- Reconstructive Surgery and Microvascular Techniques
- Wound Healing and Treatments
- Nerve Injury and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Nerve injury and regeneration
- Sarcoma Diagnosis and Treatment
- Pain Management and Treatment
- Surgical site infection prevention
- Stroke Rehabilitation and Recovery
- Bone fractures and treatments
- Burn Injury Management and Outcomes
- Cardiac Ischemia and Reperfusion
- Tendon Structure and Treatment
- Musculoskeletal pain and rehabilitation
- Anesthesia and Neurotoxicity Research
- Pain Mechanisms and Treatments
- Trauma Management and Diagnosis
- Elbow and Forearm Trauma Treatment
- Pleural and Pulmonary Diseases
- Pressure Ulcer Prevention and Management
- Vascular Tumors and Angiosarcomas
- Virtual Reality Applications and Impacts
- Body Contouring and Surgery
- Bone Tumor Diagnosis and Treatments
BG Klinik Tübingen
2018-2025
University of Tübingen
2018-2025
Unfallkrankenhaus Berlin
2025
Charité - Universitätsmedizin Berlin
2025
Universitätsklinikum Tübingen
2023
University Children's Hospital Tübingen
2021
Martin-Luther-Krankenhaus
2016-2018
BG University Hospital Bergmannsheil Bochum
2013-2017
Ruhr University Bochum
2012-2017
Klinikum Ludwigshafen
2013-2015
Abstract Background Foot drop is a challenging condition that significantly impacts the affected patient's mobility and quality of life. Tendon transfer has emerged as viable treatment option. We hereby present data tendon procedures in patients with foot our department. Besides detailed description surgical technique, we also compare results those reported literature. Methods Data from 17 (11 males 6 females) suffering due to peripheral nerve or muscle lesions were retrospectively analyzed....
Abstract Background Phantom limb pain (PLP) is a restrictive condition in which patients perceive that no longer present, greatly reducing their quality of life. Mirror Therapy, wherein observe mirror reflection intact limb, has demonstrated efficacy alleviating PLP. However, its unilateral and seated nature presents limitations. To address these constraints while still PLP, evaluating the impact different virtual representations (anthropomorphic vs. non-anthropomorphic) on user’s sense...
Artificial intelligence (AI) continues to advance in healthcare, offering innovative approaches enhance clinical decision-making and patient management. Peripheral nerve surgery poses unique challenges due the complexity of cases need for precise diagnostic therapeutic strategies. This study investigates application OpenAI's generative AI model, o1, assisting with intricate processes peripheral surgery. Utilizing advanced prompt engineering techniques, o1 was configured as a virtual medical...
Chronic wounds of the lower extremity are difficult to treat, especially in patients with peripheral arterial disease (PAD). This patient population frequently suffers from multiple comorbidities, which further impairs wound healing. Local flaps often not available, or insufficient cover these defects, and limbs amputated, although they could possibly be salvaged by free tissue transplantation. Although there is a growing evidence that transfer may feasible otherwise doomed extremities,...
Computerized gait analysis is a common evaluation method in rat models of hind limb nerve injuries, but its use remains unpublished segmental injury the forelimb. It was aim this work to investigate if computerized feasible model median and autograft repair. Ten male Lewis rats underwent 7-mm resection right with immediate The left resected without repair served as an internal control. Animals were assessed for 12 weeks after surgery via CatWalk (CW) every 2 weeks. Evaluation motor recovery...
Thrombotic occlusion of the microvascular pedicle is major reason for flap loss. Thus, identifying patients who are at risk such events paramount. Rotational thromboelastometry (RTE) widely used to detect coagulopathy and hypercoagulable states. The aim our study was assess its diagnostic value in reconstructive microsurgery. In all 181 undergoing free tissue transfer department between February 2010 November 2011 preoperative RTE performed. addition, coagulation values as well patient's...
Surgical flaps have become safe and reliable reconstructive tools, but total flap loss rates as high 25 percent partial 36 been reported due to insufficient perfusion. Therefore, a reliable, noninvasive, effective way improve the microcirculation of surgical is desirable. The aim this study was assess effect remote ischemic conditioning on pedicled free flaps.Thirty patients undergoing (n = 20) 10) tissue transfer were included in study. Remote applied upper extremity for three cycles...
The human hand is the body part most frequently injured in occupational accidents, accounting for one out of five emergency cases and often requiring surgery with subsequently long periods rehabilitation. This paper proposes a Virtual Reality game to improve conventional physiotherapy rehabilitation, focusing on resolving recurring limitations reported technological solutions problem, namely limited diversity support movements exercises, complicated calibrations exclusion patients open...
Four patients underwent targeted sensory reinnervation (TSR), a surgical technique in which defined skin area is first selectively denervated and then surgically reinnervated by another nerve. In our case, either the of lateral femoral cutaneous nerve or saphenous was sural Patients were fitted with special prosthetic device capable transferring sense pressure from sole prosthesis to newly wired area. Pain reduction after TSR highly significant all patients. three patients, permanent pain...
Remote ischemic conditioning (RIC) is known to improve microcirculation in various settings, but little about the impact of amount tissue mass or limb itself. Since ischemia and subsequent necrosis flaps one most dreaded complications reconstructive surgery, adjuvant methods are desirable. We therefore performed a randomized trial compare effect arm versus leg for RIC cutaneous antero–lateral thigh. Forty healthy volunteers were undergo 5 min either upper lower extremity, followed by 10...
Surgical flaps have become reliable tools in the microsurgical armamentarium, but are still faced with tissue loss due to impaired perfusion which can lead complete flap failure. Remote Ischemic Conditioning (RIC) has been demonstrated be an effective way improve microcirculation surgical humans. However, little is known about optimal amount and length of RIC cycles.Determination a superior protocol for cutaneous humans.60 healthy volunteers were randomized into different groups received...
The purpose of this study was to compare donor-site morbidity after anterolateral thigh (ALT) and parascapular (PS) free flap harvest in the same patient. A total 13 patients were included study. Because initial loss, each patient received ALT as well PS transplantation. 10 available for follow-up. average follow-up time 44.5 months. Besides physical examination, range motion scar dimensions assessed objectify deficiencies. subjective by using a self-report questionnaire. In addition,...
Lower extremity reconstruction utilizing free tissue transfer has become a common and safe procedure. Postoperative care especially timing duration of dangling however have not yet been extensively studied. We therefore aimed to assess the changes in oxygenation hemoglobin concentration lower flaps during dangling. A total 19 patients who underwent microsurgical leg (nine parascapular, five latissimus dorsi, anterolateral thigh [ALT] flaps) were included prospective study. Beginning on 6th...
Background Restoring hand and finger function after a traumatic injury necessitates regimen of consistent conscientious exercise. However, motivation frequently wanes due to unchallenging repetitive tasks or discomfort, causing exercises be performed carelessly avoided completely. Introducing gamification these can make them more appealing patients, ultimately increasing their exercise consistently. Objective This study aims iteratively develop serious virtual reality game for rehabilitation...
In the light of persisting lack donor organs and risks allotransplantations, possibility liver regeneration with autologous stem cells from adipose tissue (ADSC) is an intriguing alternative. Using a model toxic damage in Sprague Dawley rats, generated by repetitive intraperitoneal application retrorsine allyl alcohol, ability human ADSC to support restoration function was investigated. A two-thirds hepatectomy performed, were injected into one remaining lobe group 1 (n = 20). Injection cell...
Data on prognostic factors and treatment outcomes for chest wall soft tissue sarcomas (STS) are sparse. Wide resections with negative margins the mainstay of therapy, but impact surgical remains controversial. The purpose present study was to determine significance microscopic through a long-term follow-up. associations between local recurrence-free survival (LRFS), overall (OS) potential were retrospectively assessed in consecutive series 110 patients who suitable curative intent. Potential...
Background The omental flap is a reliable for the coverage of sternal defects. However, little known about predictors mortality and long-term outcome in such patients. Methods We, therefore, performed retrospective study from 2002 to 2013, including all patients who underwent reconstruction with flap. Results A total 50 were identified mean follow-up was 3.8 years. Patient data collected charts 14 available telephone interviews. majority suffered deep wound infections. There no complete loss...
Chronic wounds are a serious problem in clinical work and heavy burden for individuals society. In order to develop novel therapies, adequate model systems the investigation of wound healing required. Although past years different vitro models have been established, true human-like does still not exist. Animal limited their use due species-specific differences skin, lengthy manufacturing process, experimental costs, ethical concerns. Both 2D 3D usually comprised only one or two skin cell...