A5100428899- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Intraoperative Neuromonitoring and Anesthetic Effects
- Nerve Injury and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Spinal Fractures and Fixation Techniques
- Anesthesia and Pain Management
- Trauma Management and Diagnosis
- Cardiovascular Syncope and Autonomic Disorders
- Myofascial pain diagnosis and treatment
- Sports injuries and prevention
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Ubiquitin and proteasome pathways
- Cervical and Thoracic Myelopathy
- Meningioma and schwannoma management
- Endometrial and Cervical Cancer Treatments
- Pain Management and Treatment
- Abdominal Trauma and Injuries
- Tendon Structure and Treatment
- Ovarian cancer diagnosis and treatment
- Minimally Invasive Surgical Techniques
- Sympathectomy and Hyperhidrosis Treatments
- Bone Tissue Engineering Materials
Korea University of Science and Technology
2023-2025
Kangwon National University
2009-2025
Duke University
2023-2025
Korea Research Institute of Standards and Science
2025
Sungkyunkwan University
2003-2025
Yonsei University
2015-2024
Gangnam Severance Hospital
2015-2024
ABL Bio (South Korea)
2024
Jeonbuk National University
2015-2024
Bio-Medical Science (South Korea)
2023
To examine the regulatory role of interleukin-22 (IL-22) in expression RANKL and induction osteoclastogenesis rheumatoid arthritis (RA).Concentrations IL-22 serum synovial fluid RA patients were measured using enzyme-linked immunosorbent assay. fibroblasts treated with recombinant human (rhIL-22), messenger RNA (mRNA) protein was real-time polymerase chain reaction, Western blotting, intracellular immunostaining. Human monocytes cocultured IL-22-prestimulated macrophage colony-stimulating...
Abstract Objective To determine whether dietary interventions that increase n-3 fatty acids with and without reduction in n-6 linoleic acid can alter circulating lipid mediators implicated headache pathogenesis, decrease adults migraine. Design Three arm, parallel group, randomized, modified double blind, controlled trial. Setting Ambulatory, academic medical center the United States over 16 weeks. Participants 182 participants (88% women, mean age 38 years) migraines on 5-20 days per month...
The Plasmodium proteasome emerges as a promising target for anti-malarial drug development due to its potential activity against multiple life cycle stages. In this investigation, comparative analysis was conducted on the structural features of β5 subunit in 20S proteasomes both and humans. findings underscore diversity inherent proteasomes. human reveals composition rich β-sheets adopts more compact conformation. This arrangement limits ligand binding pocket's capacity accommodate only...
Aldose reductase plays a central role in diabetes mellitus (DM) associated complications by converting glucose to sorbitol, resulting harmful increase of reactive oxygen species (ROS) various tissues, such as the heart, vasculature, neurons, eyes, and kidneys. We employed comprehensive approach, integrating both ligand- structure-based virtual screening followed experimental validation. Initially, candidate compounds were extracted from extensive drug chemical libraries using DeepChem's...
Biomechanical studies suggest a suture bridge technique enhances rotator cuff tendon footprint contact area, holding strength, and mean pressure. Based on these studies, we asked whether (1) the would provide high rate of integrity after surgery, (2) status repaired change with time, (3) preoperative factors could predict postoperative integrity, (4) patients retears had less favorable pain, functional scores, range motion (ROM), muscle strength compared those intact repairs. We...
The purpose of this study was to examine the effects mirror therapy on upper-extremity function and activities daily living in chronic stroke patients. [Subjects Methods] Fifteen subjects were each assigned a group sham group. Fugl-Meyer Motor Function Assessment Box Block Test performed compare paretic hand coordination abilities. functional independence measurement conducted abilities perform living. [Results] Paretic significantly different between groups. Intervention more effective than...
Biphasic calcium phosphate (BCP) is the most frequently used synthetic bone substitutes, which comprises a combination of hydroxyapatite (HA) and beta-tricalcium (b-TCP). Thanks to recent advances in digital dentistry three-dimensional (3D) printing technology, block substitutes can be customized fit individual defect morphologies. The diameter pores influence rate formation material resorption. aim this study was compare three-dimensionally printed biphasic with different pore diameters...
Background:The aim of this prospective randomized clinical trial was to investigate the effi cacy a home-based program isometric strengthening exercises for treatment lateral epicondylitis (LE) distal humerus.We hypothesized that 1) use would result in benefi ts similar those provided by medication and pain relief 2) functional improvements after exercise be time-dependent. Methods:Patients were assigned one two groups: an immediate physical therapy group (group I), or delayed D).Group I...
Previous studies on massive rotator cuff tears have not addressed the outcomes of extending to subscapularis tendon.The retear rate in patients with a posterosuperior tear combined is higher than that an intact tendon.Cohort study; Level evidence, 3.Data were collected and analyzed from 92 consecutive who underwent arthroscopic repair tear. Patients divided into 3 groups according status tendon: tendon (I-massive tear; n = 42), involving half or less (S-massive 22), more (L-massive 28). The...
Although approximately 100 deubiquitinating enzymes (DUBs) are encoded in the human genome, very little is known about DUBs that function mitosis. Here, we demonstrate DUB USP35 functions as a mitotic regulator by controlling protein levels and downstream signaling of Aurora B depletion eventually leads to several defects including cytokinesis failures. binds deubiquitinates B, inhibits APCCDH1-mediated proteasomal degradation thus maintaining its steady-state during In addition, loss...
Blunt traumatic diaphragmatic rupture (BTDR) is uncommon, but associated with high rates of morbidity and mortality. The purpose this study was to present our experience management injury. Medical records 38 patients BTDR who were treated in hospital from January 2001 June 2016 analyzed retrospectively. sex, age, cause injury, location rupture, mode diagnosis, time the presence herniation bowel perforation, preoperative shock intubation, Injury Severity Score (ISS), injuries, comorbidity,...
Obturator hernia is a relatively rare type of abdominal hernia, in which contents protrude through the obturator canal, condition that can lead to small bowel obstruction. Its rarity and nonspecific signs symptoms make preoperative diagnosis difficult. The present study analyzed clinical manifestations, diagnostic methods operative treatment outcomes patients with hernia.Between January 2012 October 2019, 1028 adults underwent surgical repair wall at Department Surgery, Kyungpook National...