A5018660174- Reproductive tract infections research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Urinary Tract Infections Management
- Cytomegalovirus and herpesvirus research
- Polyomavirus and related diseases
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- Viral Infections and Vectors
- Education, Psychology, and Social Research
- Bladder and Urothelial Cancer Treatments
- Long-Term Effects of COVID-19
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Nephrotoxicity and Medicinal Plants
- COVID-19 and healthcare impacts
- Herpesvirus Infections and Treatments
- Immune Cell Function and Interaction
- Actinomycetales infections and treatment
- Animal Virus Infections Studies
- Bartonella species infections research
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Medicine, History, and Philosophy
- Bacillus and Francisella bacterial research
University of Hradec Králové
2022-2024
Charles University
2015-2024
University Hospital Hradec Králové
2015-2024
University of Defence
2013
Krajská Zdravotní
2008-2012
Abstract We stratified post-COVID patients into four newly established clinical groups based on the presence or absence of at least one subjective respiratory symptom and objective sign pulmonary involvement. Nearly half outpatients third hospitalized had signs involvement without accompanying symptoms three months after diagnosis.
Abstract Diagnosis of SARS-CoV-2 virus is mainly based on direct detection. Determination specific antibodies has been used mostly for epidemiological reasons. However, select immunoassays showed good correlation to plaque reduction neutralization test (PRNT) in smaller patient cohorts, which suggests their potential as predictors titer. A total 3,699 samples from Covid-19 patients were included the multicentric study performed Czech Republic. Anti-SARS-CoV-2 antibody levels evaluated by 8...
Against a background of rapid increase β-lactamase-producing or multi-resistant pathogenic bacteria and the resulting lack effective antibiotic treatment, some older antibiotics have been tested for new therapeutic uses. One these is fosfomycin, to which according studies resistant are very sensitive. Our study was designed because there no data on fosfomycin susceptibility rate in Czech Republic. In this from January 2013 June 2014 3295 unique isolates Gram-negative had caused urinary tract...
Background/Aim. Obesity is currently considered to be the most frequent metabolic disease worldwide, not only in developed but also developing countries. The aim of this work was describe development health status soldiers Armed Forces Czech Republic (ACR) and emphasize markers non-communicable diseases. Our study describes anthropometric biochemical parameters a large group Army professional soldiers. Data were obtained over period 11 years. Methods. During monitored period, from 1999 2009,...
Fosfomycin represents a relatively old antibiotic, but it is experiencing comeback in recent years. According to some studies, the increasing therapeutic use of this drug led rapid increase levels resistance bacteria causing urinary tract infection. In presented study, fosfomycin more than 3500 bacterial isolates before and after introduction into Czech Republic clinical efficacy treatment 300 patients using were assessed. The results show that Escherichia coli registration not significantly...
Abstract We report the case of isolation Bordetella trematum from respiratory tract a patient with lung carcinoma. This gram-negative, opportunistic rod was firstly described in 1996. To date, only several strains have been isolated and reported, mostly skin soft tissue infections. The admitted to ICU Pulmonary Department incipient septic shock failure. Intravenous fluid resuscitation non-invasive ventilation were administered immediately. A broad spectrum antibiotic piperacillin/tazobactam...
Although Francisella (F.) tularensis is a well-described and understood zoonotic pathogen, its importance in Central Europe relatively minor and, as such, tularaemia may be missed the differential diagnosis. The annual incidence of Czech Republic stable with up to 100 reported cases per year, except epidemic years 1998 1999 225 222 cases, respectively. It is, however, higher comparison neighbouring countries. common route transmission handling infected animals. Tularaemia not commonly...
Aside from the general population, COVID-19 pandemic has also affected a group of patients in palliative oncology care. In this study, long-term immune responses against SARS-CoV-2 after vaccination were monitored cohort This non-randomized, prospective, and open-label pilot study recruited Palliative Oncology Program included 147 patients, which 80 females (54.4%) 67 males (45.6%). The overall evaluation current health status, anti-S IgG titer, neutralizing antibodies using virus...
Cíl studie: Cílem studie bylo vyhodnotit klinický výsledek pacientů hospitalizovaných pro onemocnění covid-19 ve dvou univerzitních nemocnicích v letech 2021–2022, definovat rizikové faktory a vliv specifické léčby. Typ multicentrická retrospektivní. pracoviště: anesteziologicko‑resuscitační pracoviště. Materiál metoda: Do byli zařazeni dospělí pacienti hospitalizovaní covid-19, u kterých byly sledovány demografické údaje, komorbidity, vakcinace, podpora ventilace specifická farmakoterapie....
The incidence of mumps has decreased in many countries since the introduction vaccination programmes, however, past decade a rapid increase disease occurrence been reported worldwide. reason for this situation is still not clear. We present results serological survey carried out Eastern Bohemia Region Czech Republic during years 2008-2012.In total, 2,536 samples 2,034 patients were examined study period. cohort was divided into two groups, one consisted individuals born before mandatory and...
Human polyomaviruses such as JC polyomavirus and BK have long been well known pathogens of immunocompromised patients. Several new members this viral family described during the last decade. 9 seems to be a novel pathogen transplanted patients according some studies. The aim our study was determine presence human in after kidney or stem cell transplantation (SCT) at University Hospital Hradec Kralove, Czech Republic. Overall 100 patients, 65 35 SCT, were included into study. At least three...
Fakultní nemocnice a
Rapid antigen tests for the detection of SARS-CoV-2 are commonly used diagnosis Covid-19. Previously published data showed a wide range sensitivity and specificity RATs, but these studies were performed on relatively small numbers samples using only limited virus variants. The aim study was to evaluate main parameters RAT 4 different variants in comparison with PCR.