Bioactive barrier membranes aim to actively contribute bone formation by promoting cell proliferation, differentiation, and mineral deposition into defects. Unlike traditional membranes, they can promote growth releasing ions, fostering an optimal environment for GBR. In this study, we aimed investigate the preclinical behavior of PBAT/BAGNb in a critical-sized defect model rat calvaria. A flexible resorbable polyester (poly(butylene adipate-co-terephthalate)) (PBAT) was combined with 30 wt...

Bone grafts are widely used in oral and maxillofacial reconstruction. The influence of electromagnetic fields magnets on the endogenous stimulation target tissues has been investigated. This work aimed to assess quality bone healing surgical cavities filled with autogenous grafts, under a permanent magnetic field produced by vivo buried devices. Metal devices consisting commercially pure martensitic stainless steel washers titanium screws were employed. Thirty male Wistar rats divided into 3...

Objective: The purpose of this study was to demonstrate the effect low-level laser therapy (LLLT) on peri-implant bone healing process in rabbit mandible. Background data: LLLT has been shown accelerate tissue repair and osseointegration implants placed into tibia. However, beneficial effects have never tested mandible, which would more closely mimic human situation. Materials methods: Twenty-four male New Zealand rabbits were randomly divided four groups six animals each. All had their left...

Abstract This study aimed to evaluate the pre‐clinical behavior of niobium‐containing bioactive glasses (BAGNb) by their ability promote bone repair and regulate alkaline phosphatase (ALP) levels in an animal model. BAGNbs were produced as powders scaffolds surgically implanted femur male rats (Wistar lineage n = 10). Glasses without Nb (BAG) well. The Autogenous Bone (AB) was used a control. After 15, 30, 60 days surgical implantation, blood serum samples collected quantify ALP activity,...

The aim of this study was to investigate, in vivo, the quality bone healing under effect a static magnetic field, arranged inside body. A metallic device developed, consisting two stainless steel washers attached structure with titanium screws. Twenty-one Wistar rats (Rattus novergicus albinus) were used randomized experimental study. Each group had five rats, and animals included as control for each groups. pair metal left femur animal, lightly touching surgically created cavity. In groups,...

Lesions in the floor of mouth can be a challenging diagnosis due to variety pathological conditions that might found this area. Within broad range lesions, attention has addressed those require specific management, such as dermoid cyst (DC) and ranula. Especially pediatric patients, whom failure postpone correct treatment cause sequelae later life. DC, developmental anomaly, is managed primarily by surgical resection. On other hand, ranula pseudocyst may treated marsupialization. This...

The purpose of this study was to assess the systemic effects low-level laser therapy (LLLT) on thyroid gland function and, consequently, calcium regulation - as measured by serum triiodothyronine (T3), thyroxine (T4), and free levels when administered after dental implant placement in a rabbit model.Protocols for use several clinical procedures are currently under investigation, not all actions irradiation have been clearly established.Forty male adult New Zealand rabbits were distributed...

Osteoarthritis is a degenerative disease that causes substantial changes in joint tissues, such as cartilage degeneration and subchondral bone sclerosis. Chondroitin sulfate glucosamine are commonly used products for the symptomatic treatment of osteoarthritis. The aim present study was to investigate effects these when structure-modifying drugs on progression osteoarthritis rabbit temporomandibular joint. Thirty-six New Zealand rabbits were divided into 3 groups (n = 12/group): control (no...

Objectives This study aimed to evaluate the potential of adipose-derived stem cells (ASCs) combined with a modified α-tricalcium phosphate (α-TCP) or gelatin sponge (GS) scaffolds for bone healing in rat model. Material and Methods Bone defects were surgically created femur adult SHR rats filled scaffolds, empty ASCs. The results analyzed by histology histomorphometry on days seven, 14, 30, 60. Results Significantly increased repair was observed seven 60 animals treated α-TCP/ASCs, day 14...

The understanding of bone repair phenomena is a fundamental part dentistry and maxillofacial surgery. Objective present study aimed to evaluate the influence buried magnetic field stimulation on in rat calvaria after reconstruction with autogenous grafts, synthetic powdered hydroxyapatite, or allogeneic cartilage without exposure stimulation. Material Methods Ninety male Wistar rats were divided into 18 groups five animals each. Critical defects created rats' immediately reconstructed bone,...

This study aimed to produce poly(butylene adipate-co-terephthalate) (PBAT)/niobium containing bioactive glasses (BAGNb) composites scaffolds produced by fused deposition modeling (FDM) printing and evaluate their physicochemical biological properties in vitro vivo. The composite filaments were melt-extrusion with the addition of 10 wt% BAGNb (PBAT/BAGNb). Filaments without as control group (PBAT). characterized used 3D-printed using FDM. scaffolds' structure surface assessed. In cell,...

Summary This study aimed to assess the effect of zoledronic acid exposure on structures alveolar bone rats. The sample was composed 42 male Wistar Animals in T1 and T2 groups received weekly doses 0.2 mg/kg intraperitoneal for 3 weeks, while animals T3 group same treatment 8 weeks. control C1, C2 C3 equivalent saline. first upper molars rats C2, T2, were extracted. Cone‐beam computerized tomography scans performed, image density analysed by grey levels. presence type inflammatory infiltrate,...

In this study, the biocompatibility, stability and osteotransductivity of a new cement based on alpha-tricalcium phosphate (alpha-TCP) were investigated in bone repair model using rat model. The potential alpha-TCP was compared to autogenous grafting, unfilled cavities used as negative control. Surgical prepared designated test (T), implanted with blocks; control (C - ), unfilled; positive + graft. Results analyzed postoperative days three, seven, 14, 21 60. histological analyses showed...

Ricinoleic acid polyurethane polymer behaviour, implanted subperiostic in rat's mandibular angles was studied. liventy Rattus novergicus (Alhinus rodentia mammalia, cepa Wistar) were divided for groups of five animals each. The polyurethane, added calcium carbonate, at angle them. One animal from and 90 days after surgery. Histological examination showed the stability implant, almost total absence inflammatory response, fibrous capsule formed surrounding bone neoformation. According...

OBJECTIVES: The present study aimed at performing a histological evaluation of the response temporal bone tissue to change direction force vector mandible in relation base skull. MATERIAL AND METHODS: Adult rabbits were assigned into four groups with two control and experimental animals each group. underwent surgery, which resulted on right temporomandibular joint. Samples collected after 15, 30, 60 90 days for analysis. RESULTS: In two-way analysis variance, effect group time was...

Objective: This in vivo experimental study evaluated the effect of methotrexate on oral mucosa mice. Methodology: A total 28 adult BALB/c mice were randomly assigned into a control and an group. Mice group immunosuppressed with 2.5 mg/kg for three consecutive days. One mouse from each was sacrificed day 10 Samples ventral mucosal tongue surface collected prepared histomorphometric analysis, by staining hematoxylin/eosin. Three microscopic fields per section analyzed, order to evaluate mean...

The formation of a Hairy Polyp on the dorsum tongue is rare condition that may hinder vital functions such as swallowing and breathing due to mechanical obstruction. authors present situation child with an approach significant academic value.Imaging diagnostics application topical oral radiocontrastant was used determine extent tumor. Performed treatment complete excision confirmed anatomopathological analysis.The patient controlled for five months and, showing no signs relapse, considered...