A5041519646- Autoimmune Bullous Skin Diseases
- Research on Leishmaniasis Studies
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Wound Healing and Treatments
- Leprosy Research and Treatment
- Oral and gingival health research
- Nonmelanoma Skin Cancer Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Food Allergy and Anaphylaxis Research
- Diabetic Foot Ulcer Assessment and Management
- Reconstructive Facial Surgery Techniques
- Allergic Rhinitis and Sensitization
- Diagnosis and Treatment of Venous Diseases
- Eosinophilic Disorders and Syndromes
- Hedgehog Signaling Pathway Studies
- Hair Growth and Disorders
- Biomedical Research and Pathophysiology
- Inflammasome and immune disorders
- Asthma and respiratory diseases
- Vascular Malformations and Hemangiomas
- Hematological disorders and diagnostics
- Entomological Studies and Ecology
- Immunodeficiency and Autoimmune Disorders
- Vasculitis and related conditions
Universidade de São Paulo
2012-2025
Universidade de Ribeirão Preto
2012-2024
Clinics Hospital of Ribeirão Preto
2020-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2022
Universidade Estadual de Ponta Grossa
2019
Hospital Universitário da Universidade de São Paulo
2017
Hospital São Paulo
2017
Sensitization to house dust mites (HDMs) is frequent in patients with atopic dermatitis. To investigate the efficacy of sublingual immunotherapy (SLIT) Dermatophagoides pteronyssinus extract dermatitis sensitized HDM. In this randomized, double-blind, placebo-controlled trial, we enrolled 91 3 years or older, SCORing Atopic Dermatitis (SCORAD) score greater than equal 15 and positive skin test result and/or IgE D pteronyssinus. Patients were stratified according age (<12 ≥12 years) receive...
Chronic leg ulcers affect a large portion of the adult population and cause significant social economic impact, related to outpatient hospital care, absence from work, security expenses, reduced quality life. The correct diagnosis therapeutic approach are essential for favorable evolution. To gather experience Brazilian dermatologists, reviewing specialized literature prepare recommendations treatment main types chronic ulcers. Seven specialists six university centers with in were appointed...
Summary Background Cutaneous leishmaniasis (CL) is characterized by immune dysregulation that facilitates chronic infection. Objective To investigate the role of T cells in immunopathology CL characterizing landscape skin lesions using single-cell RNA sequencing (scRNA-seq). Methods We performed scRNA-seq to profile from PBMC and patients. Results analyzed transcriptional distinct populations CD4+ CD8+ migratory lesions. resident displayed expression exhaustion markers were categorized into...
Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening blistering drug reactions with high incidence of ocular sequela. The term 'Epidermal Necrolysis' has been recently used to better describe the full spectrum disease that includes at opposite ends, which differ by extent body surface area detachment. SCORTEN is a mortality prognosis score for cases still needed validation in acquired immunodeficiency syndrome.
Mycobacterium tuberculosis infections can be associated with several immune mechanisms. Some of these mechanisms, such as vasculitis tuberculosis, are rare and challenge dermatologists when making differential diagnoses. The association between pulmonary (Tb) was first described by Parish Rhodes (1) in 1967. These associations fall into three main types: Tb/cutaneous leukocytoclastic (CLV), Tb/Henoch-Schonlein purpura (HSP) Tb/vasculitis secondary to rifampicin (2-7). existence circulating...
Background: Residual tumors increase the likelihood of recurrence basal cell carcinoma (BCC).Objective: We determined attributes and risk factors for positive surgical margins (+SM) excised BCC in a university hospital.Methods: In this cross-sectional retrospective study, we reviewed histologic reports removed via conventional excision (CSE) by specialists from different fields.Results: Among BCCs (n = 864), there was predominance nodular (82.64%) facial H-area (72.81%; average diameter 9.12...
Corticosteroids and/or thalidomides have been associated with thromboembolism events (TBE) in multibacillary (MB) leprosy. This report aimed to determine genetic and laboratory profiles leprosy TBE.Antiphospholipid antibodies (aPL), coagulation-related exams, prothrombin Leiden's factor V mutations, ß2-glycoprotein-I (ß2GPI) Val247Leu polymorphism were assessed.Six out of seven patients treated prednisone thalidomide during TBE presented at least one positive aPL. All ß2GPI polymorphism,...
Mohs micrographic surgery (MMS) promotes high cure rates, but accessibility to MMS is limited in distinctive realities and countries.We sought verify applicable criteria for indication prioritization regarding basal cell carcinoma (BCC) the face of various limitations.We analyzed MMS-excised BBC, without patient exclusion, through a retrospective cohort study at single university center.Mohs was performed 101 BCCs, average size = 5.44 ± 11.91 cm2, 56.44% ≥ 20 mm. Most BCCs were H-zone...
American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports coinfection are scarce.We report a series 9 ATL-leprosy cases discuss the association. An integrative diagram to analyze clinico-immunological features with both diseases.Nine patients (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection distinct clinical forms leprosy. Our diagram-based analysis evidenced divergent spectrum for each disease in 8 out cases.The...
Os autores apresentam análise retrospectiva de 44 pacientes com Polipose Múltipla Familiar tratados no Hospital das Clínicas da Faculdade Medicina Ribeirão Preto,Universidade São Paulo, entre janeiro 1991 a julho 2005. Foram estudados aspectos epidemiológicos (idade, sexo), genéticos, principais sintomas, antecedentes pessoais e envolvendo tratamento cirúrgico complicações pós-operatórias, comparando os achados literatura correlata. Dos pacientes, 31 são do sexo masculino 13 feminino idade...
Abstract Generalized verrucosis is a clinical manifestation of human papillomavirus infection. Patients with generalized present over 20 verrucae distributed various anatomical sites. The disorder occurs in association several genetic syndromes immunodeficiency, including GATA2 deficiency. We report 12‐year‐old boy deficiency and that worsened after cyclosporine use following bone marrow transplant. Systemic treatment acitretin topical application trichloroacetic acid, likely along immune...
Bullous pemphigoid (BP) associated with milia lesions has been increasingly reported, but its prevalence not reported in a Brazilian BP population yet.To describe the occurrence and clinical-laboratorial findings of BP-milia association southeastern sample.A descriptive study based on medical charts 102 patients was accomplished. Clinical laboratory data were compiled. Total serum IgE measurements, immunoblot assays basement membrane zone antigens, HLA-DQ alleles typing performed.Milia...
Pemphigus vulgaris (PV) affects mainly the mucous