Changfu Zhu

ORCID: 0000-0003-2834-2742
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Photosynthetic Processes and Mechanisms
  • Plant biochemistry and biosynthesis
  • CRISPR and Genetic Engineering
  • Plant tissue culture and regeneration
  • Transgenic Plants and Applications
  • Plant Micronutrient Interactions and Effects
  • Genetically Modified Organisms Research
  • Algal biology and biofuel production
  • Animal Genetics and Reproduction
  • Plant Stress Responses and Tolerance
  • Phytase and its Applications
  • Animal Nutrition and Physiology
  • Plant Virus Research Studies
  • Phytochemicals and Antioxidant Activities
  • Plant Gene Expression Analysis
  • Aquaculture Nutrition and Growth
  • Lipid metabolism and biosynthesis
  • Plant nutrient uptake and metabolism
  • Aluminum toxicity and tolerance in plants and animals
  • Plant Molecular Biology Research
  • Saffron Plant Research Studies
  • Retinoids in leukemia and cellular processes
  • Soybean genetics and cultivation
  • Microbial Metabolic Engineering and Bioproduction

Dalian Medical University
2018-2024

First Affiliated Hospital of Dalian Medical University
2018-2024

Universitat de Lleida
2013-2022

Changchun Normal University
2013-2022

Soochow University
2016-2019

Tongren Hospital
2015

Northeast Normal University
1996-2012

Zhejiang University
2007-2008

The Graduate Center, CUNY
2006

Lehman College
2006

Vitamin deficiency affects up to 50% of the world's population, disproportionately impacting on developing countries where populations endure monotonous, cereal-rich diets. Transgenic plants offer an effective way increase vitamin content staple crops, but thus far it has only been possible enhance individual vitamins. We created elite inbred South African transgenic corn in which levels 3 vitamins were increased specifically endosperm through simultaneous modification separate metabolic...

10.1073/pnas.0901412106 article EN Proceedings of the National Academy of Sciences 2009-04-28

Combinatorial nuclear transformation is a novel method for the rapid production of multiplex-transgenic plants, which we have used to dissect and modify complex metabolic pathway. To demonstrate principle, transferred 5 carotenogenic genes controlled by different endosperm-specific promoters into white maize variety deficient endosperm carotenoid synthesis. We recovered diverse population transgenic plants expressing enzyme combinations showing distinct phenotypes that allowed us identify...

10.1073/pnas.0809737105 article EN Proceedings of the National Academy of Sciences 2008-11-15

The profile of secondary metabolites in plants reflects the balance biosynthesis, degradation and storage, including availability precursors products that affect metabolic equilibrium. We investigated impact precursor-product on carotenoid pathway endosperm intact rice because this tissue does not normally accumulate carotenoids, allowing us to control each component pathway. generated transgenic expressing maize phytoene synthase gene (ZmPSY1) bacterial desaturase (PaCRTI), which are...

10.1111/pbi.12373 article EN other-oa Plant Biotechnology Journal 2015-04-07

The apocarotenoid crocetin and its glycosylated derivatives, crocins, confer the red colour to saffron. Crocetin biosynthesis in saffron is catalysed by carotenoid cleavage dioxygenase CCD2 (AIG94929). No homologues have been identified other plant species due very limited presence of derivatives kingdom. Spring Crocus with yellow flowers accumulate crocins stigma tepals. Four CCDs, namely CaCCD1, CaCCD2 CaCCD4a/b CaCCD4c were first cloned characterized. was localized plastids, a longer...

10.1111/nph.13609 article EN New Phytologist 2015-09-17

Cofactor requirement was determined for the heterologous expressed phytoene desaturases from cyanobacterium Synechococcus and higher plant Gentiana lutea. The cyanobacterial enzyme is dependent on either NAD(P) or plastoquinone, whereas only quinones such as plastoquinone can function a cofactor desaturase G. Enzyme kinetic studies were carried out to determine possible competition between cofactors bleaching herbicide norflurazon. For enzyme, norflurazon NADP, well could be demonstrated....

10.1021/jf0106751 article EN Journal of Agricultural and Food Chemistry 2001-10-19

The aim of this study was to assess whether endosperm-specific carotenoid biosynthesis influenced core metabolic processes in maize embryo and endosperm how global seed metabolism adapted expanded biosynthetic capacity. Although enhancement targeted the kernels, a concurrent up-regulation sterol fatty acid measured. Targeted terpenoid analysis, non-targeted metabolomic, proteomic, transcriptomic profiling revealed changes especially carbohydrate transgenic line. In-depth analysis data,...

10.1093/jxb/erv120 article EN Journal of Experimental Botany 2015-03-20
Coming Soon ...