Frank J. Lexa

ORCID: 0000-0003-2877-4422
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About
Contact & Profiles
Research Areas
  • Radiology practices and education
  • Radiation Dose and Imaging
  • Leadership and Management in Organizations
  • Human Resource and Talent Management
  • Healthcare Quality and Management
  • Innovations in Medical Education
  • Healthcare Policy and Management
  • Cerebrovascular and Carotid Artery Diseases
  • Advanced MRI Techniques and Applications
  • Organizational Change and Leadership
  • Healthcare cost, quality, practices
  • Diversity and Career in Medicine
  • Healthcare professionals’ stress and burnout
  • Organizational Leadership and Management Strategies
  • Primary Care and Health Outcomes
  • Cardiovascular Health and Disease Prevention
  • Advanced Neuroimaging Techniques and Applications
  • Acute Ischemic Stroke Management
  • Ethics in medical practice
  • Health and Medical Research Impacts
  • COVID-19 and healthcare impacts
  • Neurological and metabolic disorders
  • Ultrasound in Clinical Applications
  • Disaster Response and Management
  • Management Theory and Practice

UC San Diego Health System
2025

American College of Radiology
2016-2024

University of Pittsburgh
2020-2024

University of Pittsburgh Medical Center
2023-2024

UPMC Health System
2020-2023

Almishkat Centre for Research
2023

University of Pennsylvania
2010-2022

UPMC Presbyterian
2021

Presbyterian Hospital
2021

William P. Wharton Trust
2016-2020

PURPOSE: To assess for the presence of microscopic abnormalities in otherwise normal-appearing white matter on T2-weighted images patients with multiple sclerosis (MS) by using magnetization-transfer (MT) measurements. MATERIALS AND METHODS: Twenty-three MS and nine healthy control subjects underwent magnetic resonance (MR) imaging a 1.5-T system. MT ratios (MTRs) were measured 16 areas identified conventional MS. MTRs same white-matter locations determined. The two groups compared. RESULTS:...

10.1148/radiology.196.2.7617869 article EN Radiology 1995-08-01

Magnetization transfer, a new technique for improving image contrast in magnetic resonance (MR) imaging, is based on application of off-resonance radio-frequency pulses and observing their effects MR images, as well measuring the signal intensity with without (ie, magnetization transfer ratio [MTR]). MTRs can be used to detect changes structural status brain parenchyma that may or not visible standard techniques. Use allow subcategorization multiple sclerosis lesions into those very low MTR...

10.1148/radiographics.14.2.8190954 article EN Radiographics 1994-03-01

Background and Purpose The North American Symptomatic Carotid Endarterectomy Trial (NASCET) demonstrated the benefit of carotid endarterectomy for symptomatic patients with ≥70% stenosis. Screening detection significant occlusive disease has relied on duplex Doppler imaging. However, traditional categories (50% to 79%, 80% 99%) are not directly applicable NASCET. We sought evaluate criteria determination Methods Duplex scans arteriograms 110 (210 carotids), performed within 1 month each...

10.1161/01.str.27.4.695 article EN Stroke 1996-04-01

10.1177/0846537120926752 article EN other-oa Canadian Association of Radiologists Journal 2020-05-12

To determine the typical magnetic resonance (MR) signal intensity characteristics of rhabdomyosarcomas, short repetition time (TR)/short echo (TE) (T1-weighted) and long TR (proton density T2-weighted) images 13 patients with rhabdomyosarcomas head neck were retrospectively reviewed. Seven received gadopentetate dimeglumine injections. The most common MR appearance was that a homogeneous mass, hyperintense to both muscle fat on TR/long TE isointense or minimally TR/short images. All lesions...

10.1148/radiology.177.3.2243968 article EN Radiology 1990-12-01

Magnetization transfer imaging (MTI) has been shown to be sensitive for the detection of white matter abnormalities in entities such as multiple sclerosis, progressive multifocal leukencephalopathy, and wallerian degeneration. Our hypothesis was that MTI would detect traumatic (TWMA) provide information additional obtainable with routine spin- gradient-echo imaging. We hypothesized presence TWMA defined by correlate outcome following TBI. Twenty-eight victims head trauma 15 normal controls...

10.1002/(sici)1522-2586(200001)11:1<1::aid-jmri1>3.0.co;2-h article EN Journal of Magnetic Resonance Imaging 2000-01-01

This study aims to analyze the gap between number of radiologist jobs listed in a single major US job posting center and anticipated graduating general diagnostic radiology neuroradiology trainees through National Resident Matching Program as primary source radiologists fulfill workforce needs. Job listings 2014-2023 from large listing were collected for total unique annual listings, divided neuroradiology-only, some component neuroradiology, no neuroradiology. data PGY-2 Diagnostic...

10.3174/ajnr.a8764 article EN American Journal of Neuroradiology 2025-04-07

The authors studied a carefully screened pool of healthy adult volunteers aged 20-80 years, so that normal brain deep gray matter hypointensity map, as detectable on routine spin-echo magnetic resonance (MR) images, could be formulated. Previous MR imaging studies about iron reported findings either in children only or adults, all whom had suspected central nervous system disease. results showed (a) areas the red nucleus, substantia nigra, and dentate nucleus were relatively unchanged...

10.1148/radiology.181.3.1947087 article EN Radiology 1991-12-01

<h3>BACKGROUND AND PURPOSE:</h3> Neuroradiologists have faced continuously increasing clinical workloads. Our aim was to establish and report a baseline survey of the current neuroradiology work environment in United States experiential changes recent years. <h3>MATERIALS METHODS:</h3> A voluntary sent practicing out-of-training members American Society Neuroradiology States. Selected measures included workday volume length, burnout symptoms, participation academic practice-building duties;...

10.3174/ajnr.a5215 article EN cc-by American Journal of Neuroradiology 2017-05-18

Extracranial atherosclerotic carotid artery disease: evaluation of non-breath-hold three-dimensional gadolinium-enhanced MR angiography.F Slosman, A H Stolpen, F J Lexa, M D Schnall, C P Langlotz, Carpenter and I GoldbergAudio Available | Share

10.2214/ajr.170.2.9456971 article EN American Journal of Roentgenology 1998-02-01

Objective Our goal was to assess whether significant secondary atherosclerotic changes from radiation can be detected on SE MR of the neck. Materials and Methods Pre- postradiation scans 16 patients with head neck malignancies were studied randomly, independently, blindly by two readers determine frequency narrowing carotid arterial lumen obliteration space within sheath. Results Interval either common, internal, or external artery seen in 108 192 (56%) vessels evaluated compared...

10.1097/00004728-199407000-00003 article EN Journal of Computer Assisted Tomography 1994-07-01

A three-year-old, female Labrador retriever was presented for acute generalized seizures. Disseminated cryptococcosis with central nervous system (CNS) involvement diagnosed by serum and cerebrospinal fluid (CSF) fungal titers, histopathological examination, magnetic resonance imaging (MRI). Fluconazole therapy resulted in prolonged, substantial clinical improvement a period of one year. This report documents the diagnosis case cryptococcal meningoencephalitis its management new antifungal...

10.5326/15473317-34-2-145 article EN Journal of the American Animal Hospital Association 1998-03-01
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