A5001245517- Ion-surface interactions and analysis
- X-ray Spectroscopy and Fluorescence Analysis
- Nuclear Physics and Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Radiation Therapy and Dosimetry
- Electron and X-Ray Spectroscopy Techniques
- Radiation Detection and Scintillator Technologies
- Radioactive element chemistry and processing
- Diamond and Carbon-based Materials Research
- Advancements in Photolithography Techniques
- Nanofabrication and Lithography Techniques
- Silicon Carbide Semiconductor Technologies
- Polymer Nanocomposite Synthesis and Irradiation
- Advanced Surface Polishing Techniques
- Metal and Thin Film Mechanics
- Photonic and Optical Devices
- Advanced Radiotherapy Techniques
- Luminescence Properties of Advanced Materials
- Advanced X-ray and CT Imaging
- Radioactivity and Radon Measurements
- Air Quality and Health Impacts
- Particle accelerators and beam dynamics
- Thin-Film Transistor Technologies
- Trace Elements in Health
- Advancements in Battery Materials
National Institutes for Quantum Science and Technology
2015-2025
Takasaki Advanced Radiation Research Institute
2007-2023
Advanced Science Research Center
2010-2023
Central Research Institute of Electric Power Industry
2021
Gwangju Institute of Science and Technology
2021
Saitama University
2021
National Institute of Advanced Industrial Science and Technology
2021
Japan Atomic Energy Agency
2007-2016
Kaken Pharmaceutical (Japan)
2016
Koken (Japan)
2016
In addition to being initially developed as an energy driver for inertial confinement fusion, intense, pulsed, light-ion beam (LIB) has been found be applied materials science. If a LIB is used irradiate targets, high-density ‘‘ablation’’ plasma produced near the surface since range of in very short. Since first demonstration quick preparation thin films ZnS by ion-beam evaporation (IBE) using LIB-produced ablation plasma, various have successfully prepared, such ZnS:Mn, YBaCuO, BaTiO3,...
To confirm the quantitative accuracy of PIXE analysis instruments, we measured NIST SRM air particles on filter media using different types instrument: in-air micro-PIXE, PIXE, in-vacuum and micro-PIXE. Then, compared values with certified reference SRM. We found that each instrument were within 90% to 110% NIST-certified for most elements. In particular, major elements ranged from (Kyoto University), micro-PIXE at Tohoku University, relative errors are also small. These results will aid in...
We describe a new method for estimating the beam range in heavy-ion radiation therapy by measuring ion bremsstrahlung. experimentally confirm that secondary electron bremsstrahlung process provides dominant contribution. A Monte Carlo simulation shows number of background photons from annihilation gamma rays is about 1% strength low-energy region used our estimation (63-68 keV). Agreement between experimental results and theoretical prediction characteristic shape spectrum validates...
The ion beam facility at the Takasaki Advanced Radiation Research Institute, National Institutes for Quantum and Radiological Science Technology, consists of a cyclotron three electrostatic accelerators, they are dedicated to studies materials science bio-technology. paper reviews this unique accelerator complex in detail from viewpoint its configuration, specification, typical accelerator, or irradiation technologies applications. institute has also facilities electron beams 60Co gamma-rays...
We investigated the spatial distributions of alkaline earth elements (Mg, Ca, Sr and Ba) in tea leaves using micro-particle-induced X-ray emission (micro-PIXE) analysis to determine elements’ concentrations translocations. examined samples [Camellia sinensis (L.) Kuntze] that had taken up Ba via foliar absorption, while Mg Ca been absorbed through roots as usual. observed accumulation was similarly localized distributed throughout leaves, suggesting variation properties plants.
Antiviral treatment is recommended for chronic hepatitis C patients with advanced fibrosis to reduce and prevent cirrhosis-related complications.To evaluate the efficacy safety of telaprevir (TVR)-based triple therapy in a clinical practice setting.This prospective, multicentre study consisted 102 (METAVIR score F3-4) who were infected HCV genotype 1b. All received 12 weeks TVR combination 24 pegylated interferon (PEG-IFN) α2b ribavirin (RBV).The sustained virological response (SVR) rate was...
Purpose To develop a silicon (Si) and cadmium telluride (CdTe) imaging Compton camera for biomedical application on the basis of technologies used astrophysical observation to test its capacity perform three-dimensional (3D) imaging. Materials Methods All animal experiments were performed according Animal Care Experimentation Committee (Gunma University, Maebashi, Japan). Flourine 18 fluorodeoxyglucose (FDG), iodine 131 (131I) methylnorcholestenol, gallium 67 (67Ga) citrate, separately...
To prevent and control disease caused by exposure to various agents, it is necessary determine the harmful level of intervention establish a method for measuring that level. In-air microparticle-induced X-ray emission (in-air micro-PIXE) analysis based on irradiation specimens with proton ion microbeam, has been modified biological application. Two-dimensional quantitative using system confirmed asbestos induced apoptosis upregulating Fas expression also revealed accumulation...
The cellular mechanisms involved in the development of silicosis have not been fully elucidated. This study aimed to examine influence silica-induced lung injury on autophagy. Suspensions crystalline silica particles were administered transnasally C57BL/6j mice. Immunohistochemical examination for Fas and p62 protein expression was performed using tissue specimens. Two-dimensional quantitative analysis deposits lungs situ sections by an in-air microparticle induced X-ray emission (in-air...
Inhalation of asbestos increases the risk lung cancer and pulmonary fibrosis. It is difficult to directly assess distribution content inhaled particles in tissue sections. The purpose this study employ an in-air micro particle induced X-ray emission (in-air micro-PIXE) system for assessment spatial other metals tissue. A proton ion-microbeam from was applied irradiate patients with or without asbestosis, tumor both groups, fibers (in vitro). each element composing those were calculated their...
FeRh thin films were irradiated with a focused 10 MeV I 2 ×2 µm ion microbeam at intervals of several µm. Following irradiation, the magnetic state surface was observed via force microscopy. The micrometer-sized regions show ferromagnetic while unirradiated remain in an anti-ferromagnetic state. Results indicate that energetic can be used as tool to produce modulations lateral states films.
Pulmonary alveolar proteinosis (PAP) is a rare disease occurred by idiopathic (autoimmune) or secondary to particle inhalation. The in-air microparticle induced X-ray emission (in-air micro-PIXE) system performs elemental analysis of materials irradiation with proton microbeam, and allows visualization the spatial distribution quantitation various elements very low background noise. aim this study was assess PAP due inhalation harmful particles employing micro-PIXE for intracellular iron in...