A5000616017- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Synthesis of Tetrazole Derivatives
- Cancer therapeutics and mechanisms
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Phenothiazines and Benzothiazines Synthesis and Activities
- Multicomponent Synthesis of Heterocycles
- Synthesis and Characterization of Heterocyclic Compounds
- Nanomaterials for catalytic reactions
- Educational and Psychological Assessments
- Crystal structures of chemical compounds
- Advanced Photocatalysis Techniques
- Educational Challenges and Innovations
- Concrete Corrosion and Durability
- HIV/AIDS drug development and treatment
- Education, Literature, Philosophy Research
- Foreign Language Teaching Methods
- Hydrogen embrittlement and corrosion behaviors in metals
- MXene and MAX Phase Materials
- Synthesis of heterocyclic compounds
- Computational Drug Discovery Methods
- Ferrocene Chemistry and Applications
- Corrosion Behavior and Inhibition
- Early Childhood Education and Development
Sidi Mohamed Ben Abdellah University
2019-2025
University of Hassan II Casablanca
2024-2025
The objective of the study was to synthesize tetrazole molecules featuring nitro groups positioned at para and meta locations. We aimed assess their effectiveness in inhibiting corrosion mild steel a 1 M HCl solution 298 K. Tetrazoles with 2,5-disubstitution were created using [3 + 2] cycloaddition N-alkylation techniques, particular emphasis on synthesizing that contain groups. Tafel polarization experiments, which employ curve approach, used inhibition. Furthermore, quantum chemical...
The goal of this study was to synthesize and evaluate new antimicrobial compounds. We specifically focused on the development 2,5-disubstituted tetrazole derivatives containing O-methyl-2,3-O-isopropylidene-(D)-ribofuranoside groups through N-alkylation reactions. synthesized compounds were characterized using 1H 13C nuclear magnetic resonance (NMR) spectroscopy. Their antibacterial activity tested against Pseudomonas aeruginosa, Escherichia coli, Streptococcus fasciens, Staphylococcus...
ABSTRACT While teaching practices are generally known to influence students' motivation, soft skills, and satisfaction, the impact of transformational Teacher Leadership remains underexplored. This study employs a latent growth approach moderated mediation examine skills autonomous motivation (Intrinsic Extrinsic Identified) effects as mediators along with controlled forms (Introjected External) amotivation moderators Transformative on academic satisfaction. Surveys from 204 students across...
Due to the ever-increasing antimicrobial resistance there is an urgent need continuously design and develop novel agents. Inspired by broad antibacterial activities of various heterocyclic compounds such as 2-quinolone derivatives, we designed synthesized new methyl-(2-oxo-1,2-dihydroquinolin-4-yl)-L-alaninate-1,2,3-triazole derivatives via 1,3-dipolar cycloaddition reaction 1-propargyl-2-quinolone-L-alaninate with appropriate azide groups. The were obtained in good yield ranging from 75 80...
This study reports the synthesis of 2-thioxo-1,3-dithiol-carboxamides (TDTCAs) under mild conditions at room temperature using HBTU as a coupling agent, which significantly improved amide bond formation. The synthesized compounds were characterized several analytical techniques, including 1H and 13C NMR spectroscopy, HRMS, confirming their intended structures structural integrity. A DFT computational B3LYP/6-31G(d,p) level was conducted on four to compare electronic properties molecular...
A new series of amino acid derivatives quinolines was synthesized through the hydrolysis methyl esters quinoline carboxamides with alkali hydroxide. The compounds were purified on silica gel by column chromatography and further characterized TLC, NMR ESI-TOF mass spectrometry. All screened for in vitro antimicrobial activity against different bacterial strains using microdilution method. Most acid-quinolines show more potent or equipotent inhibitory action tested bacteria than their...
Ten new quinoline-carboxamides have been synthesized using the coupling reaction between 2-oxo-1,2-dihydroquinoline-4-carboxylic acid as a substrate and five different amino ester at room temperature with basic media (triethylamine). The products were obtained good yield ranging from 60 to 80 % structurally characterized by 1H 13C NMR spectroscopy mass spectrometry. antibacterial activities of compounds evaluated against 9 strains bacteria compared references (erythromycin, ofloxacin,...
The substituted cyclopentadienyl ring in the title molecule, [Fe(C 5 H )(C 18 13 ClN)], is nearly coplanar with phenyl-1-(4-chlorophenyl)methanimine substituent, dihedral angles between planes of phenylene and Cp 4-(chlorophenyl)methanimine units 7.87 (19) 9.23 (10)°, respectively. unsubstituted rotationally disordered, occupancy ratio for two orientations refined to a 0.666 (7)/0.334 (7) ratio. In crystal, molecules pack `bilayers' parallel ab plane ferrocenyl groups on outer faces...