Daniel Isika

ORCID: 0000-0003-2874-1903
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About
Contact & Profiles
Research Areas
  • Phytochemicals and Antioxidant Activities
  • Computational Drug Discovery Methods
  • Synthesis and biological activity
  • Medicinal Plants and Neuroprotection
  • Biosensors and Analytical Detection
  • Urbanization and City Planning
  • Advanced Nanomaterials in Catalysis
  • Advanced biosensing and bioanalysis techniques
  • Polydiacetylene-based materials and applications
  • Natural product bioactivities and synthesis
  • Nanoparticles: synthesis and applications

New Jersey Institute of Technology
2020-2022

SMART Global Holdings (United States)
2020-2022

University Heights Center
2020

SMART Reading
2020

Newark Hospital
2020

Center for Integrated Smart Sensors
2020

Palladium is a versatile catalyst, but the synthesis of palladium nanoparticles (PdNPs) usually attained at high temperature in range 160 °C to 200 using toxic reducing agents such as sodium borohydride. We report PdNPs low-cost and environmentally-friendly route ambient temperatures. Quercetin diphosphate (QDP), naturally-derived flavonoid, was employed reducing, capping, stabilizing agent. The effect optimized produce perfectly spherical PdNP with sizes ranging from 0.1 0.3 microns...

10.1039/c9ra07800b article EN cc-by-nc RSC Advances 2020-01-01

This study reports the synthesis and characterization of a novel class flavonoid acetamide derivatives (FA) quercetin, apigenin, fisetin, kaempferol, luteolin.

10.1039/d2ra01375d article EN cc-by-nc RSC Advances 2022-01-01

The interaction of new molecules obtained by the design and synthesis flavonoid derivatives molecular docking with DNA.

10.1039/d0ra04559d article EN cc-by-nc RSC Advances 2020-01-01

The spread and resurgence of the SARS-CoV-2 virus (COVID-19 disease) threatens human health social relations. Prevention COVID-19 disease partly relies on fabricating low-cost, point-of-care (POC) sensing technology that can rapidly selectively detect virus. We report a colorimetric, paper-based polydiacetylene (PDA) biosensor, designed to spike protein in artificial saliva. Analytical characterizations PDA sensor using NMR FT-IR spectroscopy showed correct structural elucidation PCDA-NHS...

10.3390/bios12100804 article EN cc-by Biosensors 2022-09-29

Flavonoids show abundant favorable physicochemical and drug related properties, leading to substantial biological applications which are limited by undesirable properties such as poor solubility, high polarity, low bioavailability, enzymatic degradations. Chemical modification with bioisosteres can be used address some of these challenges. We report the synthesis characterization partial flavonoid acetamide derivatives from quercetin, apigenin luteolin evaluation their structure-activity...

10.3390/molecules27238133 article EN cc-by Molecules 2022-11-22
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