Introduction. Pregnancy planning is one of the leading areas in population reproductive health care, particular preventing and reducing number abortions. Aim. To evaluate uterine bleeding profile other adverse events associated with use an etonogestrel subcutaneous contraceptive implant (Implanon NXT®). Materials methods. We analysed medical records female patients (n = 153) who used Implanon NXT® period from 2013 to 2023, events, bleeding, management techniques reasons given by women for...

Among gynaecological diseases in women of reproductive age the leading place is occupied by inflammatory lower part genital tract (70%), a significant proportion which are processes vagina and cervix uteri. In ⅔ women, cervicitis most often asymptomatic, so they do not seek medical treatment, 65–77.6% have transition to chronic form. Thus, diagnosed almost one three who assistance from gynaecologist due leukorrhea, there no tendency for decrease frequency. The article presents an actual view...

Background. Pelvic inflammatory disease (PID) is a significant gynecological problem. The main treatment strategy involves antibacterial drugs to eliminate the infection in combination with anti-inflammatory, infusion, transfusion, anticoagulant, and desensitization therapy. Chronic processes can induce changes immune system, thus reducing effectiveness of treatment, causing adhesions, obstruction fallopian tubes, infertility. It emphasizes importance developing new PID methods, including...

Inflammatory pelvic diseases (IPD) are associated with increased incidence of sexually transmitted infections. The modern features the PID course raise question including drugs improving therapy outcomes in combination therapy. development chronic inflammatory processes is accompanied by changes body's immune system, which serves as a basis for developing and finding new therapeutic agents methods that have an effective effect aimed at restoring function impaired human status whole....

Vulvar lichen sclerosus (VLS) is a dermatosis characterized by lymphocytic reaction and genital skin lesions that significantly affects the quality of life. Due to limited efficacy, current treatment options require further improvement in terms new understanding etiopathogenetic mechanisms long-lasting recurrent course disease. Objective. To compare efficacy safety monotherapy with glucocorticosteroids (GCs) combination therapy GCs Superlimf® cream (lanolin vitamin-mineral protein-peptide...

Herpes infection is one of the most common viral infections in man and presents a serious medical social problem. In Russian Federation, incidence genital herpes 2012 amounted to 16.8 per 100 thousand population. The article deals with questions clinic, diagnostics applications antiviral drug immunomodulatory effects treatment recurrent herpes.

The combined hormonal contraceptives are now one of the most effective methods preventing unwanted pregnancies. They provide high contraceptive reliability, accessibility and ease use, reversibility effects, safety use. Modern additional therapeutic prophylactic effects in various conditions. A new oral Qlaira® was developed course thorough scientific studies. article presents experience using a containing estradiol valerate dienogest – (E2V/DNG). observations showed effectiveness,...

The leading role of ovarian steroid hormones in the pathogenesis uterine fibroids is confirmed by epidemiological, clinical and experimental studies. new approaches to treatment this disease may be developed on basis biological genetic mechanisms underlying occurrence development leiomyomas. use ulipristal acetate patients with leiomyoma a promising method for preparing them surgical procedures, but also avoiding related hypoestrogenic conditions, which results improvement women’s quality life.

Vulvovaginal candidiasis (VVC) is one of the most common vaginal infections, representing 40% to 50% all cases infectious vulvovaginitis. Between 70-75% sexually active women experience at least episode VVC in their lifetime, and 8-10% adult have recurrent VVC. The treatment remains as pressing challenges gynecology. share disease event rates high, despite modern medicines used treat various forms

Optimizing the management of patients with HPV-associated cervical diseases remains a priority for modern studies on this issue. The human papillomavirus is divided into two types: high-risk and low-risk types according to its malignant potential cause cancer some other oncological diseases. Human can clear spontaneously in 85-90% cases, but risk intraepithelial neoplasia invasive quite high persistent oncogenic infection. virus presence body tissues cannot be considered as marker...

Premenstrual syndrome is a symptom complex characterized by repeated physical, psycho-emotional, behavioral symptoms that develop into the luteal phase of cycle (2-14 days before menstruation) and disappear with its onset. The basis PMS diagnosis cyclical nature pathological symptoms. established in accordance ICD-10 criteria based on analysis frequency severity over two menstrual cycles. Differential diagnostics PMS, especially most severe form - premenstrual dysphoric disorder, should be...

The review article presents data on the prevalence of candidiasis various localization against history coronavirus infection (COVID-19). predisposing factors for development and recurrence in patients after therapy have been analysed. Candida is one most common pathogens intensive care units (ICUs), affecting 6 to 10% patients, some studies reported an increasing trend candidemia. literature that we analysed showed types fungal among with a severe course COVID-19 were C. albicans, then...

Chronic inflammatory processes are associated with changes in the immune system of body, affecting both process and outcome disease. That is why regimen should include drugs which targeted not only at restoration total status individual or a certain element system, but also providing an effective therapeutic action.

Pelvic inflammatory diseases are represented by a spectrum of upper female genital tract, including any combination endometritis, salpingitis, tubo-ovarian abscess or pelvic peritonitis. No doubt, sexually transmitted diseases, especially N. gоnоrrhоeа and С. trachomatis, play significant role in the development diseases. In many cases micro-organisms constituting vaginal biotop cause (anaerobes, G. vaginalis, Haemophilus influenzae, enteric gram-negative bacilli, Streptococcus agalactiae,...

Aim. To determine the change of lipid levels in cervical epithelial cells during treatment chronic cervicitis and low-grade squamous intraepithelial lesions (LSIL) with 0.1% activated glycyrrhizic acid.
 Materials methods. The prospective cohort study included 40 patients LSIL. Cytological evaluation smears was performed according to Bethesda system (2014). All received Epigen Intim Spray for 18 months. Amplification type-specific DNA fragments human papillomavirus (HPV) (sampling...

The data on managing patients with vulvovaginal atrophy and abnormal cytological results are provided for obstetrician-gynecologists.