A5006181823- Nanoparticle-Based Drug Delivery
- Advanced Drug Delivery Systems
- Fatty Acid Research and Health
- Advanced Glycation End Products research
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Drug Solubulity and Delivery Systems
- Nephrotoxicity and Medicinal Plants
- Peptidase Inhibition and Analysis
- Saffron Plant Research Studies
- Phytochemistry and Bioactivity Studies
- Supramolecular Self-Assembly in Materials
- Photodynamic Therapy Research Studies
- Angiogenesis and VEGF in Cancer
- Free Radicals and Antioxidants
- Phytochemistry and Biological Activities
- Corneal Surgery and Treatments
- Plant-based Medicinal Research
- Microbial Inactivation Methods
- Nanomaterials for catalytic reactions
- Immune Response and Inflammation
- Oral and gingival health research
- Histone Deacetylase Inhibitors Research
- Retinal Development and Disorders
Devi Ahilya Vishwavidyalaya
2019-2024
Institute for Postgraduate Medical Education
2023
Central Leather Research Institute
2018
University of Maryland, Baltimore
2005-2007
New York Medical College
2004-2005
The surface of the eye actively suppresses inflammation while maintaining a remarkable capacity for epithelial wound repair. Our understanding mechanisms that balance inflammatory/reparative responses to provide effective host defense preserving tissue function is limited, in particular, cornea. Lipoxin A4 (LXA4) and docosahexaenoic acid-derived neuroprotectin D1 (NPD1) are lipid autacoids formed by 12/15-lipoxygenase (LOX) pathways exhibit anti-inflammatory neuroprotective properties. Here,...
We have developed a procedure for the synthesis of N-hydroxy-N1-phenyloctanediamide (suberoylanilide hydroxamic acid (SAHA)), providing product in 79.8% yield. SAHA is potent inhibitor histone deacetylase, induces differentiation and/or apoptosis certain transformed cells culture, and suppressed growth human prostate cancer LNCaP PC-3 cell lines. The combination with other compounds inhibited proliferation additive fashion resulted synergistic inhibition.
Purpose Bioprinting is a promising technology, which has gained recent attention, for application in all aspects of human life and specific advantages different areas medicines, especially ophthalmology. The three-dimensional (3D) printing tools have been widely used applications, from surgical planning procedures to 3D models certain highly delicate organs (such as: eye heart). purpose this paper review the dedicated research efforts that so far made highlight applications field...
Aim: The present investigation aimed to develop a chemo-free, nanophytosomal system treat triple-negative breast cancer (TNBC) via phyto–photo dual treatment strategy. Method: Size, shape, surface analysis, photoprovoked release profile, photothermal stability, (3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide assay, apoptotic DNA fragmentation, in vitro cellular uptake evaluation, mitochondrial membrane potential and caspase-3 photodynamic evaluation. Results: Biological...
1. IntroductionBreast cancer with triple-negative status (TNBC), which affects two out of every 12000 women, is the most challenging form disease (Bianchini et al., 2022;Zagami and Carey, 2022).Various factors contribute to difficulty in treating TNBC, such as absence early diagnostic tools, presence negative hormonal expressions, rapid progression disease, lack a specific treatment (Fan He, 2022;Luo 2022;Mehraj 2022).For oncologists rely on chemotherapy, radiotherapy, therapy; however,...
Hepatic glycogen is the main buffer for blood glucose levels. Following a meal, hepatocytes take up from portal vein and store it as glycogen, branched polymer of residues. content varies 2 fold during day can constitute to 10% weight liver in humans. During periods fasting increased energy demands, hepatic be broken down into glucose, which released circulation maintain levels.Histomorphometry digital image analysis approach that relies on identification morphological elements histological...