymes are major concerns, which limit their industrial applications. Herein, alkaline protease from Bacillus sp. NPST-AK15 was immobilized onto hollow core-mesoporous shell silica (HCMSS) nanospheres. Subsequently, the properties proteases were evaluated. Non-, ethane- amino-functionalized HCMSS nanospheres synthesized characterized. nano-supports by physical covalent immobilization approaches. However, attachment activated HCMSS–NH2 showed highest...
The major global and man-made challenges of our time are the fossil fuel-driven climate change a plastic pollution rapidly emerging plant, human animal infections. To meet necessary changes, dramatic transformation must take place in science society. This will involve very intense forward oriented industrial basic research strongly focusing on (bio)technology bioprocesses developments towards engineering zero-carbon sustainable bioeconomy. Within this transition microorganisms-and especially...