A5050832037- Microfluidic and Capillary Electrophoresis Applications
- Essential Oils and Antimicrobial Activity
- Analytical Chemistry and Chromatography
- Effects and risks of endocrine disrupting chemicals
- Analytical Chemistry and Sensors
- Biosensors and Analytical Detection
- Analytical Methods in Pharmaceuticals
- Cholesterol and Lipid Metabolism
- Ginger and Zingiberaceae research
- Microfluidic and Bio-sensing Technologies
- Chemical Analysis and Environmental Impact
- Microplastics and Plastic Pollution
- Cholinesterase and Neurodegenerative Diseases
- Allergic Rhinitis and Sensitization
- Sinusitis and nasal conditions
- Electrochemical sensors and biosensors
- 3D Printing in Biomedical Research
- Natural Compounds in Disease Treatment
- Phytochemicals and Medicinal Plants
- Analytical chemistry methods development
Mahidol University
2014-2024
Chronic rhinosinusitis (CRS) is long-term inflammation of the sinuses that can be caused by infection due to antibiotic-resistant bacteria. Biofilm developed microbes postulated cause antibiotic treatment failure. Thus, anti-biofilm activities seven Thai herbal essential oils (EOs) against bacteria isolated from CRS patients was investigated. Lemongrass (Cymbopogon citratus L.) EO showed most effective antibiofilm activity Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus...
Background and Objectives: The effects of Ocimum tenuiflorum essential oil (OTEO) against gastric cancer remain unknown merit investigation. Materials Methods: In the present study, anti-cancer activity OTEO was examined in a human cell line (AGS). After treatment, AGS viability determined by an MTT assay, inhibition metastasis migration invasion assays. expression apoptosis-related genes treated cells qRT-PCR. Results: significantly decreased dose-dependent manner (IC50 163.42 µg/mL)...
A fast capillary zone electrophoretic method with photodiode array detection (CZE-PAD) was established and validated for assays of commonly prescribed anti-diabetic drugs [metformin (MET), glibenclamide (GBM) gliclazide (GCZ)] in 13 samples including raw material, single combined tablets. CZE optimization revealed baseline separation the analytes (Rs > 5.39) 8 min, 50 mM borate buffer (pH 9.0), using a an effective length 56.0 cm inner diameter µm, voltage 20 kV, temperature 25°C wavelength...
Zephirus environment is polluted by the toluene from profuse range industries. In spite of positive potential application, results in many mishaps especially health hazards; hence amputation crucial for human welfare as well environmental issues. This review deals with destruction using microbial degradation. The overall aerobic biodegradation into carbon dioxide, water and biomass bacteria, fungi mixed culture has been studied comprehensively. Biodegradation technique a promising...
In-capillary derivatization using fluorescamine as the labeling reagent was proposed to enhance detectability of adamantine drugs (memantine, amantadine and rimantadine) by spectrophotometric detection. Fluorescamine were delivered capillary electrophoresis instrument at a ratio 10:1 zone injection. The reaction occurred following application voltage (20 kV). derivatized products, hydrolyzed- excess separated in 7 min 100 mM borate buffer (pH 10.0) containing 0.1% w/v Brij®-35 20% v/v...
Memantine is an N-methyl-D-aspartate receptor antagonist recommended for treatment of Alzheimer’s disease. Due to the lack chromophores/fluorophores in memantine molecule, this work focuses on a novel procedure memantine-fluorescent derivative formation enabling it be monitored by fluorescence detector. 4-(N-Chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulphonyl 2,1,3-benzoxadiazole (DBD-COCl) was chosen as fluorescent probe since carbonyl chloride DBD-COCl could easily react with...
Brompheniramine, an antihistamine drug, was employed as a novel UV probe for capillary electrophoresis with indirect detection of adamantane drugs (memantine, amantadine, and rimantadine). The possesses high molar absorptivity 24 × 103 L/mol cm at 6 mM, which enables the measurement these nonchromophore analytes without derivatization. simple background electrolyte (10 mM sodium dihydrogen phosphate (pH 5.0) containing 5 brompheniramine β-cyclodextrin) provided separation in short time (7.5...
Background and Objectives: Gastric cancer remains a major unmet clinical problem worldwide. Although conventional medical treatments are available, their curative effects generally unsatisfactory. Consequently, it necessary to search natural products for potential alternatives in treating gastric patients. Ocimum x africanum Lour. is culinary herb that has been used folk medicine various diseases, but little known regarding its anti-cancer activity against cells. In the current study, we...