A5023817881- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Advanced Sensor and Energy Harvesting Materials
- Hydrogels: synthesis, properties, applications
- 3D Printing in Biomedical Research
- biodegradable polymer synthesis and properties
- Conducting polymers and applications
- Characterization and Applications of Magnetic Nanoparticles
- Agricultural and Food Sciences
- Tissue Engineering and Regenerative Medicine
- Advanced Polymer Synthesis and Characterization
- Virus-based gene therapy research
- Block Copolymer Self-Assembly
- Ultrasound and Cavitation Phenomena
- Advanced biosensing and bioanalysis techniques
- Graphene and Nanomaterials Applications
- Nanocomposite Films for Food Packaging
- Textile materials and evaluations
- Enzyme-mediated dye degradation
- Advanced Cellulose Research Studies
- Proteins in Food Systems
- Ultrasound and Hyperthermia Applications
- Pineapple and bromelain studies
- Iron oxide chemistry and applications
- Proteoglycans and glycosaminoglycans research
Universidade de São Paulo
2021-2023
Nanomed (Brazil)
2020-2021
Universidade Federal do ABC
2017-2021
We developed a fast, single-step sonochemical strategy for the green manufacturing of magnetite (Fe3O4) magnetic nanoparticles (MNPs), using iron sulfate (FeSO4) as sole source and sodium hydroxide (Na(OH)) reducing agent in an aqueous medium. The designed methodology reduces environmental impact toxic chemical compounds minimizes infrastructure requirements reaction times down to minutes. Na(OH) concentration has been varied optimize final size properties MNPs minimize amount corrosive...
This work reports a pH-triggered release system based on [email protected] mesoporous magnetic nanoparticles ([email protected]2) obtained using simple and rapid ultrasound-assisted method. Performed characterization reveals cores of Fe2.9Mn0.1O4 (38 ± 6 nm) specific loss power values adequate for hyperthermia (463 W/g), surrounded by silica shell (10 2 with large surface area (269 m2 g-1) functionalized hydroxyl groups (-OH). protected]2 were loaded DOX amino-silane grops, providing at...
The development of nanovehicles for intracellular drug delivery is strongly bound to the understating and control nanoparticles cellular uptake process, which in turn governed by surface chemistry. In this study, we explored synthesis, characterization, block copolymer assemblies consisting a pH-responsive poly[2-(diisopropylamino)ethyl methacrylate] (PDPA) core stabilized three different biocompatible hydrophilic shells (a zwitterionic type poly(2-methacryloyloxyethyl phosphorylcholine)...
Abstract The use of sugar‐functionalized polyplexes as a nonviral gene delivery vector with lower cytotoxicity than the well‐known polymeric carrier branched polyethyleneimine (BPEI) is investigated. substitution primary amine groups in BPEI chains lactose residues leads to larger polyplexes, presumably due higher amount polymer required complete DNA condensation. Nevertheless, sugar functionalization substantially reduces assemblies. nanocomplexes are taken up by cells greater extent,...
Hydrogels of poly(vinyl alcohol) (PVA)/sodium alginate (SA), and magnetic nanoparticles (MNPs) were prepared by solvent casting in the absence presence magnets, order to obtain MNPs distributed randomly (PVA/SA-rMNP) magnetically oriented (PVA/SA-gMNP) polymer matrix. Atomic force microscopy (AFM) (MFM) techniques used evaluate topography map distribution domains matrix, respectively. The tip-surface distance (lift distance) 50 nm during MFM analyses facilitated mapping because van der Waals...
Bioactive peptides from natural resources with associated beneficial biological properties such as skin wound healing have drawn much attention. Polysaccharides their biocompatibility, biodegradability, and ease of modification are suitable carriers for delivery to the wound. In this study, a polysaccharide-peptide system was designed potential applications. Xanthan hydrogels were modified yeast-derived peptide VW-9 known via chemical conjugation using carbodiimide chemistry (XG-g-VW-9) or...
This study investigated the physicochemical properties of 3D printed sodium alginate (SA)/poly(vinyl alcohol) (PVA)-magnetic nanoparticle (MNP) hydrogels that were subsequently cross-linked using Ca2+ ions via postspraying. The rheological precursor assessed because they play a crucial role in printability. SA/PVA composition 12/8 wt %, both absence and presence MNPs at concentrations 1.0 mg/mL, 2.5 or 5.0 displayed good Magnetic force microscopy (MFM) evidenced random distribution on...
Failure or loss of human tissues and organs due to illness injury requires the partial even total transplantation. Although transplantation is a successful intervention, donor availability immune rejections represent still main drawbacks. In addition, fast proper recovery patient nowadays more than necessary prevent infection, chronic inflammation, other complications during tissue/organ healing process. There tremendous interest alternatives transplantation, such as scaffold-based tissue...