- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Synthesis and Characterization of Heterocyclic Compounds
- Ion channel regulation and function
- Neonatal and Maternal Infections
- Streptococcal Infections and Treatments
- Cardiac electrophysiology and arrhythmias
- Chemistry and Chemical Engineering
- Gastrointestinal disorders and treatments
- Peripheral Nerve Disorders
- Pediatric health and respiratory diseases
- Sepsis Diagnosis and Treatment
- Microwave-Assisted Synthesis and Applications
- Head and Neck Anomalies
- Orthopedic Surgery and Rehabilitation
- Lung Cancer Treatments and Mutations
- Facial Nerve Paralysis Treatment and Research
- Intestinal and Peritoneal Adhesions
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Marine Toxins and Detection Methods
- Pharmaceutical Practices and Patient Outcomes
- Microbial Natural Products and Biosynthesis
- Biochemical and biochemical processes
- Lung Cancer Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
University of Helsinki
2021-2023
B.J. Medical College
2016
Anna Needs Neuroblastoma Answers
2015
Saurashtra University
2014
Government ENT Hospital
1987
Southampton General Hospital
1987
Background:Relaparotomy has to be performed in case of certain post-operative complications. Incidence relaparotomy differs according hospital setup as well patient characteristics and initial surgery. It also depends on care given following first surgery incidence sepsis. This study was carried out know the indications it, so that future this factors can modified further lowered.Methods: is an observational which 75 cases reported during period May 2008 September 2010 were included. All...
Marine-originated spirocyclic bromotyrosines are considered as promising scaffolds for new anticancer drugs. In a continuation of our research to develop potent and more selective compounds, we synthesized library 32 clavatadine analogs by replacing the agmatine, i.e., 4-(aminobutyl)guanidine, side chain with different substituents. These compounds were tested cytotoxicity against skin cancer using human melanoma cell line (A-375) normal fibroblast (Hs27). The highest A-375 was observed...
Accumulation of time lost because broken appointments in general dental practice can lead to an inefficiently-run and may also reduced financial income. This study assessed the reasons for patients failing attend analysed effect two simple interventions reducing numbers appointments.This audited causes a Glasgow over four-month period and, second period, using new methods patient information number target groups population.The majority treatment were unemployed. Simple changes recall letters...
Background: Small bowel perforation is still a major health problem in the developing world with its attendant high morbidity and mortality. Till date has been treated by conventional laparotomy. Early surgery become accepted mode of treatment this improved survival patients. Reports are now available for feasibility laparoscopic repair perforation. Laparoscopy provides diagnostic as well therapeutic capabilities accuracy reaching 100%. The objective study was to benefit approach small...
A series of novel chalcone 4a , 4b 4c 4d 4e 4f 4g 4h 4i 4j 4k 4l and pyrazoline 5a 5b 5c 5d 5e 5f 5g 5h 5i 5j 5k 5l derivatives have been synthesized as potential antibacterial agents. The by reaction various chalcones with hydrazine hydrate in the presence acetic acid. were prepared condensation key aldehyde 3 appropriate acetophenone using basic condition ethanol a solvent. has reacting 2‐(chloromethyl)‐3‐methyl‐4‐(2,2,2‐trifluoroethoxy)pyridine hydrochloride vanillin. structures new...
Abstract Background Bell’s palsy significantly impacts facial function, aesthetics, and quality of life. Objective To compare the effects Kabat Technique (KT) Mirror Book Therapy (MBT) on clinical electrophysiological parameters in patients with palsy. Methods This randomized controlled trial included 31 divided into two groups: KT ( n = 16) MBT 15). Both groups received their respective interventions (6 days/week for 3 weeks) addition to conventional physiotherapy. Sunnybrook Facial Grading...
A series of an easy and efficient route for the synthesis some new 2-amino-3-cyanopyridine (4a-4i) 2-methoxy-3-cyanopyridine (5a-5i) derivatives were synthesized through reaction various chalcone (3a-3i) with malononitrile in presence ammonium acetate sodium methoxide, respectively. The constitutions all compounds have been established by IR, 1H-NMR, Mass spectral data Elemental analysis. Furthermore, products screened their antimicrobial activity.
T-type calcium (CaV3) channels are involved in cardiac automaticity, development, and excitation-contraction coupling normal myocytes. Their functional role becomes more pronounced the process of pathological hypertrophy heart failure. Currently, no CaV3 channel inhibitors used clinical settings. To identify novel ligands, purpurealidin analogs were electrophysiologically investigated. These compounds alkaloids produced as secondary metabolites by marine sponges, they exhibit a broad range...
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Various isopropylacetoacetanilides were treated with 4-(difluoromethoxy)-3-hydroxy benzaldehyde and thiourea/urea in the presence of acid catalyst to produce 1,4-dihydropyrimidine derivatives (4a-5i 5a-5i) good yields. All synthesized compounds characterized by mass, 1 H-NMR IR spectrum, also evaluated for antibacterial antifungal activity against two Gram +ve Gram-ve bacterial fungi strains. The 4e, 4g 5d found comparatively promising active all fungal
Various isopropylacetoacetanilides were treated with 4-(difluoromethoxy)-3-hydroxy benzaldehyde and thiourea/urea in the presence of acid catalyst to produce 1,4-dihydropyrimidine derivatives (4a-5i 5a-5i) good yields. All synthesized compounds characterized by mass, 1 H-NMR IR spectrum, also evaluated for antibacterial antifungal activity against two Gram +ve Gram-ve bacterial fungi strains. The 4e, 4g 5d found comparatively promising active all fungal
A series of an easy and efficient route for the synthesis some new 2-amino-3-cyanopyridine (4a-4i) 2-methoxy-3-cyanopyridine (5a-5i) derivatives were synthesized through reaction various chalcone (3a-3i) with malononitrile in presence ammonium acetate sodium methoxide, respectively. The constitutions all compounds have been established by IR, 1H-NMR, Mass spectral data Elemental analysis. Furthermore, products screened their antimicrobial activity.