A5102818415- Pituitary Gland Disorders and Treatments
- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Adrenal and Paraganglionic Tumors
- Plant and fungal interactions
- Antimicrobial Resistance in Staphylococcus
- RNA and protein synthesis mechanisms
- Plant Pathogenic Bacteria Studies
- Diphtheria, Corynebacterium, and Tetanus
- Infections and bacterial resistance
- Bacterial Identification and Susceptibility Testing
- Mycobacterium research and diagnosis
- Plant Toxicity and Pharmacological Properties
- Lymphoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Clostridium difficile and Clostridium perfringens research
- Diagnosis and treatment of tuberculosis
- Tuberculosis Research and Epidemiology
- Plant Virus Research Studies
Shenzhen University
2021-2023
Southern Medical University Shenzhen Hospital
2022
Abstract Differentiation between Crohn’s disease and intestinal tuberculosis is difficult but crucial for medical decisions. This study aims to develop an effective framework distinguish these two diseases through explainable machine learning (ML) model. After feature selection, a total of nine variables are extracted, including surgery, abdominal, bloody stool, PPD, knot, ESAT-6, CFP-10, dilatation comb sign. Besides, we compared the predictive performance ML methods with traditional...
Paraclostridium bifermentans (P.b) is an emerging human pathogen that phylogenomically close to Paeniclostridium sordellii (P.s), while their populational genomic features and virulence capacity remain understudied. Here, we performed comparative analyses of P.b compared pan-genomic coding profiles those P.s. Our results revealed has a more plastic pangenome, larger genome size, higher GC content than Interestingly, the P.s share similar core-genomic functions, but encodes functions in...
Prevotella bivia is a species that commonly colonizes various human body sites, and it associated with lots of infections. However, until now, no complete genome sequence this has been published. Here, we assembled the first P. from clinically derived strain PLW0727, to characterize its general genomic features, profile capacity in encoding antibiotic resistance virulence factors.
Abstract Background Enterococcus raffinosus is one of the species that often cause nosocomial infections. To date, only E. genome has been completely assembled, and genomic features have not characterized. Here, we report complete sequence strain CX012922, isolated from feces a Crohn’s disease patient, perform comparative analysis to relevant spp. strains in silico. Results De novo assembly sequencing reads CX012922 generated circular 2.83 Mb megaplasmid 0.98 Mb. Phylogenomic revealed...
Winkia neuii, previously known as Actinomyces is increasingly recognized a causative agent of various human infections, while its taxonomy and genomic insights are still understudied. A strain NY0527 was isolated from the hip abscess patient, antibiotic susceptibility assessed. The genome hybrid assembled long-reads short-reads sequencing. Whole-genome-based analyses on taxa assignment, diversity, pathogenesis were conducted. found to be highly susceptible beta-lactam antibiotics, but...
A 57-year-old woman was admitted to hospital with fever. She still had fever treated multiple antibiotics, and no definite evidence for infection found. Hypothermia hypotension developed, magnetic resonance imaging (MRI) examination showed enlarged anterior pituitary small nodular lesions mild enhancement on the left side. Hormone replacement anti-infection treatment were administrated, but did not improve. Remarkable lymphadenopathy found in supraclavicular area. The pathology of lymph node...