A5047007097- Paraoxonase enzyme and polymorphisms
- Bone health and treatments
- Bone Metabolism and Diseases
- Parathyroid Disorders and Treatments
- Antioxidant Activity and Oxidative Stress
- Rheumatoid Arthritis Research and Therapies
- Folate and B Vitamins Research
- Systemic Lupus Erythematosus Research
- Chronic Kidney Disease and Diabetes
- Atherosclerosis and Cardiovascular Diseases
- Biomarkers in Disease Mechanisms
- Retinal Diseases and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Renal Diseases and Glomerulopathies
- Lipoproteins and Cardiovascular Health
- Iron Metabolism and Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Trace Elements in Health
- Vitamin D Research Studies
- Autoimmune and Inflammatory Disorders Research
- Cancer, Lipids, and Metabolism
- Renal Transplantation Outcomes and Treatments
- Medicinal Plants and Bioactive Compounds
- Adipokines, Inflammation, and Metabolic Diseases
- Dialysis and Renal Disease Management
Tabriz University of Medical Sciences
2015-2024
Biotechnology Research Center
2013-2024
University of Tabriz
2013-2020
International Drug Development
2012
Medical University of Silesia
2006
Maastricht University Medical Centre
2006
University of Applied Science and Technology
2006
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2006
Heinrich Heine University Düsseldorf
2006
Düsseldorf University Hospital
2006
Empagliflozin, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor, possesses verified anti-inflammatory and anti-oxidative stress effects against diabetic nephropathy. The present investigation aims to examine empagliflozin on the renal levels of high mobility group box-1 (HMGB1), potent inflammatory cytokine, its respective receptor toll-like receptor-4 (TLR-4) in STZ-induced rats.Empagliflozin at 10 mg/kg per os (p.o.) was administered for 4 weeks, starting 8 weeks after induction...
Hyperlipidemia can lead to atherosclerosis by lipoprotein deposition inside the vessel wall and oxidative stress induction that leads formation of atherosclerotic plaque. Oxidized low-density particles (Ox-LDL) have a key role in pathogenesis atherosclerosis. The lipid-lowering properties antioxidants grape seed be beneficial prevention. We conducted randomized double-blind placebo-controlled crossover clinical trial. Fifty-two mildly hyperlipidemic individuals were divided into two groups...
Abstract Objective The aim of this study was to characterize the status vitamin D in patients with active and recently diagnosed Behcet's disease ( BD ) relationship between levels activity. Methods materials In cross sectional 48 47 age‐ sex‐matched healthy controls were included. by International Criteria for . new cases who not on any treatment. activity measured Iranian Disease Dynamic Activity Measure IBDDAM Current Form BDCAF ). 25( OH )D enzyme‐linked immunosorbent assay method as an...
Purpose: To evaluate the effects of onion juice on sodium-selenite induced cataract formation. Materials and Methods: Thirty-two 10-day-old Wistar-albino rat pups were divided into four equal groups. Group 1 received only subcutaneous saline injection. In 2, (30 nmol/g body weight) was injected subcutaneously. 3, one drop 50% diluted fresh crude instilled every 8 h right eye for 14 days; left no treatment. 4 rats similar to those difference being that undiluted onion. The development...
Red grape seed extract (RGSE) contains oligomeric proanthocyanidin complexes as a class of flavonoids. These compounds are potent antioxidants and exert many health-promoting effects. This study aimed to determine the effects RGSE on serum levels triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL-C), low-density (LDL-C), apolipoprotein AI (apo-AI) paraoxonase (PON) activity in patients with mild moderate hyperlipidemia (MMH).A randomized double-blind placebo-controlled...
Background and Aims: Patients on maintenance hemodialysis (HD) face an increased risk of atherosclerosis, a crucial problem the leading cause cardiovascular morbidity mortality. This study was designed to evaluate effects zinc supplementation paraoxonase (PON) enzyme activity in patients HD. Methods: double-blind randomized controlled trial conducted from June 2005 2007. Sixty HD were enrolled divided into two groups: treatment (case) control. The control groups treated with 100 mg/day or...
Objectives:The purpose of the present study was to determine alterations in high-sensitivity C-reactive protein and Tumor Necrosis factor alpha levels blood serum pseudoexfoliation syndrome cases (a disease with similar risk factors as systemic endothelial dysfunction diseases) compare results healthy individuals.Methods: High-sensitivity were determined 30 control patients same age sex, by enzyme-linked immunosorbent assay. Results:The (3.95±0.88mg/l, 3.32±0.99pg/ ml, respectively)...
The present study aimed to evaluate serum YKL-40 levels in patients with rheumatoid arthritis (RA) compared healthy subjects and search whether there is an association between disease characteristics RA.In this cross-sectional study, 60 RA based on the ACR/EULAR 2010 criteria 30 age- sex-matched controls were included. In patients, clinical examination was performed activity score 28 (DAS-28) measure of assessed. Serum level measured using ELISA kit.The mean±SD age 54.86±11.65 50.71±3.72...
Objective: Behcet's disease (BD) is an inflammatory and smoking may have a role in its triggering. This case-control study was conducted to investigate the association between risk of BD. Methods: We included 192 patients with BD 822 healthy siblings patient 373 unrelated persons as control groups. Demographic data history their were obtained by direct some cases telephone interview participants. controls interview. Propensity score matching (PSM) analyses for reducing heterogeneity studied...
Recurrent aphthous stomatitis (RAS) is characterized by recurrent, painful, shallow, round or oval oral ulcers surrounded inflammatory halos. To investigate the status of vitamin D in RAS patients and relationship between levels severity RAS. In this cross sectional study 46 with idiopathic minor (MIRAS), 49 age sex matched healthy controls were included. Patients at least 3 a year without any known cause for determined as recurrent stomatitis. The was assessed number each attack frequency...