A5035264532- Biosensors and Analytical Detection
- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Chromatography
- Innovative Microfluidic and Catalytic Techniques Innovation
- Essential Oils and Antimicrobial Activity
- Advanced biosensing and bioanalysis techniques
- Analytical Methods in Pharmaceuticals
- Advanced Chemical Sensor Technologies
- Advancements in Transdermal Drug Delivery
- Spectroscopy and Chemometric Analyses
- Analytical Chemistry and Sensors
- Analytical chemistry methods development
- Microfluidic and Bio-sensing Technologies
- Dermatology and Skin Diseases
- Electrowetting and Microfluidic Technologies
- Phytochemistry and Biological Activities
- Curcumin's Biomedical Applications
- Phytochemicals and Antioxidant Activities
- Polydiacetylene-based materials and applications
- Optical Coherence Tomography Applications
- Epilepsy research and treatment
- Natural product bioactivities and synthesis
- Pharmacological Effects and Assays
- Advanced Measurement and Detection Methods
- Biosimilars and Bioanalytical Methods
Mahidol University
2015-2024
University of Tasmania
2014-2017
Siam University
2013
Dublin City University
2013
Interstitial fluid is a readily accessible source of biomarkers for various diseases, providing less invasive and more convenient option than traditional blood or tissue sampling methods. Microneedle-based point-of-care testing devices have gained significant interest due to their potential direct detection target analytes in ISF, accomplished through minimally penetration the stratum corneum. Thus, microneedle-based can be considered as adhesive tools diagnostic sensing therapeutic drug...
Microneedles (MNs) have shown a great potential for the microsampling of dermal interstitial fluid (ISF) in minimally invasive manner point-of-care testing (POCT). The swelling properties hydrogel-forming microneedles allow passive extraction ISF. Surface response approaches, including Box-Behnken design (BBD), central composite (CCD), and optimal discrete design, were employed optimization hydrogel film by studying effects independent variables (i.e., amount hyaluronic acid, GantrezTM S-97,...
Rapid detection of microorganisms by alternative methods is desirable. Electromigration separation have the capability to separate according their charge and size laser-induced fluorescence (LIF) single‐cell capability. In this work, a new combined scheme was introduced using chip‐based capillary electrophoresis (chip‐ CE ) platform with LIF detection. Three E scherichia coli , S taphylococcus aureus C andida albicans were selected as representatives G ram‐positive bacteria, ram‐negative...
The antifungal drug miconazole nitrate has a low solubility in water, leading to reduced therapeutic efficacy. To address this limitation, miconazole-loaded microemulsions were developed and assessed for topical skin delivery, prepared through spontaneous emulsification with oleic acid water. surfactant phase included mixture of polyoxyethylene sorbitan monooleate (PSM) various cosurfactants (ethanol, 2-(2-ethoxyethoxy) ethanol, or 2-propanol). optimal microemulsion containing PSM ethanol at...
Combination of piperaquine (PQ) (320mg) and dihydroartemisinin (DHA) (40 mg) is an anti-malarial formulation, which recommended by World Health Organization (WHO). Simultaneous analysis PQ DHA can be problematic due to the lack chromophores or fluorophores in molecule. Whereas possesses strong UV absorption it presents 8 times contents formulation. In this study, two spectroscopic methods, Fourier transform infrared (FTIR) Raman spectroscopy, were developed for determination both drugs...
Paper-based devices using smartphone-based detection have been widely used for colorimetric analysis due to their simplicity, ease of operation, and handheld capability.Herein, we demonstrate simple measurement dopamine on paper-based devices, which were fabricated in the 96-well plate shape wax printing technique.The reaction was based 3,3',5,5'-tetramethylbenzidine (TMB)-silver nitrate redox reaction.The oxidized TMB possessed blue color could be observed by naked eyes.In presence...
Charantin is a mixture of β-sitosterol and stigmastadienol glucosides, which effectively lowers high blood glucose. Novel molecularly imprinted polymers coated magnetic nanoparticles (Fe3O4@MIPs) filter paper (paper@MIPs) were synthesized by sol-gel polymerization to selectively extract charantin. glucoside was selected as template for imprinting specific recognition owing its larger molecular surface area than that 5,25-stigmastadienol glucoside. Factorial designs used examine the effects...
Turmeric consumption is continually increasing worldwide. Curcuminoids are major active constituents in turmeric and associated with numerous health benefits. A combination of spectroscopic methods chemometrics shows the suitability for food quality control due to advantages such as speed, versatility, portability, no need sample preparation. Five calibration models quantify curcuminoids were proposed using benchtop portable devices. The most remarkable results showed that Raman NIR present...
In-capillary derivatization using fluorescamine as the labeling reagent was proposed to enhance detectability of adamantine drugs (memantine, amantadine and rimantadine) by spectrophotometric detection. Fluorescamine were delivered capillary electrophoresis instrument at a ratio 10:1 zone injection. The reaction occurred following application voltage (20 kV). derivatized products, hydrolyzed- excess separated in 7 min 100 mM borate buffer (pH 10.0) containing 0.1% w/v Brij®-35 20% v/v...
Exosome quantification is important for estimation of informative messengers (e.g., proteins, lipids, RNA, etc.) involving physiological and pathological effects. This work aimed to develop a simple rapid distance-based paper portable device using exosome-capture vesicles (polydiacetylene conjugated with antiCD81) exosome in cell cultures. novel concept relied on distinct aggregation exosomes leading different solvent migration. Distances the migration were used as signal readouts, which...
Previous literature regarding coronavirus disease 2019 outlined a presence of organ dysfunction including acute respiratory distress syndrome and kidney injury that are linked to mortality. Several patients require extracorporeal therapy. This review aims gather available published resources physicochemical pharmacokinetic properties suggests antiviral drug dosing adaptation for 2019-infected critically ill receiving A search was performed using PubMed, clinical trial registries,...