- Spectroscopy and Chemometric Analyses
- Biosensors and Analytical Detection
- Vitamin K Research Studies
- Phytochemicals and Antioxidant Activities
- Vitamin D Research Studies
- Long-Term Effects of COVID-19
- Ginger and Zingiberaceae research
- Edible Oils Quality and Analysis
- Traditional Chinese Medicine Analysis
- Retinoids in leukemia and cellular processes
- Malaria Research and Control
- Microfluidic and Capillary Electrophoresis Applications
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Computational Drug Discovery Methods
- Advanced biosensing and bioanalysis techniques
- Phytochemistry and Biological Activities
- Folate and B Vitamins Research
- Nuts composition and effects
- Clinical Nutrition and Gastroenterology
- African Botany and Ecology Studies
- Metabolism and Genetic Disorders
- Infant Nutrition and Health
- Innovative Microfluidic and Catalytic Techniques Innovation
- Natural product bioactivities and synthesis
University Hospital Hradec Králové
2023-2025
University of Hradec Králové
2023-2024
Mahidol University
2020-2024
Charles University
2023-2024
Abstract Objectives Concentrations of neopterin, kynurenine and kynurenine/tryptophan ratios predict prognosis the need for oxygen therapy in patients hospitalized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aims present study were to evaluate changes these biomarkers early course infection, association with prior disease (COVID-19) vaccination therapeutic administration Anti-SARS-CoV-2 monoclonal antibodies, investigation other potential including neuropilin,...
Combination of piperaquine (PQ) (320mg) and dihydroartemisinin (DHA) (40 mg) is an anti-malarial formulation, which recommended by World Health Organization (WHO). Simultaneous analysis PQ DHA can be problematic due to the lack chromophores or fluorophores in molecule. Whereas possesses strong UV absorption it presents 8 times contents formulation. In this study, two spectroscopic methods, Fourier transform infrared (FTIR) Raman spectroscopy, were developed for determination both drugs...
Abstract Introduction Process analytical technology (PAT) guidance is implemented in the quality assurance of phytocompounds to achieve Industry 4.0 concept. Near‐infrared (NIR) and Raman spectroscopies are feasible for rapid, reliable quantitative analysis through transparent packaging without removing samples from their original containers. These instruments can serve PAT guidance. Objective This study aimed develop online portable NIR spectroscopic methods quantifying total curcuminoids...
Thunbergia laurifolia is used in traditional Thai medicine to reduce fever and treat mouth ulcers. However, the quantitative analysis of chemical markers has not yet been officially defined.
As a representative of the lipophilic vitamins, vitamin K is one most difficult vitamins to analyze. Even modern approaches using mass spectrometry detection cannot be carried out without multi-step, time-consuming, economically, and ecologically demanding sample treatment. These findings suggest an opportunity develop new trends that could shorten simplify whole procedure, whereby emphasizing processing large number samples with additional focus on more environmentally friendly techniques....
Partial least squares-1 (PLS-1), a chemometrics-assisted attenuated total reflectance infrared (ATR-IR) spectroscopy method, for quantitative analysis of caffeic acid and rosmarinic contents in Rang Chuet (Thunbergia laurifolia Lindl.)leaf samples was developed validated.PLS-1 models were performed by using 69 IR spectra calibration set samples.Leave-one-out cross validation utilized model construction.Prediction efficiency the optimum checked from 24 determination results test which not...