A5059340130- Intraoperative Neuromonitoring and Anesthetic Effects
- Spinal Fractures and Fixation Techniques
- Stroke Rehabilitation and Recovery
- Dysphagia Assessment and Management
- Meningioma and schwannoma management
- Botulinum Toxin and Related Neurological Disorders
- Muscle Physiology and Disorders
- Spine and Intervertebral Disc Pathology
- Nerve Injury and Rehabilitation
- Cerebral Palsy and Movement Disorders
- Anesthesia and Pain Management
- Spinal Cord Injury Research
- Voice and Speech Disorders
- Hereditary Neurological Disorders
- Muscle activation and electromyography studies
- Cervical and Thoracic Myelopathy
- Facial Nerve Paralysis Treatment and Research
- Traumatic Brain Injury Research
- Respiratory Support and Mechanisms
- Neurogenetic and Muscular Disorders Research
- Diverse Approaches in Healthcare and Education Studies
- Advanced Neuroimaging Techniques and Applications
- Orthopedic Surgery and Rehabilitation
- Pain Management and Treatment
- Music Therapy and Health
Gangnam Severance Hospital
2013-2024
Yonsei University
2014-2024
Severance Hospital
2008-2021
Sealaska Heritage Institute
2013
Purpose: To investigate the effects of music therapy on depressive mood and anxiety in post-stroke patients evaluate satisfaction levels caregivers.Materials Methods: Eighteen patients, within six months onset mini mental status examination score over 20, participated this study.Patients were divided into control groups.The experimental group program for four weeks.Psychological was evaluated with Beck Anxiety Inventory (BAI) Depression (BDI) before after therapy.Satisfaction by a...
Primary objective: To explore differences in rate of recovery and functional outcome case-matched patients with traumatic (TBI) vs non-traumatic brain injury (non-TBI) during inpatient rehabilitation 1 year post-insult.Research design: Retrospective comparison study case-controlled design.Methods procedures: Demographic data, severity injury, measures outcomes at follow-up were collected on 573 (404 TBI; 169 non-TBI) admitted to a multidisciplinary neurorehabilitation programme. After...
Objective: The objective of this study is to determine the prevalence anterior pituitary dysfunction in moderate-to-severe chronic traumatic brain injury (TBI) patients. investigation a relationship between hormonal status and body mass index (BMI) TBI patients by observing changes BMI was conducted as well an assessment whether there difference functional outcome related patients.Methods: Forty-five 30 normal controls underwent series standard endocrine tests for hormone function. It...
Objective To evaluate whether the combination of muscle motor evoked potentials (mMEPs) and somatosensory (SEPs) measured during spinal surgery can predict immediate permanent postoperative deficits. Methods mMEP SEP was monitored in patients undergoing between November 2012 July 2014. mMEPs were elicited by a train transcranial electrical stimulation over cortex recorded from upper/lower limbs. SEPs stimulating tibial median nerves. Results Combined mMEP/SEP recording successfully achieved...
Objective To identify which combination of motor evoked potentials (MEPs) and somatosensory (SEPs) is most reliable for postoperative deterioration during spinal cord tumor surgery, according to anatomical pathologic type. Methods MEPs SEPs were monitored in patients who underwent surgery between November 2012 August 2016. Muscle strength was examined all before within 48 hours postoperatively 4 weeks later. We analyzed sensitivity, specificity, positive negative predictive values each...
Aim Constraint‐induced movement therapy (CIMT) has emerged as a promising therapeutic strategy for improving affected upper limb function in children with hemiplegic cerebral palsy (CP). However, little is known about the changes brain that are induced by CIMT. This study was designed to investigate these and behavioural performance after CIMT intervention mice neonatal hypoxic‐ischemic injury. Method We utilized injury model established pups. Three weeks injury, were randomly assigned...
Although cultured myoblast transplantation has been extensively studied as a gene complementation approach to muscular dystrophy treatment, clinical success still limited.The inability adequately isolate and purify myoblasts presents major limitation the production of sufficient for engrafting purposes.This study attempted from primary culture by magnetic-activated cell sorting (MACS), complement-mediated cytotoxicity, preplating technique.As result positive selection MACS, average...
The wrist-driven flexor hinge orthosis (WDFHO) is a device used to restore hand function in persons with tetraplegic spinal cord injury by furnishing three-point prehension. We assessed the effectiveness and biomechanical properties of WDFHO 24 cervical 6 or 7 tetraplegia who have severely impaired function. This study introduces mechanical operating model assess efficiency WDFHO. Experimental results showed that pinch force increased significantly (p < 0.001) after using was found...
To investigate a new botulinum neurotoxin type A, termed letibotulinumtoxinA(Botulax®) and compare its efficacy safety for post-stroke upper limb spasticity with that of onabotulinumtoxinA(Botox®).A prospective, double-blinded, multicenter, randomized controlled clinical study.Six university hospitals in Korea.A total 187 stroke participants spasticity.Two kinds A were used. One set injection was performed injected doses 309.21±62.48U(Botulax) 312.64±49.99U(Botox)( P>0.05).Primary outcome...
To evaluate intra-tester reliability of P300 more precisely, this study was designed. Event-related potential (ERP) is the result endogenous brain response following cognitive stimulus. The component human ERP a positive wave with latency 300 ms or greater. Our purpose to estimate and amplitude 30 normal persons without head injury, as well set up them reference values in event that they would be found highly reliable.ERP performed at three separate times on adults their 20s 30s. We measured...
Purpose: Myotonic dystrophy type 1 (DM1) is characterized by progressive muscular weakness with symptoms caused involvement of the brain.The aim this study was to delineate global changes in cortical thickness and white matter integrity patients DM1, compared age-matched healthy controls, brain areas highly correlated CTG repeat size.Materials Methods: Cortical were nine adult DM1 age matched controls using T1-weighted diffusion tensor imaging.The patients' intelligence quotient (IQ) size...
To investigate the predictive value of sympathetic skin response (SSR) in diagnosing complex regional pain syndrome (CRPS) by comparing three diagnostic modalities-SSR, three-phasic bone scans (TPBS), and thermography.Thirteen patients with severe limb were recruited. Among them, 6 diagnosed CRPS according to proposed revised clinical criteria described International Association for Study Pain. SSR was measured either hands or feet bilaterally considered abnormal when latency prolonged. A...
To report successful cases of extubation from invasive mechanical ventilation at our institution using pulmonary rehabilitation consisting noninvasive (NIV) in neuromuscular patients with experience reintubation.Patients who experienced failure via the conventional weaning strategy but afterwards had success NIV were studied retrospectively. Continuous end-tidal CO2 (ETCO2) and pulse oxyhemoglobin saturation (SpO2) monitoring performed. Extubation was defined as a state not requiring...
Bronchiolitis obliterans (BO) is a late onset complication of allogeneic hematopoietic stem cell transplantation (HSCT), and treatment outcome dismal if it does not respond to immunosuppressive therapy.A 21-year-old male diagnosed with acute myeloid leukemia received an HSCT from human leukocyte antigen-identical sibling donor.Twenty one months after transplantation, he developed progressive dyspnea was BO.Despite standard therapy, the patient rapidly progressed respiratory failure Novalung...
Purpose: For patients with neuromuscular disease, air stacking, which inflates the lungs to deep volumes, is important for many reasons.However, severe glottic dysfunction or indwelling tracheostomy tubes cannot stack effectively.For these patients, we developed a device that permits lung insufflations substituting function.Materials and Methods: Thirty-seven bulbar-innervated muscle weakness and/or tracheostomies were recruited.Twenty-three had amyotrophic lateral sclerosis, 14 tetraplegic...
This case report describes a severe nerve injury to the right ulnar nerve, caused by bee venom acupuncture. A 52-year-old right-handed man received acupuncture on medial side of his elbow and forearm, at Traditional Korean Medicine (TKM) clinic. Immediately after acupuncture, patient experienced pain swelling elbow. There was further development weakness little finger, sensory changes dermatome hand. The visited our clinic 7 days Electrodiagnostic studies 2 weeks showed damage. underwent...