A5079124768- Remote Sensing in Agriculture
- Soil and Land Suitability Analysis
- Autophagy in Disease and Therapy
- Single-cell and spatial transcriptomics
- Biochemical effects in animals
- Cancer, Hypoxia, and Metabolism
- Migraine and Headache Studies
- Neurological Disorders and Treatments
- Parasite Biology and Host Interactions
- Extracellular vesicles in disease
- Remote Sensing and Land Use
- Insect Utilization and Effects
- Aldose Reductase and Taurine
- Cancer Genomics and Diagnostics
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Insect and Arachnid Ecology and Behavior
- Land Use and Ecosystem Services
- Neuroinflammation and Neurodegeneration Mechanisms
- Mitochondrial Function and Pathology
- Ecosystem dynamics and resilience
Yangzhou University
2024
Southeast University
2024
Beijing Hospital of Traditional Chinese Medicine
2024
Capital Medical University
2024
Burning Rock Biotech (China)
2022
Neuroinflammation is acknowledged as a pivotal pathological event after cerebral ischemia. However, there limited knowledge of the molecular and spatial characteristics nonneuronal cells, well interactions between cell types in ischemic brain. Here, we used transcriptomics to study hemisphere mice stroke sequenced transcriptomes 19,777 spots, allowing us both visualize transcriptional landscape within tissue identify gene expression profiles linked specific histologic entities. Cell...
Abstract Background Acute ischemic stroke is a common neurological disease with significant financial burden but lacks effective drugs. Hypoxia-inducible factor (HIF) and prolyl hydroxylases (PHDs) participate in the pathophysiological process of ischemia. However, whether FG4592, first clinically approved PHDs inhibitor, can alleviate brain injury remains unclear. Methods The infarct volumes behaviour tests were analyzed mice after systemic administration FG4592. knockdown HIF-1α...