A5073011326- Herpesvirus Infections and Treatments
- Vector-borne infectious diseases
- Microbial infections and disease research
- HIV Research and Treatment
- Virus-based gene therapy research
- Clinical Laboratory Practices and Quality Control
- Veterinary Medicine and Surgery
- Veterinary Equine Medical Research
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Adrenal Hormones and Disorders
- Animal Virus Infections Studies
- Animal health and immunology
- Viral gastroenteritis research and epidemiology
- Veterinary Oncology Research
- Reproductive Physiology in Livestock
- Animal Behavior and Welfare Studies
- Diabetes and associated disorders
- Veterinary Pharmacology and Anesthesia
- Rabies epidemiology and control
- Bird parasitology and diseases
- Growth Hormone and Insulin-like Growth Factors
- Effects of Environmental Stressors on Livestock
- Blood groups and transfusion
- Helminth infection and control
University of Zurich
2015-2024
Center for Pediatric Endocrinology Zurich
2019-2021
Goethe University Frankfurt
2012
Since the emergence of coronavirus disease (COVID-19) in late 2019, domestic cats have been demonstrated to be susceptible severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) under natural and experimental conditions. As pet often live very close contact with their owners, it is essential investigate SARS-CoV-2 infections a One-Health context. This study reports first infection cat COVID-19-affected household Switzerland. The (Cat 1) signs an upper tract infection, including...
Background Diagnosis of pheochromocytoma ( PC ) is based on a combination clinical suspicion, finding an adrenal mass, increased plasma, and urine concentrations catecholamine metabolites finally confirmed with histopathology. In human medicine, it controversial whether biochemically testing plasma superior to urine. Objectives To measure urinary catecholamines metanephrines in healthy dogs, dogs , hypercortisolism (HC), nonadrenal diseases (NAD) determine the test best diagnostic...
BackgroundCat allergy in human subjects is usually caused by the major cat allergen Fel d 1 and found approximately 10% of Western population. Currently, there no efficient safe therapy for available. Allergic patients try to avoid cats or treat their symptoms.ObjectiveWe developed a new strategy 1–induced immunizing against own allergen, 1.MethodsA conjugate vaccine consisting recombinant virus-like particle derived from cucumber mosaic virus containing tetanus toxin–derived universal...
Abstract Background Gene expression analysis is an important tool in contemporary research, with real-time PCR as the method of choice for quantifying transcription levels. Co-analysis suitable reference genes crucial accurate normalisation. Reference gene may vary, e.g., among species or tissues; thus, candidate must be tested prior to use studies. The domestic cat study subject both medical research and veterinary medicine. aim present was develop TaqMan ® assays eight potential test their...
Serum protein electrophoresis is a useful screening test in equine laboratory medicine. The method can provide valuable information about changes the concentrations of albumin and alpha-, beta-, gamma-globulins thereby help characterize dysproteinemias patients. Reference values for horses using agarose gel as support medium have not been reported.The purpose this study was to establish reference intervals serum adult assess differences between warm-blooded heavy draught horses. In addition,...
Background Serum lipase activities measured by catalytic assays are claimed to be of limited utility for diagnosing pancreatitis in cats. The Spec fPL assay currently is believed the most sensitive test; however, studies comparing different lacking. 1,2‐o‐dilauryl‐rac‐glycero‐3‐glutaric acid‐(6′‐methylresorufin) ester (DGGR) determination activity has been evaluated dogs, but no information available Objectives To investigate agreement DGGR‐lipase and concentration cats with clinical signs...
Background Spec cPL is the most sensitive and specific test for diagnosing pancreatitis in dogs. Its results have not been compared to those of 1,2‐o‐dilauryl‐rac‐glycero‐3‐glutaric acid‐(6′‐methylresorufin) ester ( DGGR ) lipase assay or abdominal ultrasonography. Objectives To investigate agreement with activity pancreatic ultrasonography dogs suspected pancreatitis. Animals One hundred forty‐two Methods (reference range, 24–108 U/L) were measured using same sample. The time interval...
Background Canine babesiosis, caused by Babesia canis , is a prevalent and clinically relevant disease in Europe. Severe acute babesiosis characterized high mortality but prognosis not always correlated with clinical signs nor the level of parasitemia. Objective This study evaluated prognostic markers associated poor outcomes infections. Animals Methods We compared results routine laboratory profiles, hand‐held lactate glucose analyzer, phase response 2 groups naturally infected dogs (7...
Cytauxzoon spp. infection is believed to be a newly emerging tick-borne disease in felids Europe, with three species of the haemoparasite having recently been differentiated wild felids. In Switzerland, rare infections have documented domestic cats west and northwest country, first which was 2014. The aims present study were: (i) characterize hotspot central Switzerland; (ii) elucidate geographic distribution (iii) assess suspected high-risk populations, such as stray anaemic cats; (iv)...
The i-STAT portable clinical analyzer (PCA) was evaluated for performance in avian species. With the EG7+ cartridge, which provided results hydrogen ion concentration, oxygen tension, carbon dioxide sodium, potassium, ionized calcium, hematocrit, and various calculated parameters, analytical accuracy precision were tested by comparing obtained values to those of established traditional blood gas chemistry analyzers. Deming's regression bias plots used compare with laboratory professionals...
Summary Rabbits absorb more calcium (Ca) from their diet than they require, and excrete surplus via urine, which therefore contains a typical ‘sludge’. This makes rabbits susceptible to Ca‐containing uroliths. But given the Ca content of diets free‐ranging specimens, limited reports urinary sludge contents in lagomorphs, we can suspect that are naturally adapted high loads. We fed four groups New Zealand hybrid [ n = 28, age at start 5–6 weeks) pelleted consisting lucerne hay only (L, 2.32%...
The feline leukemia virus (FeLV) is a gamma-retrovirus of domestic cats that was discovered half century ago. Cats are infected with FeLV may develop progressive infection resulting in persistent viremia, immunodeficiency, tumors, anemia and death. A significant number mount protective immune response suppresses viremia; these regressive characterized by the absence viral replication presence low levels proviral DNA. biological importance latter provirus carriers largely unknown.Here, we...
Cytauxzoonosis is an emerging tick-borne disease of domestic and wild felids. Cytauxzoon felis induces severe often fatal in cats. In Europe, clinical subclinical infections caused by sp. are described. We report the first cases infection cats Switzerland. Clinical laboratory data results PCR analyses were collected from PCR-positive followed for up to 851 days. The three two-month old kittens same litter (Cases 1–3) two adult shorthair 4 5). originated north-west west Cases 1–3 presented...
Canine distemper virus (CDV) is a major pathogen of dogs and wild carnivores worldwide. In Switzerland, in domestic rarely reported. recent years, the import from Eastern Europe to Switzerland has steadily increased. present study, we describe outbreak 15 rescue that were imported Hungary by an animal welfare organisation. The data on vaccination medical history recorded (14 dogs), samples collected investigate CDV vector-borne infections (13 dogs) canine parvovirus infection (12 dogs)....
Candidatus Neoehrlichia mikurensis' is an emerging tick-borne zoonotic agent that primarily affects immunocompromised human patients.Dogs and foxes are frequently exposed to ticks, both species in close proximity humans.This the first study systematically investigate occurrence of 'Candidatus Canidae Europa.We analyzed 1'739 blood samples from dogs Switzerland, Italy, Spain Portugal 162 free-ranging red (Vulpes vulpes) Switzerland.All were tested using a previously described multiplex...
Abstract Background Acidification of equine urine to promote dissociation ion complexes is a common practice for concentration measurements. The objective this study was evaluate the effect acidification and storage after on calcium (Ca), magnesium (Mg) phosphate (P) concentrations fractional excretion (FE) these electrolytes. Thirty-two fresh samples were analysed between December 2016 July 2020. Complete urinalysis (stick sediment) performed all samples. Ca, Mg, P creatinine measured in...