A5112402669- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Neurogenetic and Muscular Disorders Research
- Genetics and Neurodevelopmental Disorders
- Obstructive Sleep Apnea Research
- Child and Adolescent Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Contact Dermatitis and Allergies
- Airway Management and Intubation Techniques
- Ethics and Legal Issues in Pediatric Healthcare
- Emergency and Acute Care Studies
- Child Nutrition and Feeding Issues
- Lymphatic Disorders and Treatments
- Childhood Cancer Survivors' Quality of Life
- Mobile Health and mHealth Applications
- Cardiovascular Syncope and Autonomic Disorders
- Respiratory viral infections research
- Genetic Syndromes and Imprinting
- Infant Health and Development
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2025
Bambino Gesù Children's Hospital
2016-2025
Abstract Background During the pandemic, pneumology team at Bambino Gesù Children’s Hospital highlighted that telemedicine was a valuable tool for remotely managing medical needs of children with complexity (CMC). Following experience during emergency phase, service established, and new tools were tested to optimize televisits overall eHealth approach patients. In this context, TytoHome™ device performing objective examinations remotely. This pilot study, conducted our hospital, explored...
Abstract Background X-linked myotubular myopathy (XLMTM) is a rare congenital resulting from pathogenic variants in the MTM1 gene. Affected male subjects typically present with severe hypotonia and respiratory distress at birth they often require intensive supportive care. Long-term survivors are non-ambulant, ventilator feeding tube–dependent generally show additional organ manifestations, indicating that myotubularin does play vital role tissues other than muscle. For XLMTM several...
Abstract The aim of our study was to evaluate the efficacy adenotonsillectomy for treatment obstructive sleep apnea syndrome (OSA) in pediatric patients with Prader‐Willi (PWS), and describe postoperative complications. Five (4 males; median age, 4.4 years; range, 1.6–14.2 years) were studied. All underwent an overnight cardiorespiratory study. had adenotonsillar hypertrophy (ATH), two also obese. preoperative apnea/hypopnea index (AHI; range) 12.2 (9.0–19.9) events/hr; mean oxygen...
Background: Congenital central hypoventilation syndrome (CCHS) is a rare disorder whose clinical phenotype closely related to genotype. Methods: A retrospective analysis has been conducted on 22 patients with CCHS, who were referred the Pediatric Pulmonology and Respiratory Intermediate Care Unit of Bambino Gesù Children's Hospital (Italy) for multidisciplinary follow-up program between 2000 2020. Results: Apnea cyanosis most frequent symptoms at onset (91%). Overall, 59% required...
Medications with methyl-prednisolone sodium succinate containing lactose, which potentially contains traces of cow's milk proteins (CMP), could cause allergic reactions or compromise treatment acute in sensitized patients. We describe the unusual case a one-year-old child affected by short bowel syndrome and history severe allergy (CMA) anaphylactic reaction due to intravenous administration (Solu-Medrol 40 mg, Pfizer). He was admitted our hospital for respiratory failure initially treated...
Aim To identify subgroups regarding paediatricians' awareness, attitude, practice and satisfaction about management of Sleep-Disordered Breathing (SDB) in Italy using Latent Class Analysis (LCA). Methods A cross-sectional study was conducted on a large sample Italian paediatricians. Using self-administered questionnaire, the collected information 420 Paediatric Hospital Paediatricians (PHPs) 594 Family Care (FCPs). LCA used to discover underlying response patterns, thus allowing...
E-cigarettes are devices which allow to aerosolize liquids containing nicotine or other substances. Ever since they were released on the market in 2006, number of users have been constantly increasing, especially among adolescents, ranging from 7,6% 9,3% age group 18-24 years old 2014 2019. Hand hand with spread many efforts understand their impact health. EVALI (E-cigarette Vaping product use Associated Lung Injury) is an emerging condition a heterogeneous presentation several reported...
Pediatric palliative care (PPC) is an active and total approach to the of children with life-limiting conditions their families. PPC programs provide ongoing treatment for medical complexity (CMC), many whom will reach adulthood. Aim study was describe a population CMC attendingin six preselected months Respiratory Intermediate Care Unit tertiary referral hospital southern central Italy. We enrolled all patients admitted our unit in registered pathologies different categories childhood...
During recent years, interest on Sleep Disordered Breathing (SDB) in pediatric age has increased, due to the impact quality of life, psycho-physical attitude and other serious morbidities if undiagnosed untreated. Italian Pediatric Respiratory Diseases Society (SIMRI) SDB-Working Group carried out an exploratory survey Italy, from January December 2016, assess diagnostic therapeutic pathways, perception relevance SDB Hospitals. A questionnaire was sent 180 Units (PUs) distributed throughout...
Feathers are not commonly considered as foreign bodies causing soft tissue infections in children. Previous literature reports only eight published cases involving feather-related neck infection infants. In our case, we first describe the association between feather-induced abscess and intrathoracic mass due to mediastinal migration of infection. A 14-month-old female baby arrived at Emergency Department ‘Bianchi Melacrino-Morelli’ Hospital Reggio Calabria with a 15-day history persistent...
Congenital central hypoventilation syndrome (CCHS) is characterized by alveolar increasing during sleep and affected patients are unable to perceive respond hypercarbia with increased ventilation arousal sleep. PHOX2B gene mutations considered as responsible for CCHS. Most of CCHS heterozygous polyalanine expansion (PARMs) in exon 3, but 10% classic non-polyalanine (NPARMs) the gene.
The authors have no conflicts of interest to declare.
Abstract Information gathered with built‐in software (BIS) on new ventilators allow clinicians to access long‐term noninvasive ventilation (LTNIV) data. Nevertheless, few evidence are available in literature that highlight potential strengths and disadvantages of using BIS pediatrics. We aim evaluate the use a cohort 90 children LTNIV our unit, focusing mainly adherence, air leaks, residual sleep events. found caregivers' perception ventilator is independent from objective adherence ( P =...
Breathing disturbances are often a major clinical concern during wakefulness of classic form Rett syndrome, but data for atypical forms lacking. We report the case 20-month-old female affected by congenital variant that is characterized severe hypotonia and neurodevelopment impairment. She presented hypoventilation, persistent periodic breathing sustained desaturation sleep time, without obstructive nor central events; pulse oximetry capnography were strictly normal. To best our knowledge,...