To evaluate the 6-month efficacy and safety of 650 nm low-level red light (LLRL) for myopia control in children.This was a single-center, single-masked randomized controlled trial. A total 224 children aged 6-12 years with spherical equivalent error (SER) - 6 diopter (D) to 0.5 D were enrolled, LLRL group or group. Children underwent treatment twice daily, each lasting 3 min, there an interval at least 4 h between treatments. both groups allowed wear single-vision spectacles; no additional...

Abstract Soil salinity impairs plant growth reducing crop productivity. Toxic accumulation of sodium ions is counteracted by the Salt Overly Sensitive (SOS) pathway for Na + extrusion, comprising transporter SOS1, kinase SOS2, and SOS3 as one several Calcineurin‐B‐like (CBL) Ca 2 sensors. Here, we report that receptor‐like GSO1/SGN3 activates independently binding, physical interaction phosphorylation at Thr16. Loss GSO1 function renders plants salt sensitive both sufficient required...

Abstract Protein ubiquitination is a reversible process catalyzed by ubiquitin ligases and ubiquitin-specific proteases (UBPs). We report the identification characterization of UBP16 in Arabidopsis thaliana. functional protease its enzyme activity required for salt tolerance. Plants lacking were hypersensitive to stress accumulated more sodium less potassium. positively regulated plasma membrane Na+/H+ antiport activity. Through yeast two-hybrid screening, we identified putative target...

ABSTRACT Aiming at the problem of rough and porous surfaces mechanical properties thermoplastic polyurethane elastomer (TPU) parts prepared by selective laser sintering, this article used dip‐dyeing process to improve surface modification TPU parts. It researched solvent type, temperature, time, pH value dyeing solution, initial concentration dyes on performance, properties, analyzed mechanism immersed in simultaneous dyeing. After dip‐dyeing, formed a homogeneous integument; roughness was...

When designing an inspection robot for cage-reared broiler chickens, it is imperative to meticulously contemplate both the performance of within designated workspace and its energy efficiency. The paper optimizes structure consumption by analyzing working environment power usage associated with lifting lowering functions. Inspection robots designed chickens are required operate densely populated chicken coops, underscoring critical importance maneuverability these machines. This research...

Possible association between Helicobacter pylori infection (HPI) and nonalcoholic fatty liver disease (NAFLD) has been proposed by several studies with inconsistent conclusions. Here, we studied the HPI NAFLD at 3 levels: (i) genetic level; (ii) small molecular (iii) clinical level. Relation data diseases, genes, molecules were acquired from Pathway Studio ResNet Mammalian database. Clinical 2263 elderly South Chinese subjects, including 603 patients 1660 subjects without NAFLD. Results...

In order to build an intelligent management platform for remote monitoring of livestock and poultry breeding environment based on the Internet Things big data, behavioral physiology production performance tracking monitoring, this article uses broilers as example independently develop automatic detection system sick chickens ResNet residual network. network can alleviate problem disappearance gradient descent difficulty optimization number layers increases. This is traditional By improving...

Abstract Previous clinical studies highlighted nonalcoholic fatty liver disease (NAFLD) as a hepatic facet of metabolic syndrome, which progresses toward Type 2 diabetes along with an elevation HbA1c in the blood. Longitudinal observations were performed cohort 2811 participants no at inception. The rate conversion into NAFLD was 15.7% (440/2811), steady increase prevalence observed sub-cohorts increasing levels. Moreover, regression analysis indicated that levels serve risk factors for...

Obesity is a common chronic disease, and elevated serum uric acid has been suggested to be associated with obesity. However, whether the elevation casual or consequence of obesity remains unclear. We performed study investigate longitudinal association between levels obesity.A total 4411 initially obesity-free subjects were followed up for 9 years. The divided into groups according quartile. Univariable multivariable Cox regression models used analyze risk factors development obesity.Of...

Abstract Traditionally, the RFID technology is generally used for identification of pigs in vivo. However, method electronic ear tags and will cause great pain to pigs, then easily fall off during pig’s activities, increasing operating cost enterprise. This paper uses powerful feature learning expression capabilities convolutional neural networks deep automatically learn facial features pigs. Use Image Data Generator that comes with Keras perform data enhancement on pig face pictures ten...

Background Malnutrition is a rising global health issue associated with unfavorable outcomes of variety disorders. Currently, the prevalence and prognostic significance malnutrition to patients acute coronary syndrome (ACS) chronic kidney disease (CKD) remained largely unclear. Methods A total 705 diagnosed ACS CKD in First Affiliated Hospital Wenzhou Medical University between 2013 2021 were included this retrospective cohort study. was assessed by Controlling Nutritional Status (CONUT),...

Patients with acute myocardial infarction (AMI) and chronic kidney disease (CKD) are at high risk of contrast-induced nephropathy (CIN), which can subsequently worsen the overall prognosis. To evaluate efficacy spironolactone for CIN prevention, 410 patients AMI CKD receiving percutaneous coronary intervention (PCI) were retrospectively analyzed. Among them, 240 170 enrolled in standard treatment groups (spironolactone was administered 2 days before 3 after PCI), respectively. The primary...

Atrial fibrillation (AF) is the most common clinically relevant arrhythmia. AF a strong independent risk factor for subsequent development of heart failure (HF). HF and can interact to perpetuate exacerbate each other. Soluble ST2 (sST2) biomarker cardiomyocyte stretch that useful in diagnosis prognosis HF. Its role field has not yet been well investigated. We studied concentration sST2 cohort 174 subjects (62.1% men; mean age, 65.6 ± 10.3 years [± standard deviation (SD) ]) with nonvalvular...

The speed of flower opening is closely related to their ornamental period. Ethylene functions as a negative regulator involved in the regulation petal expansion process. In this study, we isolated NF-YC transcription factor gene, RhNF-YC9, from rose petals. RhNF-YC9 expression was induced at early stages but inhibited by ethylene treatment. Silencing decreased stage 2 5. expressions 11 cell expansion-related genes wall loosening, turgor modulation, and cytoskeleton remodeling were...

Abstract In cut rose (Rosa hybrida), the flower-opening process is closely associated with vase life. Auxin induces expression of transcription factor genes that function in petal growth via cell expansion. However, molecular mechanisms underlying auxin effect during flower opening are not well understood. Here, we identified auxin-inducible gene RhMYB6, whose level high early stages opening. Silencing RhMYB6 delayed by controlling expansion through down-regulation expansion-related genes....

Flower senescence is genetically regulated and developmentally controlled. The phytohormone ethylene induces flower in rose (Rosa hybrida), but the underlying signaling network not well understood. Given that calcium regulates animals plants, we explored role of petal senescence. Here, report expression calcineurin B-like protein 4 (RhCBL4), which encodes a receptor, induced by petals. RhCBL4 interacts with CBL-interacting kinase 3 (RhCIPK3), both positively regulate Furthermore, determined...

Objective: The purpose of this study is to evaluate the safety and efficacy linaclotide polyethylene glycol (PEG) electrolyte powder in patients with chronic constipation undergoing colonoscopy preparation. Patients Methods: We included 260 who were scheduled undergo a colonoscopy. They equally divided into 4 groups using random number table: 4L PEG, 3L PEG+L, 2L PEG+L. compared based on their scores Boston Bowel Preparation Scale (BBPS) Ottawa Quality (OBPQS), adverse reactions during bowel...

Cultivated roses have the largest global market share among ornamental crops. Postharvest release of ethylene is main cause accelerated senescence and decline in rose flower quality. To understand molecular mechanism ethylene-induced petal senescence, we analyzed transcriptome petals during natural as well with treatment. A large number differentially expressed genes (DEGs) were observed between developmental process. We identified 1207 upregulated process, including 82 transcription factors...

Caged broilers, reared extensively, necessitate timely health assessment to mitigate farming losses. Therefore, accurate detection of broiler status holds a pivotal role in averting avian disease propagation. In this study, we propose method for recognition using YOLOv5′s original structure, augmented with the lightweight mobile-EMO network model. Initially, replace backbone convolutional, pooling, and connectivity layers EMO module, except decoupling header. This substitution crafts an...

An elevated serum uric acid concentration may be associated with hypertension, which is the leading cause of death worldwide. However, whether elevation causal or a consequence hypertension among Chinese population remains unclear. This study was designed to investigate longitudinal relationship between concentrations and individuals. included 5105 subjects, initially without who were followed up for 9 years. The subjects divided into four groups based on quartile. Cox proportional hazard...

Background The prevalence and the spectrum of thyroid dysfunction in mainland China are not adequately understood. We performed a population-based study to determine major dysfunctions including overt subclinical hyper- hypothyroidism stable cohort. Methods All active retired employees aged 20 years older (11 067) Sinopec Zhenhai Refining & Chemical Company Ningbo participated cross-sectional survey with questionnaire blood samples. Results A total 10 405 individuals attended for...