A5018733507- Advanced MRI Techniques and Applications
- Synthesis and Catalytic Reactions
- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Analysis
- MRI in cancer diagnosis
- Chemical Synthesis and Reactions
- Oxidative Organic Chemistry Reactions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advanced Neuroimaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Asymmetric Hydrogenation and Catalysis
- Synthetic Organic Chemistry Methods
- Metal-Organic Frameworks: Synthesis and Applications
- Catalytic Cross-Coupling Reactions
- Pancreatic and Hepatic Oncology Research
- Acupuncture Treatment Research Studies
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Covalent Organic Framework Applications
- Pediatric Hepatobiliary Diseases and Treatments
- Synthesis of heterocyclic compounds
- TiO2 Photocatalysis and Solar Cells
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Facial Trauma and Fracture Management
- Sexual Differentiation and Disorders
Guangdong University of Petrochemical Technology
2020-2024
Nankai University
2015-2016
Institute of Organic Chemistry
2015
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2015
Cheng Hsin General Hospital
2014
Imaging Center
2012
Taipei Veterans General Hospital
1993-2004
National Yang Ming Chiao Tung University
1999-2004
National Yang Ming University Hospital
2003
Taipei Hospital
2002
Abstract To determine the feasibility of MR imaging magnetically labeled cells, different cell lines were with monocrystalline iron oxide (MION) particles. Phantoms containing MION cells then assembled and imaged by at 1.5 T using T1‐weighted T2‐weighted pulse sequences. uptake ranged from 8.5 × 10 4 to 2.9 5 particles/cell for tumor (9L LX1, respectively) 6 4.8 8 “professional phagocytes” (J774 peritoneal macrophages, respectively). On images, cell‐internalized appeared hyperintense...
Abstract Cyclic diaryliodoniums are an important class of high‐valent aromatic iodine reagents for the synthesis various axially chiral biaryls and biaryl compounds. Moreover, transition‐metal‐catalyzed annulation has been established construction heterocyclic rings ladder‐type π‐conjugated polycyclic hydrocarbons with readily available cyclic as starting materials. As halogen‐bonding donors, aryliodoniums have explored organocatalysts in a variety organic reactions. In this review,...
CT of Globe Rupture: Analysis and Frequency FindingsWei-Hsin Yuan1,2,3, Hui-Chen Hsu4, Hui-Cheng Cheng4, Wan-Yuo Guo2,3, Michael Mu-Huo Teng2,5, Shih-Jen Chen3,6 Tai-Chi Lin3,6Audio Available | Share
Comprehensive Summary Nitrogen‐containing compounds are ubiquitously found in the fields of organic chemistry, pharmaceuticals, agrochemicals, medicinal chemistry and functional materials. The C—H bond amination reaction is one most straightforward protocols C—N formation, showing "step" "atomic" economy. As a catalyst for reaction, copper exhibits its unique catalytic properties due to easily accessible oxidation states. research progress copper‐catalyzed recent years summarized. At same...
Abstract Images acquired using the TrueFISP technique (true fast imaging with steady‐state precession) are generally believed to exhibit T 2 / 1 ‐weighting. In this study, it is demonstrated that widely used half‐flip‐angle preparation scheme, approaching steady state requires a time length comparable scan such transient‐state response may dominate image contrast. Two‐dimensional images of human brain were obtained various phase‐encoding matrices investigate signal behavior. Contrast between...
To investigate the effects of acupuncture on neural activity detected by use manganese-enhanced functional magnetic resonance imaging (fMRI) and elucidate relationship between somatic acupoint stimulation brain activation.40 New Zealand White rabbits.Manganese-enhanced fMRI was performed in anesthetized rabbits manipulated with electroacupuncture (EA) Zusanli (ST-36) Yanglingquan (GB-34) acupoints. Image acquisition a 1.5T superconductive clinical scanner circular polarized extremity coil....
Abstract Dynamic‐susceptibility‐contrast MR perfusion imaging is a widely used tool for in vivo study of cerebral blood perfusion. However, visualization different hemodynamic compartments less investigated. In this work, independent component analysis, thresholding, and Bayesian estimation were to concurrently segment tissues, i.e., artery, gray matter, white vein sinus, choroid plexus, spinal fluid, with corresponding signal–time curves on images five normal volunteers. Based the...
A general and efficient method for the synthesis of tertiary amides has been developed <italic>via</italic> copper-catalyzed aerobic oxidative amidation amines.
A series of novel indole derivatives containing α-aminophosphonate moieties were synthesized as antitumor agents. The in vitro cytotoxic activity the compounds was evaluated against human hepatoma cells (HepG2) and gastric cancer (MGC-803) by MTT assay, revealing that most target exhibited moderate to high activities. Among them, compound C5 (IC50 = 34.2 µM) demonstrated superior inhibitory activities HepG2 compared with 5-fluorouracil 78.7 µM). It is noteworthy B7 35.7 displayed higher...
Directing group strategy in transition metal catalyzed sp<sup>2</sup> C–H bond cyanation has contributed to the direct conversion of hydrocarbons cyano-containing compounds. Recent developments metal-mediated using this are reviewed.
Aromatic nitro compounds are of great importance as chemical raw materials and organic synthesis intermediates.Traditional electrophilic nitration is difficult to achieve regioselective nitrification.In recent years, transition-metal-catalyzed C-H bond activation has developed rapidly.Most functional groups can be introduced into specific sites aromatics through the chelation transition metals with directing groups.Directing-group assisted nitration, which catalyzed by palladium, rhodium,...
Dibenzothiophenes are widely used in organic photoactive compounds, dyes, liquid crystals, conducting polymers, pharmaceuticals and other fields.Until now, various approaches for their synthesis have been well-documented, among which the cyclization of C-S bond C-C to achieve construction a five-membered sulfur heterocycle dibenzothiophene structure is most reported.Besides, it also can be realized by formation benzene ring through thiophene/its derivatives four-carbon synthon.The...
Hepatic zonation of cholesterol and glycerolipid synthesis was investigated in regenerating rat livers 24 hr after partial hepatectomy. Tritiated acetate [U-14C]glycerol were injected into rats' peritoneal cavities for a short-term labeling study. Periportal perivenous hepatocytes isolated by digitonin collagenase perfusion. Cholesterol significantly higher periportal the sham-operated (periportal/perivenous = 1.67; p < 0.05). Twenty-four hours hepatectomy, selectively decreased 40% (p 0.01)...
Herein, a series of novel HP-DEMOFs were prepared and employed as catalysts for the heterogeneous styrene oxidation reaction. They exhibited much higher conversion than that microporous Cu-BTC structure under same reaction conditions.
This study investigated one-stop breast screening combining magnetic resonance imaging (MRI) and ultrasound (US) in asymptomatic Asian women.3,586 women (mean age, 45.3 years) were retrospectively analyzed by MRI followed US. US-guided biopsy was performed when the MRI-detected lesion confirmed When not detected on initial US, a second-look US guided findings performed. Then done. MRI-positive US-negative patients up according to size, morphology, mammographic diagnosis.In total, 115...
ABSTRACT Purpose . This study presents 3‐dimensional, contrast‐enhanced, magnetic resonance (MR) angiographic appearances of the carotid artery after stenting. Methods The authors reviewed contrast‐enhanced MR angiograms 18 arteries in 13 patients. These were not stenotic or occluded stented segment, as shown on angio‐grams (11 patients) Doppler images (2 obtained later. Results Five patients had 1 stent each their bilateral arteries. One patient with underwent examination twice different...
RATIONALE AND OBJECTIVES The authors determine the utility of relative blood volume measurements (rBV) using a pool marker for magnetic resonance imaging (MRI) in detection early testicular torsion. METHODS Testicular torsion was induced rats by counterclockwise 720° rotation and fixation testis scrotum. MPEG-PL-DTPA-Gd enhanced MRI (30 µmol Gd/kg bolus injection) performed 1 hour after at 1.5 T fat-suppressed three-dimensional fast spoiled gradient-recalled sequence measurement...