A5060075912- Identity, Memory, and Therapy
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Memory Processes and Influences
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Child Abuse and Trauma
- Cognitive Functions and Memory
- Mental Health Research Topics
- Family and Disability Support Research
- Educational and Psychological Assessments
- Mental Health and Psychiatry
- Resilience and Mental Health
- Digital Mental Health Interventions
- Neurotransmitter Receptor Influence on Behavior
- Schizophrenia research and treatment
- Visual perception and processing mechanisms
- COVID-19 and Mental Health
- Impact of Technology on Adolescents
- Psychedelics and Drug Studies
- Complementary and Alternative Medicine Studies
- Treatment of Major Depression
- Attachment and Relationship Dynamics
- Infant Development and Preterm Care
- Olfactory and Sensory Function Studies
- Family Support in Illness
MRC Cognition and Brain Sciences Unit
2019-2025
University of Cambridge
2019-2025
Medical Research Council
2021-2023
University of Exeter
2013-2017
Abstract Young people with childhood adversity (CA) were at increased risk to experience mental health problems during the COVID-19 pandemic. Pre-pandemic research identified high-quality friendship support as a protective factor that can buffer against emergence of in young CA. This longitudinal study investigated buffering effects on symptoms before and three timepoints pandemic 102 (aged 16–26) low moderate Multilevel analyses revealed continuous increase depression following outbreak....
<sec> <title>BACKGROUND</title> Mental ill health is a leading cause of disability worldwide, but access to evidence-based support remains limited. Digital mental interventions offer timely and low-cost solution. However, improvements in clinical outcomes are reliant on user engagement, which can be low for digital interventions. User characteristics, including demographics personality traits, could used tailor platforms promote longer-term engagement improved outcomes. </sec>...
At least half of all patients with mental health disorders do not respond adequately to psychological therapy. Acutely enhancing particular biological or processes during therapy may improve treatment outcomes. However, previous studies are confined specific augmentation approaches, typically assessed within single diagnostic categories. Our objective was assess what degree acute augmentations reduce psychiatric symptoms and estimate effect sizes types (for example, brain stimulation...
Individuals with depression typically remember their past in a generalised manner, at the cost of retrieving specific event memories. This may impair engagement cognitive behavioural therapy (CBT) tasks that use concrete episodic information to challenge maladaptive beliefs, potentially limiting therapeutic benefit. Study 1 demonstrated an specificity induction increased detail and autobiographical memory people major depression, relative control conditions (N = 88). We therefore examined...
Abstract Aberrations to metacognition—the ability reflect on and evaluate self-performance—are a feature of poor mental health. Theoretical models post-traumatic stress disorder propose that following severe or trauma, maladaptive metacognitive evaluations appraisals the event drive development symptoms. Empirical research is required in order reveal whether disruptions metacognition cause contribute symptom line with theoretical accounts, are simply consequence ongoing psychopathology. In...
Introduction Cognitive behavioural therapies (CBTs) are one of the most effective treatments for major depression. However, ~50% individuals do not adequately respond to intervention and those who remit from a depressive episode, over 50% will experience later relapse. Identification patient-level factors which moderate treatment response may ultimately help identify cognitive barriers that could be targeted improve efficacy. This individual patient data meta-analysis explores such potential...
Low-intensity psychological interventions that target cognitive risk factors for depressive relapse may improve access to prevention programs and thereby reduce subsequent risk. This study provides the first evaluation of an autobiographical memory-based intervention prevention, establish whether memory-training are efficacious acute depression also aid those currently in remission. We provide longest follow-up to-date effects memory training on processes themselves. pre-registered...
This trial introduces a novel transdiagnostic intervention (Shaping Healthy Minds) designed to address the gap in effective interventions for people with complex and comorbid presentations including anxiety, disturbed mood, trauma sequelae. Shaping Minds is modular which synthesises several evidence-based treatment techniques, allowing standardised, yet flexible, delivery. We conducted patient-level two-arm randomised controlled (HARMONIC) that compared psychological treatment-as-usual...
Introduction COVID-19-related social isolation and stress may have significant mental health effects, including post-traumatic stress, anxiety depression. These factors are thought to disproportionately affect populations at risk of psychopathology, such as adolescents with a history childhood adversity (CA). Therefore, examining which buffer the impact in vulnerable is critical. The Resilience After COVID-19 Threat (REACT) study assesses whether emotion regulation capacity, inflammation...
Young people with childhood adversity (CA) were at increased risk to experience mental health problems during the COVID-19 pandemic. Pre-pandemic research identified high-quality friendship support as a potent protective factor that can buffer against emergence of in young CA. Hence, this longitudinal study investigated buffering effects on symptoms before and three timepoints pandemic 102 (aged 16-26) low moderate severity levels Assessments took place remotely pandemic, first UK lockdown,...
Aberrations to metacognition— the ability reflect on and evaluate self-performance— are a feature of poor mental health. Theoretical models suggest that following stressful event, maladaptive metacognitive evaluations appraisals event drive development post-traumatic stress symptoms. Yet it is unclear whether disruptions metacognition causes or contributes symptom development, simply consequence ongoing psychopathology. In two studies, using hierarchical Bayesian modelling combined with...
Abstract Aberrations to metacognition— the ability reflect on and evaluate self-performance— are a feature of poor mental health. Theoretical models suggest that following stressful event, maladaptive metacognitive evaluations appraisals event drive development post-traumatic stress symptoms. Yet it is unclear whether disruptions metacognition causes or contributes symptom development, simply consequence ongoing psychopathology. In two studies, using hierarchical Bayesian modelling combined...
Individuals with depression typically remember their past in a generalised manner, at the cost of retrieving specific event memories. This may impair engagement cognitive behavioural therapy (CBT) tasks that use concrete episodic information to challenge maladaptive beliefs, potentially limiting therapeutic benefit. Study 1 demonstrated an specificity induction increased detail and autobiographical memory people major depression, relative control conditions (N=88). We therefore examined...
Emotion can affect the way in which experiences are stored our memory. The dual representation account proposes that traumatic events may be encoded as fragmented sensory-perceptual details without a broader conceptual organisation. This result involuntary retrieval of perceptual information triggered by environmental cues associated context – phenomenon referred to intrusive memories. Currently, it is unknown whether individuals who experience memories have an underlying vulnerability...
The ability to retrieve specific, single-incident autobiographical memories has been consistently posited as a predictor of recurrent depression. Elucidating the role memory specificity in patient-response depressive treatments may improve treatment efficacy and facilitate use science-driven interventions. We used recent methodological advances individual patient data meta-analysis determine a) whether is improved following mindfulness-based cognitive therapy (MBCT), relative control...