A5091007476- Chronic Obstructive Pulmonary Disease (COPD) Research
- Data Management and Algorithms
- Advanced Database Systems and Queries
- Delphi Technique in Research
- Respiratory Support and Mechanisms
- Semantic Web and Ontologies
- Long-Term Effects of COVID-19
- Recommender Systems and Techniques
- Asthma and respiratory diseases
- Pediatric health and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Web Data Mining and Analysis
- Data Mining Algorithms and Applications
- COVID-19 and Mental Health
- Software System Performance and Reliability
- Spatial Cognition and Navigation
- Hand Gesture Recognition Systems
- Respiratory and Cough-Related Research
- Service-Oriented Architecture and Web Services
- Advanced Text Analysis Techniques
- Lung Cancer Diagnosis and Treatment
- Topic Modeling
- Multi-Criteria Decision Making
- Renal function and acid-base balance
- Advanced Software Engineering Methodologies
Charles University
2009-2025
University Hospital Hradec Králové
2015-2025
University of Hradec Králové
2017-2025
Ocní klinika
2021
Opća bolnica Karlovac
2021
University of Mosul
1962
Abstract Objectives Concentrations of neopterin, kynurenine and kynurenine/tryptophan ratios predict prognosis the need for oxygen therapy in patients hospitalized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aims present study were to evaluate changes these biomarkers early course infection, association with prior disease (COVID-19) vaccination therapeutic administration Anti-SARS-CoV-2 monoclonal antibodies, investigation other potential including neuropilin,...
The role of electrocardiography (ECG) in predicting mortality patients with chronic obstructive pulmonary disease (COPD) has not been sufficiently established. Research question: Is a normal ECG associated better prognosis than an abnormal COPD? parameters were assessed enrolled the Czech Multicenter Database COPD. We ECGs from baseline (August 2013) until December 31, 2019, or death. primary endpoint was 5-year overall survival depending on findings. A total 300 subjects study and 143 died...
This position paper has been drafted by experts from the Czech national board of diseases with bronchial obstruction, Pneumological and Phthisiological Society. The statements recommendations are based on both results randomized controlled trials data cross-sectional prospective real-life studies to ensure they as close possible context daily clinical practice current health care system Republic. Chronic Obstructive Pulmonary Disease (COPD) is a preventable treatable heterogeneous syndrome...
Abstract We stratified post-COVID patients into four newly established clinical groups based on the presence or absence of at least one subjective respiratory symptom and objective sign pulmonary involvement. Nearly half outpatients third hospitalized had signs involvement without accompanying symptoms three months after diagnosis.
Background: Adherence to inhaled medication constitutes a major problem in patients with chronic obstructive pulmonary disease (COPD) globally. However, large studies evaluating adherence its entirety and capturing variety of potentially associated factors are still lacking. Objective: To study both elementary types COPD "real-life" assess relationships wide-ranging spectrum clinical parameters. Methods: Data from the Czech Multicentre Research Database (CMRD) COPD, an observational...
<b>Introduction:</b> Physical activity is the 4<sup>th</sup> leading risk factor for global mortality. Healthy people who have less than 5000 steps per day are very inactive. However, there not enough information which amount of can adversely affect mortality in patients with chronic obstructive disease (COPD). This study aimed to evaluate functional status, level daily physical (DPA) COPD and assess association between DPA following 3 years. <b>Methods:</b> was evaluated 174...
There are two important shifts in software development: from object-oriented monoliths to service orientation and the rigid specification-development-delivery agile development when needs of users better taken into account as it can be reacted on changes even during development. In point intersection these movements is use confederations. The concept confederation uses decomposition problem application smaller parts (services) at same time expected very tight cooperation with usual Software...
A considerable number of patients with COVID-19 suffer from respiratory problems in the post-acute phase disease (the second-third month after onset). Individual telerehabilitation and telecoaching are viable, effective options for treating these patients. To treat individually, medical staff must have detailed knowledge their physical activity condition. sensor network that utilizes medical-grade devices can be created to collect data, but price availability might limit such a network's...
Our customer preference model is based on aggregation of partly linear relaxations value filters often used in e-commerce applications. Relaxation motivated by the Analytic Hierarchy Processing method and combining fuzzy information web accessible databases. In low dimensions our well suited also for data visualization. The process translating models (user behavior) to programs (learned recommendation) formalized Challenge-Response Framework ChRF. ChRF resembles remote call reduction...
It is sometimes necessary to operate on data having different sets of attributes. can be caused by the fact that come from sources or we collected amount information about real-world entities. In such cases a unification stored into tables causes either loss too frequent changes in table/database layout. Therefore propose model allowing effective handling data. The model, originally developed for storage and processing non-graphic temporal GIS, ensures all procedures/functions/methods are...
<b>Aim:</b> To assess the nutrition and muscle mass loss in patients with severe COPD its phenotypes. <b>Methods:</b> We analysed baseline data of from Czech Multicenter Research Database. assessed BMI (Body Mass Index), FFMI (Fat Free Index) measured by Skinfold Anthropometry MAMC (Mid-arm circumference) non-dominant upper arm. <b>Results:</b> A total 337 were included analysis, 248 men, mean age 66.7 years, FEV1 44.9%, average CAT 16.8. There 10.1% cachexia, 5.1% underweight, 31.2 % obese....
In this paper, we present an algorithm for evaluating the similarity of pairs signs used in sign language. The proposed is based on visual and compares sequences static positions signing person. does not rely any particular way obtaining necessary geometric form signs. usability has already been tested its pilot implementation a dictionary between Czech Sign Language. Geometric data available 3D animated model was to enhance with possibility searching according partial information obtained...
<b>Introduction:</b> The importance of COPD phenotyping is currently discussed across respiratory expert panels. Czech national guidelines recognize 6 different phenotypes represented by bronchitic, emphysematous, COPD/asthma overlap, cachexia, frequent exacerbator and COPD/bronchiectasis. multicenter research database (CMRD) a prospective project focused on long-term mortality disease evolution in real-life patient cohort. <b>Aims:</b> Our aim was to assess differences all-cause the CMRD...
<b>Background:</b> Czech National COPD Guideline defines six phenotypes and recommends phenotype-specific therapy for each phenotype. <b>Aim:</b> The evaluation of effect based on clinical exacerbations during 24 months follow-up. <b>Methods:</b> Multicentre Research Database is a multicenter observational real-life prospective study patients with post bronchodilator FEV<sub>1</sub>≤60%, enrolled 784 treated according to the Guideline. Cohorts distinct phenotype using were observed compared...
<b>Introduction:</b> During the last decade, GOLD classification of COPD underwent notable evolution. There is limited evidence how latest approach affected distribution patients accross A-D groups. Our aim was to assess predictive value 3 systems (I-IV (pre 2011), (2011-2016) and (2017-present)) in relation long-term mortality from CMRD cohort. <b>Methods:</b> We used prospective data 784 cohort (at 4-year follow-up). Kaplan-Meier survival analysis performed for above mentioned systems....