Periostin is a matricellular protein, and its synthesis in airway epithelial cells lung fibroblasts induced by interleukin (IL)-4 IL-13. The significance of periostin as biomarker TH 2-induced inflammation, (importantly) measure the response to 2-targeted therapy, has recently been emphasized. We explored relationship between hyperresponsiveness (AHR) asthmatic children.The study included 83 children aged 6-15 years an group (n = 54) healthy controls 29). measured levels serum performed...

Abstract This study aimed to investigate the possible changes in anterior chest tightness after breast cancer surgery. We also try whether is associated with upper-limb dysfunction Eighty-three women who underwent surgery were evaluated before and 2 weeks, 3 months, 9 months Anterior was measured using length of pectoralis minor muscle through methods (length from coracoid process fourth rib linear distance table posterior acromion supine position). Shoulder range motion K-DASH (Korean...

We aimed to investigate the association between smoking status and all-cause mortality of Parkinson's disease (PD). Among whole nationwide population data from Korea National Health Insurance Service, newly diagnosed PD was selected, evaluated. The systematic review performed through a literature search on PubMed, EMBASE, Cochrane Central Register Controlled Trials databases. 26,080 individuals with PD, there no significant in cohort study (ex-smoker, HR 0.1.03, 95% CI 0.97-1.10; current...

Rehabilitation training is essential for a successful recovery of upper extremity function after stroke. Training programs are typically conducted in hospitals or rehabilitation centers, supervised by specialized medical professionals. However, frequent visits to can be burdensome stroke patients with limited mobility. We consider self-administered system based on mobile application which periodically upload videos themselves performing reach-to-grasp tasks receive recommendations...

Post-stroke spasticity is a common complication that limits the functional performance of patients. Botulinum toxin (BTx) an effective treatment for spasticity. Numerous researchers have applied extracorporeal shock wave therapy (ESWT) to address post-stroke spasticity, yielding positive clinical outcomes. We aimed clarify add-on effects ESWT on BTx in patients with post-stroke. Sixteen eligible upper extremity after stroke were recruited this study. They randomized either focused group or...

This study aimed to explore the production of familiar expressions (e.g. idioms, proverbs and pause fillers), including different subtypes, their variation across types elicited discourse in individuals with aphasia due left hemisphere damage (LHD) those right (RHD) healthy control (HCs). Twenty-nine (12 LHD, 8 RHD 9 hCs) provided samples during four tasks (free speech, picture description, story narrative procedural tasks) from TalkBank (AphasiaBank RHDBank). Familiar were categorised into...

Ultrasound-guided cervical nerve root block (US-CRB) is considered a safe and effective method for the treatment of radicular pain. However, previous studies on spreading pattern injected solution in US-CRB have reported conflicting results. The aim this study was to investigate relation injection volume.An institutional, prospective case series.A university hospital.Fifty-three patients diagnosed with mono-radiculopathy C5, 6, or 7.US-CRB fluoroscopic confirmation performed. After roots...

Abstract Temporal parameters during swallowing are analyzed for objective and quantitative evaluation of videofluoroscopic studies (VFSS). Manual analysis by clinicians is time-consuming, complicated prone to human error interpretation; therefore, automated using deep learning has been attempted. We aimed develop a model the automatic measurement various temporal learning. Overall, 547 VFSS video clips were included. Seven manually measured two physiatrists as ground-truth data: oral phase...

Objective To verify the utility of lateral femoral cutaneous nerve (LFCN) ultrasound-guided conduction technique compared to that conventional technique. Methods Fifty-eight legs 29 healthy participants (18 males and 11 females; mean age, 42.7±14.9 years) were recruited. The was performed bilaterally. LFCN localized by ultrasound. Cross-sectional area (CSA) distance between anterior superior iliac spine (ASIS) measured. study repeated with corrected cathode location. Sensory action...

The aim of this study was to measure the degree movement ulnar nerve in cubital tunnel using sonography patients with neuropathy at elbow compared a healthy control group.We examined extended and then flexed 26 13 participants. distance from skin, medial epicondyle, tip olecranon inlet skin recess outlet were measured when flexed, respectively. Displacement during extension flexion between controls compared.There significantly greater displacement epicondyle (mean ± SD, 4.22 3.79 mm) (1.76...

We aimed to investigate the association of various mental illnesses, including depression, bipolar disorder, schizophrenia, insomnia, and anxiety, with risk early-onset Parkinson's disease (EOPD) (age <50 years) compare it that late-onset PD (LOPD) ≥50 years). This nationwide cohort study enrolled 9,920,522 people who underwent a national health screening examination in 2009, followed up until 31 December 2018. There was significantly increased EOPD LOPD individuals illness, showed stronger...

We present an unusual case of a 26-year-old man with muscular polyarteritis nodosa (PAN) severe calf pain and gait disturbance. Magnetic resonance imaging the lower limbs demonstrated highly increased signal intensity in both soleus muscles lateral head left gastrocnemius muscle. Biopsies muscle showed acute necrotizing arteritis. The limited range motion ankle dorsiflexion subsided from day 1 on administration oral corticosteroid at high dosage were completely resolved by 4 months. After...

Abstract L1 radiculopathy is very rare and difficult to diagnose with needle electromyography. A patient presented pain hypesthesia on the anterolateral aspect of left thigh. Nerve conduction studies electromyography were normal, except for quadratus lumborum iliopsoas muscles, which showed abnormal spontaneous activity polyphasic motor unit potentials reduced recruitment patterns. Magnetic resonance imaging lumbar spine disc extrusion L1–2 intervertebral space upward migration. This case...

Lofgren's syndrome is an acute form of sarcoidosis characterized by erythema nodosum, bilateral hilar lymphadenopathy (BHL), and polyarthralgia or polyarthritis. This common among Caucasians but rare in the Korean population. A 44-year-old woman was admitted to our hospital complaining polyarthralgia. chest radiograph revealed BHL nodular shadows. Angiotensin-converting enzyme levels were within normal range. Tissue biopsy from a mediastinum lymph node showed noncaseating granulomas. We...

Introduction High resolution ultrasonography (US) has been used for diagnosis and evaluation of entrapment peripheral neuropathy. Ulnar neuropathy at the elbow (UNE) is second most common focal The ulnar nerve tends to move anteromedial side sometimes subluxates or dislocates over medial epicondyle as flexed. Dislocation during flexion may contribute friction injury. We aimed investigate effects which dislocation could have on electrophysiologic pathology UNE. Materials retrospectively...

Abstract Although many studies have been conducted on machine learning (ML) models for Parkinson’s disease (PD) prediction using neuroimaging and movement analyses, with large population-based datasets are limited. We aimed to propose PD ML algorithms based the National Health Insurance Service-Health Screening datasets. selected individuals who participated in national health-screening programs &gt; 5 times between 2002 2015. was defined ICD-code (G20), a matched cohort of without 1:1...

Abstract The purpose of this study was to identify differences in temporal parameters correlating the presence aspiration and severity penetration-aspiration scale (PAS) patients with dysphagia after stroke. We also investigated whether there a significant difference based on location stroke lesion. A total 91 patient videofluoroscopic swallowing (VFSS) videos were retrospectively analyzed. Various including oral phase duration, pharyngeal delay time, response transit laryngeal vestibule...

Objective To evaluate the risk of phrenic nerve injury during ultrasound-guided stellate ganglion block (US-SGB) according to sonoanatomy nerve, and determine a safer posture for needle insertion by assessing its relationship with surrounding structure positional change. Methods Twenty-nine healthy volunteers were recruited underwent ultrasound in two postures, i.e., supine position neck extension head rotation, lateral decubitus position. The transducer was placed at anterior tubercle C6...

To evaluate the relationship between palmar cutaneous branch of median nerve (PCBMN) and surrounding anatomical structures by using high-resolution ultrasound (HRUS) to assess risk PCBMN injury.The course characteristics bilateral distal forearms wrists 30 healthy volunteers were identified. The distance other at three different levels along its measured HRUS. Moreover, depth from skin cross-sectional area (CSA) measured.HRUS showed in all subjects. branched off radial aspect (MN) 4.69±0.89...