A5025751663- Sirtuins and Resveratrol in Medicine
- Aortic Disease and Treatment Approaches
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Phytochemical compounds biological activities
- Phytase and its Applications
- Aortic aneurysm repair treatments
- Biomedical and Engineering Education
- Pineapple and bromelain studies
- Connective tissue disorders research
- Inflammatory mediators and NSAID effects
- Histone Deacetylase Inhibitors Research
- Garlic and Onion Studies
- Electrospun Nanofibers in Biomedical Applications
- Click Chemistry and Applications
- Cancer, Lipids, and Metabolism
- Nanoplatforms for cancer theranostics
- Cardiac Valve Diseases and Treatments
- Cholesterol and Lipid Metabolism
- Autophagy in Disease and Therapy
Kardio-Med Silesia
2022-2024
Wroclaw University of Environmental and Life Sciences
2024
Medical University of Silesia
2017-2024
Justus-Liebig-Universität Gießen
2024
Universities of Giessen and Marburg Lung Center
2024
University Hospital of Zurich
2022
Foundation of Cardiac Surgery Development
2018-2022
University of Silesia in Katowice
2017
Abstract: AKT, a serine/threonine protein kinase and mammalian target of rapamycin (mTOR) plays critical role in the proliferation resistance to apoptosis that are essential development progression colon cancer. Therefore, AKT/mTOR signaling pathway has been recognized as an attractive for anticancer therapy. Inositol hexaphosphate (InsP6), natural occurring phytochemical, shown have both preventive therapeutic effects against various cancers, however, its exact molecular mechanisms action...
Pterostilbene is a dietary phytochemical that has been found to possess several biological activities, such as antioxidant and anti-inflammatory. Recent studies have shown it exhibits the hallmark characteristics of an anticancer agent. The aim study was investigate activity pterostilbene against HT-29 human colon cancer cells, focusing on its influence cell growth, differentiation, ability this stilbene induce death. To clarify mechanism changes in expression genes proteins are directly...
Melanoma is one of the fastest-growing cancers worldwide. Treatment advanced melanoma very difficult; therefore, there growing interest in identification new therapeutic agents. Pterostilbene a natural stilbene that has been found to have several pharmacological activities. The aim this study was evaluate influence pterostilbene on proliferation and apoptosis human cells. Proliferation pterostilbene-treated amelanotic (C32) melanotic (A2058) cells determined by BRDU assay. Flow cytometric...
Treatment of Limbal Stem Cell Deficiency (LSCD), based on autologous transplantation the patient's stem cells, is one few medical cell therapies approved by European Medicines Agency (EMA). It relies isolating and culturing in vivo Epithelial Cells (LESC) then populating them fibrin substrate, creating a scaffold for corneal epithelial regeneration. Such solution implanted into eye. The culture process specific, its results strongly depend initial seeding density. Achieving control density...
Single-center retrospective cohort study to evaluate the impact of oral anticoagulation (OAC) on long-term outcomes conservatively managed acute type B aortic dissection.Clinical and morphological data eligible patients from a high-volume vascular centre 1 January 2003 through 31 December 2020 were evaluated. Patients excluded for: A or non-A-non-B dissection, isolated abdominal intramural haematoma connective tissue disease. The primary outcome was freedom late events (intervention, rupture...
<title>Abstract</title> Treatment of Limbal Stem Cell Deficiency (LSCD), based on autologous transplantation the patient's stem cells, is one few medical cell therapies approved by European Medicines Agency (EMA). It relies isolating and culturing in vivo Epithelial Cells (LESC) then populating them fibrin substrate, creating a scaffold for corneal epithelial regeneration. Such solution implanted into eye. The culture process specific, its results strongly depend initial seeding density....
Pterostilbene is a naturally occurring compound found primarily in blueberries and grapes.It has been to possess several biological activities such as antioxidative anti-inflammatory.The study evaluated the cytotoxic activity of pterostilbene various human cancer cell lines, i.e., melanoma (A2058, C32), colon carcinoma (HT-29, SW1116), breast adenocarcinoma (MCF-7, SKBR3) ovary (SKOV3).The cells were treated with concentrations ranging from 5 75 µM for 72 h.The cytotoxicity was using...